Results 131 to 140 of about 685,370 (269)

What Drives University Students' Sustained Participation in Volunteering? A Thematic Analysis from the Ecological Systems Theory (EST) Perspective. [PDF]

Behav Sci (Basel)
Luo Z, Peng X.
europepmc   +1 more source

Telerehabilitation in the Finnish Outpatient Rehabilitation Setting from the Perspective of the Socio-Technical Systems Theory. [PDF]

Int J Environ Res Public Health, 2023
Partanen T, Seppänen-Järvelä R, Hiekkala S, Lindh J.   +3 more
europepmc   +1 more source

Iron homeostasis disruption and lipid peroxidation in skeletal muscle during short‐term immobilization

FEBS Open Bio, EarlyView.
14‐day casting‐induced immobilization reduced gastrocnemius muscle mass and increased non‐heme iron and ferritin heavy chain levels. Despite iron accumulation, transferrin receptor 1 and iron regulatory protein 2 were paradoxically upregulated. Lipid peroxidation was elevated without compensatory antioxidant responses.
Haruka Yokogawa, Kazuhiko Higashida, Naoya Nakai   +2 more
wiley   +1 more source

Experiences and Support Needs of Parents of Children with Strabismus: A Family Systems Theory Perspective. [PDF]

J Multidiscip Healthc
Zhao BB, Wang H, Luo N, Zhang ZZ.
europepmc   +1 more source

Proteasomal degradation of intracellularly expressed Amblyomin‐X limits suicide gene therapy potential in melanoma cells

FEBS Open Bio, EarlyView.
This study explores the feasibility of expressing the antitumoral protein Amblyomin‐X through a suicide gene therapy approach and investigates its intracellular fate after gene delivery. Although the gene is efficiently expressed, melanoma cells rapidly degrade the Amblyomin‐X protein via proteasome activity.
Victor Dal Posolo Cinel, Carlos DeOcesano Pereira, Aline Ramos Maia Lobba, Melissa Regina Fessel, Ana Marisa Chudzinski‐Tavassi   +4 more
wiley   +1 more source

Control systems theory revisited: new insights on the brain clocks of time-to-action. [PDF]

Front Neurosci, 2023
Ferber SG, Weller A, Soreq H.
europepmc   +1 more source

Systemic dysregulation of apolipoproteins in amyotrophic lateral sclerosis serum

FEBS Open Bio, EarlyView.
Amyotrophic lateral sclerosis (ALS) is a fatal disease that damages motor neurons. This study found that people with ALS show significant changes in blood fats and the proteins that carry them. Several apolipoproteins were higher, lipid balances were altered, and normal protein–lipid relationships were disrupted.
Finula I. Isik, Russell Pickford, Hannah C. Timmins, Olivier Piguet, Glenda M. Halliday, Matthew C. Kiernan, Woojin Scott Kim   +6 more
wiley   +1 more source

Components of the Support-Education System of Orem's Nursing Systems Theory in educational technologies for HIV prevention among adolescents and young people: a scoping review. [PDF]

BMC Nurs
Maximiano LCS, Brito VCDNG, Andrade FB, de Abrantes RM, Medeiros JA, Andrade RM, Costa ENF, da Cunha Oliveira ACGDP, Feijão AR.   +8 more
europepmc   +1 more source

Applying ecological systems theory to juvenile legal system interventions outcomes research: a measurement framework. [PDF]

Front Psychol, 2023
Sheerin KM, Brodell R, Huey SJ, Kemp KA.
europepmc   +1 more source

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

FEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane, Lea Nikolić, Lorenzo Maraio, Thomas Goiran, Nathan Karpilovsky, Stefano Sellitto, Vangelis Bouris, Jiang‐An Yin, Ronald Melki, Edward A Fon, Adriano Aguzzi, Elena De Cecco   +11 more
wiley   +1 more source