Results 141 to 150 of about 694,403 (269)

PANoptosis in the pathogenesis of myelodysplastic syndromes

Molecular Oncology, EarlyView.
PANoptosis, a combination of three types of programmed cell death, is mediated by a large protein complex called a PANoptosome. In healthy bone marrow hematopoietic cells, PANoptosis is restricted by inhibitory signaling. In MDS, bone marrow cells become sensitive to the PANoptotic stimuli due to the aberrant inactivation of inhibitory signaling or ...
Rohit Thalla, Jyoti Lamichhane, Cameron Lewis, Peter Breslin, Jiwang Zhang   +4 more
wiley   +1 more source

Components of the Support-Education System of Orem's Nursing Systems Theory in educational technologies for HIV prevention among adolescents and young people: a scoping review. [PDF]

BMC Nurs
Maximiano LCS, Brito VCDNG, Andrade FB, de Abrantes RM, Medeiros JA, Andrade RM, Costa ENF, da Cunha Oliveira ACGDP, Feijão AR.   +8 more
europepmc   +1 more source

Applying ecological systems theory to juvenile legal system interventions outcomes research: a measurement framework. [PDF]

Front Psychol, 2023
Sheerin KM, Brodell R, Huey SJ, Kemp KA.
europepmc   +1 more source

Cancer cell‐intrinsic type 1 interferon: production, signaling, and outcomes within sex‐biased, female malignancies

Molecular Oncology, EarlyView.
The cell‐autonomous roles of interferon type 1 vary based on duration and intensity. While acute, robust signaling results in cancer cell cytotoxic effects, sustained, low‐level signaling is associated with tumor‐promoting effects. This review summarizes current research of IFN‐1 in cancer and within the clinical setting, with an emphasis on female ...
Ashlyn Conant, Nora Badiner, Sharon Asariah, Kiera McGivney, Vishwa Shah, Tise Suzuki, Yevgeniya J. Ioffe, Juli J. Unternaehrer   +7 more
wiley   +1 more source

Qualitative exploration of manual dental records in the digital era using sociotechnical systems theory: insight from a teaching dental institution. [PDF]

J Yeungnam Med Sci
Azman SA, Abidin S, Lin GSS, Halil MHM.
europepmc   +1 more source

Judicial Response to Ecological Environment Risk in China-From the Perspective of Social Systems Theory. [PDF]

Int J Environ Res Public Health, 2022
Sang T, Liu P, Zhao L.
europepmc   +1 more source

Somatostatin receptor 4 (SSTR4) is a tumor suppressor in cutaneous and head & neck squamous cell carcinomas

Molecular Oncology, EarlyView.
This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi, Tuan Khang Huynh, Adway Kadam, Zahra Kardan, Yue Yan, Amina Jamal Laham, Sampath Kumar Loganathan   +6 more
wiley   +1 more source

Structural Model of Medication Errors in Clinical Nursing: A Structural Equation Model Based on the Ecological Systems Theory. [PDF]

J Nurs Manag
Kim J, Song Y.
europepmc   +1 more source

Novel gain-tuning for sliding mode control of second-order mechanical systems: theory and experiments. [PDF]

Sci Rep, 2023
Xuan-Mung N, Nguyen NP, Pham DB, Dao NN, Nguyen HT, Ha Le Nhu Ngoc T, Vu MT, Hong SK.   +7 more
europepmc   +1 more source

Establishing an assay to evaluate d‐amino acid oxidase enzyme kinetics and inhibition using WST‐8 redox dye

FEBS Open Bio, EarlyView.
This study investigated a novel WST‐8‐based assay for evaluating d‐Amino acid oxidase (DAO) inhibitors. We confirmed its effectiveness using known inhibitors and found that uremic toxins possess relatively weak inhibitory activity compared to existing drugs.
Kahoko Miyake, Yuki Enoki, Yuka Nakazawa, Kazuaki Taguchi, Kazuaki Matsumoto   +4 more
wiley   +1 more source