Results 111 to 120 of about 92,405 (289)

Optimized Detection of Left Ventricular Hyperpolarized [1‐13C]Pyruvate Signal in Human Cardiac Metabolic Imaging

Magnetic Resonance in Medicine, EarlyView.
ABSTRACT Purpose This study aimed to improve the analysis of the left ventricular (LV) blood pool hyperpolarized [1‐13C]pyruvate signal for a more reliable quantification of downstream metabolic outcome. Methods Hyperpolarized [1‐13C]pyruvate magnetic resonance spectroscopic images were acquired dynamically at 3 Tesla in 106 participants (NCT03685175).
Fatemeh Khashami, Ivan E. Dimitrov, Maximilian Fuetterer, Stefan Glöggler, Bei Zhang, Egzona Tan, Sebastian Kozerke, Anke Henning, Tarique Hussain, Craig R. Malloy, Nisha Unni, Vlad G. Zaha, CTOX Trial Investigator(s), Sheeba Cantanelli, Isaac Chan, Suzanne Cole, Suzanne Conzen, Glenda Delgado, Deborah Farr, Joshua Gruber, Barbara Haley, Dawn Klemow, Jenny Li, Heather McArthur, Alka Mallik, Poorni Manohar, Ina Patel, Namrata Peswani, Sangeetha Reddy, Navid Sadeghi, Samira Syed   +30 more
wiley   +1 more source

Improved Myocardial Sodium Quantification at 7 T Using Interleaved 23Na/1H pTx MRI With Motion and Anatomy‐Based B1 Correction

Magnetic Resonance in Medicine, EarlyView.
ABSTRACT Purpose To improve accuracy and repeatability of myocardial 23Na quantification in cardiac MRI at 7 T by combining retrospective respiratory and cardiac motion correction with a novel anatomy‐based B1 bias field correction. Methods In this study, a dual‐nuclear interleaved 23Na/1H MRI sequence at 7 T was applied.
Laurent Ruck, Nico Egger, Benedikt Zobler, Judith Schirmer, Sophia Nagelstraßer, Andreas Bitz, Tanja Platt, Simon Konstandin, Christoph Kopp, Michael Uder, Armin Michael Nagel   +10 more
wiley   +1 more source

Free-Breathing, 3D Cardiac Magnetic Resonance Elastography for Myocardial Stiffness Mapping. [PDF]

Magn Reson Med
ABSTRACT Purpose Magnetic resonance elastography (MRE) of the heart has predominantly utilized breath‐held acquisitions with limited anatomic coverage. This work investigates the feasibility of 3D, free‐breathing cardiac MRE. Methods A 3D hybrid radial and EPI acquisition is utilized and combined with retrospective binning of k‐space via physiologic ...
Meyer NK, Sui Y, Magnuson J, Rossman PJ, Glaser KJ, Murphy MC, Manduca A, Chang IC, McGee KP, Kantarci K, Kapoor E, Araoz PA, Ehman RL, Trzasko JD, Arani A.   +14 more
europepmc   +2 more sources

Deep‐Learning‐Based Image Reconstruction to Improve End‐Diastolic and Systolic Cardiac T1 Mapping

Magnetic Resonance in Medicine, EarlyView.
ABSTRACT Purpose To develop an image reconstruction method that enables increased spatial resolution cardiac T1 mapping in both the end‐diastolic and systolic phase, that shows high T1 agreement with the clinical standard. The resolution gain is achieved by increasing the acceleration rate of MOLLI single‐shot images to R = 4, while maintaining a ...
Daniel Amsel, Jens Wetzl, Daniel Giese, Christoph Tillmanns, Rolf Gebker, Kelvin Chow, Michaela Schmidt, Andreas Lingg, Jens Kübler, Patrick Krumm, Thomas Küstner   +10 more
wiley   +1 more source

Age‐Dependent Correlation of Pulmonary Function Impairment and Aortic Arch Stiffness in Mice

Pediatric Discovery, EarlyView.
This study examined the relationship between aortic arch stiffness and lung function in aging mice. Multiple linear regression modeling showed moderate to strong correlations between the rise in aortic arch stiffness and changes in lung function as the mice progressively aged.
Ayman Isbatan, Samuel M. Lee, Ali Imran Sarwar, Yuxing Yuan, Sunny Chen, Maricela Castellon, Dan A. Marian, Richard D. Minshall, Jie Tian, Irena Levitan, Jiwang Chen   +10 more
wiley   +1 more source

Myocardial Perfusion Defects in Hypertrophic Cardiomyopathy Mutation Carriers

Journal of the American Heart Association, EarlyView., 2021
Background Impaired myocardial blood flow (MBF) in the absence of epicardial coronary disease is a feature of hypertrophic cardiomyopathy (HCM). Although most evident in hypertrophied or scarred segments, reduced MBF can occur in apparently normal segments.
Rebecca K. Hughes, Claudia Camaioni, João B. Augusto, Kristopher Knott, Ellie Quinn, Gabriella Captur, Andreas Seraphim, George Joy, Petros Syrris, Perry M. Elliott, Saidi Mohiddin, Peter Kellman, Hui Xue, Luis R. Lopes, James C. Moon   +14 more
wiley   +1 more source

Personalized auricular vagus nerve stimulation: beat-to-beat deceleration dominates in systole-gated stimulation during inspiration - a pilot study

Frontiers in Physiology
Neuromodulation comes into focus as a non-pharmacological therapy with the vagus nerve as modulation target. The auricular vagus nerve stimulation (aVNS) has emerged to treat chronic diseases while re-establishing the sympathovagal balance and activating
Johannes Tischer, Jozsef Constantin Szeles, Eugenijus Kaniusas   +2 more
doaj   +1 more source

6‐Shogaol Attenuates Doxorubicin‐Induced Cardiac and Skeletal Muscle Atrophy by Inhibiting E3 Ubiquitin Ligases and Necroptosis

Phytotherapy Research, EarlyView.
Doxorubicin induces cardiac and skeletal muscle atrophy by upregulating E3 ubiquitin ligases, inhibiting myogenic regulatory factors, and activating necroptosis. Cardiac atrophy can further exacerbate cardiotoxicity. 6‐Shogaol negatively regulates these processes and attenuates doxorubicin‐induced cardiac and skeletal muscle atrophy.
Xipeng Sun, Yaxian Wang, Quanjun Yang, Bo Xin, Jinlu Huang, Cheng Guo   +5 more
wiley   +1 more source

Electrical Stimulation of Denervated Muscle: A Narrative Review

Artificial Organs, EarlyView.
This review explores existing strategies for stimulating denervated muscle following lower motor neuron injury, including direct electrical stimulation of the muscle and artificial reinnervation to enable more comfortable and efficient indirect functional muscle stimulation.
Linshan Chu, Jonathan C. Jarvis, Brian J. Andrews, James J. FitzGerald   +3 more
wiley   +1 more source

The relationship between the cannabinoids and cardiac remodelling: A comprehensive review of pivotal mechanisms and emerging evidence

British Journal of Pharmacology, EarlyView.
Cardiac remodelling and fibrosis after myocardial infarction or during chronic diseases, such as arterial and pulmonary hypertension or diabetes mellitus, continue to be the more important prognostic factors in determining survival, and so the search for effective anti‐fibrotic interventions is an important target for research and therapy in cardiology.
Anna Krzyżewska, Marta Baranowska‐Kuczko, Hanna Kozłowska   +2 more
wiley   +1 more source