Results 111 to 120 of about 55,187 (266)

Apical hypercontractility mitigates impaired diastolic filling and lower intraventricular haemodynamic forces in human bed rest

Experimental Physiology, EarlyView.
Abstract Prolonged physical inactivity alters the cardiovascular system, including the heart. Long‐term bed rest is known to decrease left ventricular volume and cause diastolic dysfunction; however, the interplay between these changes and their effect on cardiac contractility have been understudied.
Jérémy Rabineau, Fatimah Al‐Darwish, Edwin Mulder, Bram F. Coolen, Fabian Hoffmann, David Hautemann, Jens Tank, Pierre‐François Migeotte, Gustav J. Strijkers, Rob C. I. Wüst   +9 more
wiley   +1 more source

Breijo Electrocardiographic Pattern

Archivo Médico de Camagüey, 2018
Background: the decrease in cardiac electrical systole (short intervals of PR and QTc in the same electrocardiogram, also known as "Breijo electrocardiographic pattern") is increasingly studied.
Francisco Ramón Breijo-Márquez
doaj  

Long‐term adverse cardiovascular changes induced by cocoa shell extract administration through lactation in fetal undernourished and control rats

Experimental Physiology, EarlyView.
Abstract Cocoa shell extract (CSE; rich in antioxidant compounds) administered to adult hypertensive rats exposed to fetal undernutrition (MUN) reduces blood pressure, improving cardiovascular alterations. We aimed to explore lactation as a reprogramming window, evaluating the long‐term effects of CSE supplementation during this period. MUN and control
Santiago Ruvira, Pilar Rodríguez‐Rodríguez, Metee Iampanichakul, Begoña Quintana‐Villamandos, Dolores Morales, David Ramiro‐Cortijo, Silvia M. Arribas   +6 more
wiley   +1 more source

The acute effects of exercise intensity and inorganic nitrate supplementation on the Buckberg ratio in postmenopausal females

Experimental Physiology, EarlyView.
Abstract Menopause increases coronary heart disease risk, in part through reduced oestrogen‐mediated nitric oxide (NO) bioavailability. The Buckberg ratio, an index of myocardial oxygen supply–demand balance, in which higher values reflect more favourable myocardial perfusion, is lower in postmenopausal females (PMFs) than in age‐matched males.
Cassandra C. Derella, Austin C. Hogwood, Joaquin Ortiz de Zevallos, Nathan R. Weeldreyer, Kaitlin M. Love, Arthur Weltman, Jason D. Allen   +6 more
wiley   +1 more source

Computational analysis to assess hemodynamic forces in descending thoracic aortic aneurysms

The Journal of Physiology, EarlyView.
Abstract figure legend Left: Pre‐processing. First, we perform the segmentation of the Computer Tomography angiorgraphy (angio‐CT) scans of a healthy patient, obtaining the surface of a healthy thoracic aorta with a Type III aortic arch. Then, we build nine ideal configurations with Descending Thoracic Aortic Aneurysm (DTAA), varying the aortic arch ...
Francesca Duca, Daniele Bissacco, Luca Crugnola, Chiara Faitini, Maurizio Domanin, Francesco Migliavacca, Santi Trimarchi, Christian Vergara   +7 more
wiley   +1 more source

Elucidating the cellular determinants of the end‐systolic pressure‐volume relationship of the heart via computational modelling

The Journal of Physiology, EarlyView.
Abstract figure legend Using a multiscale computational model of left ventricular electromechanics, we investigated how sarcomere dynamics influence the end‐systolic pressure‐volume (ESPV) relationship in ejecting beats compared to isovolumetric beats.
Francesco Regazzoni, Corrado Poggesi, Cecilia Ferrantini   +2 more
wiley   +1 more source

Energetic microdomains and the vascular control of neuronal and muscle excitability: Toward a unified model

The Journal of Physiology, EarlyView.
Abstract figure legend The capillary–mitochondria–ion channel (CMIC) axis scales structural resources to match functional workload. (Left) In settings of restricted energetic capacity (e.g. cortical neurons), sparse capillary networks and modest mitochondrial pools set a lower energetic ceiling, sufficient to support phasic, low‐workload excitability. (
L. Fernando Santana, Scott Earley
wiley   +1 more source

Human placental exposure to pollutant nanoparticles: uptake, translocation and functional impact

The Journal of Physiology, EarlyView.
Abstract figure legend Prenatal exposure to pollutant nanoparticles has been increasingly investigated due to concerns about their potential effects on placental function and pregnancy outcomes. Maternal inhalation of pollutant nanoparticles can result in a pro‐inflammatory response; particles can also translocate across the alveolus epithelial barrier
Katherine L. Bethell, Andrew C. Povey, Edward D. Johnstone, Peter T. Ruane   +3 more
wiley   +1 more source

A constitutive modelling framework for applications to in vivo longitudinal data: Evaluation in a 60‐day head‐down bed rest study on arterial function

The Journal of Physiology, EarlyView.
Abstract figure legend We proposed a computational constitutive modelling framework that leverages longitudinal acquisitions of haemodynamic waveforms at multiple arterial locations to achieve a biomechanical characterisation of their (micro)structural remodelling processes.
Alessandro Giudici, Karen Barchetti, Umit Gencer, Hakim Khettab, Elie Mousseaux, Carole Leguy, Tammo Delhaas, Rosa Maria Bruno, Bart Spronck, Pierre Boutouyrie   +9 more
wiley   +1 more source

Long‐term passive heat acclimation enhances maximal oxygen consumption via haematological and cardiac adaptation in endurance runners

The Journal of Physiology, EarlyView.
Abstract Figure Legend Endurance‐trained runners completed a 5‐week hot‐water‐immersion (HWI) intervention (≥40°C, 45 min, five sessions per week) and a training‐matched control period in a cross‐over design. HWI induced a 33 g increase in haemoglobin mass (Hbmass) and a 10 mL expansion in left‐ventricular end‐diastolic volume (LVEDV), resulting in a 2.
Elliott J. Jenkins, Joseph A. Killick, Owain Zerilli, Andrew J. M. Douglas, Liam Corr, Michael G. Hughes, Joshua C. Tremblay, Mike Stembridge   +7 more
wiley   +1 more source