Results 141 to 150 of about 55,187 (266)

The Role of Inflammation and Immunity in Cardiovascular Disease: Molecular Mechanisms and Therapeutic Targets

open access: yesMedComm, Volume 7, Issue 8, August 2026.
Inflammation in cardiovascular disease is a dynamic and context‐dependent network rather than a secondary response to injury. Mitochondrial danger signaling links metabolic stress to immune activation through TLR priming, NLRP3 inflammasome amplification, cGAS–STING signaling, and immunometabolic gating, providing a basis for more precise therapeutic ...
Jiaxiang Rong   +8 more
wiley   +1 more source

Deep‐Learning‐Based Image Reconstruction to Improve End‐Diastolic and Systolic Cardiac T1 Mapping

open access: yesMagnetic Resonance in Medicine, Volume 96, Issue 2, Page 892-907, August 2026.
ABSTRACT Purpose To develop an image reconstruction method that enables increased spatial resolution cardiac T1 mapping in both the end‐diastolic and systolic phase, that shows high T1 agreement with the clinical standard. The resolution gain is achieved by increasing the acceleration rate of MOLLI single‐shot images to R = 4, while maintaining a ...
Daniel Amsel   +10 more
wiley   +1 more source

An 11-Year-Old Athlete With Dynamic Stenosis of Coronary Artery Anomaly With Normal FFR-Dobutamine But Abnormal iFR-Dobutamine. [PDF]

open access: yesJACC Case Rep
Stark AW   +7 more
europepmc   +1 more source

Dynamic Mode Decomposition (DMD) for Low‐Latency Real‐Time Cardiac MRI

open access: yesMagnetic Resonance in Medicine, Volume 96, Issue 2, Page 623-634, August 2026.
ABSTRACT Purpose To demonstrate dynamic mode decomposition (DMD) for high spatiotemporal low‐latency online reconstruction in 2D real‐time cardiac MRI. Methods DMD was applied to 2D spiral balanced steady state free precession (bSSFP) real‐time adult and fetal cardiac MRI at 0.55 T, with data from 10 healthy adult volunteers (3F/7M; age: 21–49; BMI: 20–
Ecrin Yagiz   +5 more
wiley   +1 more source

Phase-targeting rapid cryofixation of the beating heart and histological analysis unveil contractile state-dependent sarcomere dynamics. [PDF]

open access: yesSci Rep
Tamura S   +8 more
europepmc   +1 more source

A novel selective stabilizer of the ryanodine receptor 2 prevents stress‐induced ventricular arrhythmias without impairing cardiac function

open access: yesBritish Journal of Pharmacology, Volume 183, Issue 15, Page 4321-4343, August 2026.
Abstract Background and Purpose Aberrant activation of type 2 ryanodine receptors (RyR2) causes lethal arrhythmias, such as catecholaminergic polymorphic ventricular tachycardia (CPVT). Developing drugs that suppress RyR2 hyperactivation may be key to novel arrhythmia treatments.
Nagomi Kurebayashi   +29 more
wiley   +1 more source

Evidence for Cardiac Phase-Linked Perception of Heartbeats. [PDF]

open access: yesPsychophysiology
Palmer R   +7 more
europepmc   +1 more source

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