Results 211 to 220 of about 92,405 (289)

P2X7R deficiency alleviates cardiac senescence by enhancing mitophagy via the HuR/TRIM26/NR4A1 axis

open access: yesClinical and Translational Medicine, Volume 16, Issue 3, March 2026.
P2X7R regulates the nucleoplasmic translocation of HuR, thereby enhancing the stability of the E3 ubiquitin ligase TRIM26. TRIM26 directly binds to NR4A1 and promotes its ubiquitination, thereby suppressing mitophagy and increasing reactive oxygen species (ROS) production.
Yixin Zhou   +14 more
wiley   +1 more source

Lachnospiraceae‐Derived Extracellular Vesicles Mediate the Cardioprotective Effects of Barley Leaf in Myocardial Infarction by Improving Intestinal Stem Cell Function

open access: yesJournal of Extracellular Vesicles, Volume 15, Issue 3, March 2026.
ABSTRACT Ischaemic cardiovascular diseases, particularly myocardial infarction (MI), remain the leading causes of morbidity and mortality worldwide. Targeting extracellular vesicles (EVs) from the gut microbiota by diet may provide opportunities to improve cardiovascular health. Barley leaf (BL) has a long history of use in Traditional Chinese medicine
Wenjing Chen   +10 more
wiley   +1 more source

Quantitative MRI Values for Atrial and Ventricular Parameters in Altitude‐Dwelling Youth

open access: yesJournal of Magnetic Resonance Imaging, Volume 63, Issue 3, Page 828-845, March 2026.
ABSTRACT Background The hypoxic environment on the Qinghai Plateau significantly exacerbates myocardial remodeling, with sex/ethnicity‐specific variations in cardiac parameters among local youth. Current cardiac MRI reference values lack data from physiologically adapted populations on this plateau.
Xiumei Xiao, Hui Xu
wiley   +1 more source

Pharmacological increases in circulating ketones fail to alleviate the hypertrophic cardiomyopathy present in the Tafazzin knockdown mouse model of Barth syndrome. [PDF]

open access: yesJ Pharm Pharm Sci
Shafaati T   +14 more
europepmc   +1 more source

Alcohol Septal Ablation in Hypertrophic Obstructive Cardiomyopathy: Long‐Term Follow‐Up of Deformations and Hemodynamics

open access: yesJournal of Magnetic Resonance Imaging, Volume 63, Issue 3, Page 859-871, March 2026.
ABSTRACT Background A detailed evaluation of hemodynamics, supportive morphology, and deformation may help uncover the pathophysiology of hypertrophic obstructive cardiomyopathy (HOCM) and the changes wrought by alcohol septal ablation (ASA). Purpose To investigate the global cardiac volume, myocardial deformation, and hemodynamic characteristics ...
Kenichiro Suwa   +5 more
wiley   +1 more source

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