Results 221 to 230 of about 54,609 (316)

HUWE1 in Skeletal Muscle Prevents Muscle Fatigue via Maintaining Iron and Calcium Homeostasis

open access: yesAdvanced Science, Volume 13, Issue 4, 19 January 2026.
This study investigates the impact of iron homeostasis on exercise. Loss of the HECT domain‐containing ubiquitin ligase E3 (HUWE1) in skeletal muscle restrains the exercise performance in mice with downregulated ferroportin expression leading to iron overload, which is ameliorated by dietary iron restriction.
Huike Jiao   +10 more
wiley   +1 more source

A Rare but Severe Long‐Term Complication of an Implantable Chamber

open access: yesClinical Case Reports, Volume 14, Issue 1, January 2026.
ABSTRACT Long‐term implantable ports may cause severe complications even years after placement. This case highlights the importance of verifying catheter integrity and tip position before reusing a dormant central venous access device, as delayed mechanical erosion can lead to pericardial effusion and life‐threatening cardiac tamponade.
Raphael Grolleau   +5 more
wiley   +1 more source

Optimizing IABP-patient interaction in VA-ECMO via transcranial doppler. [PDF]

open access: yesUltrasound J
Yepes-Velasco AF   +2 more
europepmc   +1 more source

Apical Sparing of Longitudinal Strain and Myocardial Fibrosis in Hypertensive Patients and Spontaneously Hypertensive Rats: Based on Speckle Tracking and Histological Analysis

open access: yesClinical Cardiology, Volume 49, Issue 1, January 2026.
Hypertensive cardiac hypertrophy shows a “basal‐damage, apical‐sparing” pattern in strain and fibrosis. This apical sparing correlates with diastolic dysfunction and hypertrophy progression, highlighting its value as an observable clinical hallmark of adverse remodeling. ABSTRACT Background This study aimed to investigate regional myocardial strain and
Chunyan Huang   +6 more
wiley   +1 more source

Integrative Evidence From Metabolome‐Wide Mendelian Randomization and Animal Models Implicates Tyrosine in Cardiac Hypercontractility and Arrhythmia Risk

open access: yesFood Frontiers, Volume 7, Issue 1, January 2026.
Plasma metabolome‐wide Mendelian randomization analysis established a causal link between tyrosine and arrhythmia. GWAS meta‐analysis identified tyrosine‐associated loci linked to cardiovascular risk factors. Animal studies confirmed that oral tyrosine intake modulates heart rhythm via adrenergic signaling activation.
Zhikang Cao   +7 more
wiley   +1 more source

Kaempferitrin Attenuates Lipopolysaccharide‐Induced Cardiac Dysfunction Through Suppression of the NF‐κB/NLRP3 Signaling Pathway

open access: yesImmunity, Inflammation and Disease, Volume 14, Issue 1, January 2026.
ABSTRACT Purpose The inflammatory activation and metabolic disorders of cardiomyocytes are essential mechanisms in sepsis‐related cardiac dysfunction. Kaempferitrin (Kae), a flavonoid compound, possesses various properties including anti‐inflammatory and anti‐glycation effects. Hence, the current study is conducted to investigate the protective effects
Hongyu Kuang   +3 more
wiley   +1 more source

Biomechanical and Functional Response of 3D Printed Materials and Silicone Elastomers Compared to Human Aortic Tissues

open access: yesJournal of Biomedical Materials Research Part A, Volume 114, Issue 1, January 2026.
ABSTRACT Synthetic materials that mimic the biomechanical and functional response of vascular tissues have applications in medical device testing and surgical training. 3D printing has emerged as a key technology to build complex patient‐specific anatomical models with multiple materials to mimic a range of tissue types.
Vivian Tan   +4 more
wiley   +1 more source

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