Results 81 to 90 of about 5,393,834 (251)

Soft, Multi‐Wavelength Photoplethysmography Enables Reliable Neonatal Blood Pressure Monitoring Via Error Stratification

Advanced Science, EarlyView.
A soft hybrid multi‐wavelength PPG wearable acquires neonatal signals. Synchronized PPG and invasive ABP data are segmented into fixed windows. A 1D‐EfficientNet model predicts segment‐level SBP and DBP. Model performance is examined with retrospective subgroup analysis across acquisition conditions.
Wenqi Shi, Lanlan Mi, Jiarong Chen, Biao Liu, Min Wang, Zisheng Dai, Bin Liu, Ruize Gao, Yunfeng Lin, Weiwei Guo, Guoxing Wang, Wenyi Luo, Cheng Chen   +12 more
wiley   +1 more source

Impact of renal denervation on 24-hour blood pressure pattern in patients with resistant hypertension

Фундаментальная и клиническая медицина, 2019
Aim. To estimate the dynamics of 24-hour blood pressure pattern in patients with resistant hypertension after renal denervation in comparison with the conservative treatment group.Methods. We enrolled 45 patients (21 men and 24 women, mean age 53 (43-66)
T. Yu. Chichkova, S. E. Mamchur, M. P. Romanova, E. A. Khomenko   +3 more
doaj   +1 more source

A Novel Pak1 Activator Ameliorates ER Stress for HFpEF Therapy

Advanced Science, EarlyView.
Chronic metabolic stress is a major contributor to HFpEF progression. Under prolonged metabolic stress, Pak1 activity becomes impaired, contributing to disrupted ER proteostasis, cardiomyocyte apoptosis, fibrosis, and diastolic dysfunction. Mechanistically, Pak1 overexpression activates the ERK1/2–MNK1–eIF4E signaling axis, promotes translational ...
Honglin Xu, Hongyuan Zhang, Tayyiba Azam, Susanne S. Hille, Yingjuan Liu, Min Zi, Jiaqing Lang, He Yu, Yujia Cao, Bernard D. Keavney, Tamer M. A. Mohamed, Jessica M. Miller, Riham R. E. Abouleisa, Ming Xu, Elizabeth J. Cartwright, Oliver J. Müller, Ming Lei, Xin Wang   +17 more
wiley   +1 more source

Causal Effects Between Blood Pressure Variability and Alzheimer's Disease: A Two‐Sample Mendelian Randomization Study

The Journal of Clinical Hypertension
Alzheimer's disease (AD), an escalating global public health concern, demonstrates complex pathogenesis involving both genetic predisposition and vascular components. Blood pressure variability (BPV) has been implicated in neurodegenerative diseases, but
Pingping Jia, Ziyu Hao, Karen Yiu, Kelvin Tsoi   +3 more
doaj   +1 more source

Printable Piezoresistive Hybrid Hydrogels Based on 2D MoS2 for Flexible Pulse Sensing

Advanced Science, EarlyView.
Hybrid 1T‐MoS2‐based hydrogels are engineered through UV curing and 3D printing to achieve tunable electromechanical properties for wearable sensing. These soft architectures enhance mechanical stability and reproducible piezoresistive responses within the physiological pressure range.
Jenny Flores, Arianna Bertero, Luca Ceseracciu, Daniel Jiménez‐Boland, Sara Domenici, Mattia Bramini, Paola Sánchez‐Moreno, Erica Scarcelli, Domenico Galdiero, Pavel Fedorov, Daniil Karnaushenko, Rossella Sesia, Ignazio Roppolo, Micaela Pozzati, Mattia Spedicati, Nicolò Petrini, Marco Sangermano, Bartolomeo Coppola, Teresa Gatti   +18 more
wiley   +1 more source

European Society of Hypertension practice guidelines for ambulatory blood pressure monitoring.

, 2014
Given the increasing use of ambulatory blood pressure monitoring (ABPM) in both clinical practice and hypertension research, a group of scientists, participating in the European Society of Hypertension Working Group on blood pressure monitoring and ...
Clement, D., Fagard, R., Zanchetti, A., Parati, G., Myers, M., Waeber, B., vanMontfrans, G., Ohkubo, T., Ruilope, L.M., Imai, Y., Wang, J., Graves, J., Zhang, Y., Omboni, S., Stergiou, G., Bilo, G., Dolan, E., de Leeuw, P., Ogedegbe, G., Palatini, P., Redon, J., Staessen, J.A., Kario, K., Mancia, G., de la Sierra, A., Verdecchia, P., Mengden, T., Mallion, J.M., Head, G.A., Shennan, A., Asmar, R., Lurbe, E., Beilin, L., O'Brien, E., Cardiovascular, Variability   +34 more
core   +1 more source

Increased Disarray of Extracellular Matrix Collagen‐I Fiber Network and Compromised Biomechanics in Aortae From Marfan‐Syndrome Mice Assessed Through Combined Opto‐Biomechatronics

Advanced Science, EarlyView.
Combined structure‐function assessment in aortic rings from Marfan mice using MechaMorph Opto‐Biomechatronics technology relates increased elasticity (stiffness) and dynamic viscosity and less ordered extracellular matrix 3D‐structure (collagen) as potential causes for impaired Windkessel function and compromised haemodynamics in Marfan's syndrome ...
Dominik Schneidereit, Anika Nagel, Vanessa I. T. Zwaans, Laureen Schurr, Jonas Ahr, Michael Haug, Anna Piluso, Alexandra Sporkova, Matthias Karck, Andreas H. Wagner, Oliver Friedrich   +10 more
wiley   +1 more source

Gut Microbiota‐Derived Indole‐3‐Propionic Acid Alleviates Diabetic Osteoporosis Through Nrf2‐Mediated Ferroptosis Suppression

Advanced Science, EarlyView.
Diabetes‐associated dysbiosis is accompanied by reduced Clostridium abundance, impaired microbial tryptophan metabolism, and lower circulating indole‐3‐propionic acid (IPA). Exogenous IPA improves trabecular microarchitecture and bone formation and restores Nrf2‐associated antioxidant signaling in bone marrow mesenchymal stem cells, limiting iron ...
Jinwu Bai, Qinyong You, Gao Si, Daole Hu, Ao Sun, Shilong Su, Ruideng Wang, Jixing Fan, Shan Gao, Tengjiao Zhu, Chun‐Li Song, Fang Zhou, Yang Lv   +12 more
wiley   +1 more source

BRACHIAL-TO-RADIAL-SYSTOLIC-BLOOD-PRESSURE-AMPLIFICATION AND THE IMPACT ON NON-INVASIVELY DERIVED CENTRAL SYSTOLIC BLOOD PRESSURE

, 2014
BRACHIAL-TO-RADIAL-SYSTOLIC-BLOOD-PRESSURE-AMPLIFICATION AND THE IMPACT ON NON-INVASIVELY DERIVED CENTRAL SYSTOLIC BLOOD ...
DS Picone (15795698), RED Climie (14535080), KDK Ahuja (15795704), Michelle Keske (13078767), JE Sharman (14474352)   +4 more
core  

Proteogenomic Profiling of Idiopathic Pulmonary Arterial Hypertension Identifies Sex‐Differential Proteins and Candidate Therapeutic Targets

Advanced Science, EarlyView.
An integrated proteogenomic analysis of 44,137 predominantly European‐ancestry UK Biobank participants aged 40–69 years identifies 12 robust proteins associated with idiopathic pulmonary arterial hypertension. These proteins define a high‐mortality molecular endotype, support early detection and mortality prediction, reveal sex‐differential proteomic ...
Xinjie Lin, Yangchang Zhang, Yang Pu, Duanke Liu, Tao Lei, Kai Ma, Qiyu He, Zheng Dou, Yuze Liu, Dengyuan Liu, Yinge He, Yanshang Wang, Xiaojiao Zheng, Yanbing Ma, Jianrong Zhou, Weiding Zhai, Binbin Su, Li Chen, Shoujun Li   +18 more
wiley   +1 more source