Results 91 to 100 of about 5,393,834 (251)
ROS‐Responsive Nanoparticle Delivery of Dexmedetomidine Protects the Gut Vascular Barrier After Intestinal Ischemia/Reperfusion via the HDAC‐H3K27ac‐TCF4 Axis
Advanced Science, EarlyView.A low dose of dexmedetomidine, delivered by ROS‐responsive nanoparticles, preferentially accumulates in the ischemic intestine and restores gut vascular barrier integrity after ischemia/reperfusion injury. This nanoparticle‐based strategy prevents bacterial translocation and liver damage without cardiorespiratory side effects, working through HDAC ...Hu‐Fei Zhang, Jian‐Tong Shen, Hua‐Hua Zhang, Si‐Qi Gao, Ji‐Ao Wang, Yue‐Ling Wang, Mei‐Ling Li, Zi‐Meng Liu, Yi‐Nan Zhang, Yan Li, Xu‐Yu Zhang +10 morewiley +1 more sourceTowards a Compositional Framework for Describing Human Phenotypes
Advanced Science, EarlyView.The Phenotype Assembly Method (PhenoAM) decomposes phenotype variables into measurable Features and typed Qualifiers, enabling standardized, machine‐readable Phenome Data Elements (PhenoDEs) that preserve measurement context. Applied in the International Human Phenome Project (IHPP), the framework yields 58 371 PhenoDEs and supports component‐level ...Wanting Hu, Yunchao Ling, Xinyue Hu, Wei Chen, Rong Zhou, Xinhao Zhuang, Yanfeng Jiang, Jialu Zhao, Xingdong Chen, Jingchun Luo, Li Jin, Guoqing Zhang +11 morewiley +1 more sourceOrthostatic Systolic Blood Pressure Elevation and Incident Atrial Fibrillation: Insights From the SPRINT Trial
The Journal of Clinical HypertensionExaggerated orthostatic changes in systolic blood pressure (SBP) were associated with adverse cardiovascular events. We aim to assess the association between orthostatic SBP changes and incident atrial fibrillation (AF).Jue Wang, Wenhe Lv, Zhen Wang, Sitong Li, Zhixian Wang, Le Zhou, Yufeng Wang, Lan Ren, Chao Jiang, Liu He, Shijun Xia, Xiangyi Kong, Song Zuo, Yu Kong, Xueyuan Guo, Xiaoxia Liu, Songnan Li, Ribo Tang, Deyong Long, Caihua Sang, Ning Zhou, Xin Du, Jianzeng Dong, Changsheng Ma +23 moredoaj +1 more sourceGenetic variants in novel pathways influence blood pressure and cardiovascular disease risk [PDF]
, 2011 Blood pressure is a heritable trait1 influenced by several biological pathways and responsive to environmental stimuli. Over one billion people worldwide have hypertension ($140mmHg systolic blood pressure or$90mmHg diastolic blood pressure)2. Even small Harst, P. (Pim) van der, Lawrence, Robert W, Sinning, Christoph, Wichmann HE, Preuss, M., Ridker, P.M., Wilensky R, Launer, L, Assimes, Themistocles L., Go, Alan, Heid, I. M., Ingelsson, E., Elosua, R., Fava, C. (Cristiano), Staessen, J.A. (Jan), Kim, HL, Boerwinkle, E., Dong, Y., Prabhakaran, D, van der Schouw, Y.T., Hicks, Andrew A, Ongen, H. (Halit), Palmer, L.J., Langefeld, C.D. (Carl), Hengstenberg, Christian, Wichmann, H. Erich, Kangas, Antti J., Glazer, NL, Shin Cho, Y. (Yoon), Smith, Nicholas, Peters, Annette, Tayo, B. (Bamidele), Young, J. Hunter, Smith, AV, Day, I.N.M., Lathrop, Mark, Steinle, NI, Stančáková, A, Curhan, G. C., Dong, YB, Preuss M, Cooper, Richard S, Glazer, N., Kuznetsova, T, Barroso, Inês, Ong, R.T., Lawrence, Robert W., O´Connell, J.R., Forrester, T, Corsi, A.M. (Anna Maria), Vinay, D G, Chambers, John C, Tomaszewski, M, Palmer, Lyle J., O'Donnell, CJ, Frayling, Timothy M., Nilsson, Peter M., Wichmann, H.E. (Heinz Erich), Floege, J., Seielstad, M, Hwang, S. J., Roberts, Robert, Igl, W., Harris, T.B. (Tamara), Knowles, J., Ongen, Halit, Voelker, Uwe, Quertermous, T., Seielstad, Mark, Heckbert, Susan R., Lee, NR, Miki, T., Johnson, A.D. (Andrew), Li, Mingyao, Nilsson, P. (Peter), Munroe, PB, Kong, A., Ong, RT, Schillert, A., Perret, Claire, Ludwig, Barbara, Thorgeirsson, G., Milaneschi, Y. (Yuri), Smith, GD, Rivadeneira, F, Turner, S. T., Chang, Yen-Pei C, Bilo, H. J., Sidney, Steven, Fava, Cristiano,, Salako, T., Iwai, N., Lackner, K., Strachan, David P., Schreiber, S., Morris, R.W. (Richard), Ohkubo, T, Johnson, T, Ong, RTH, Nelson C, Sinning C, Bolton, J.A.H., Chen L, Wu, Fenny, Rudan, I. (Igor), König, I. R., Winkelmann, B.R., Orru, Marco, Järvelin, M.-R., Najjar, S., Nicaud, Viviane, O’Donnell, Christopher J., Tripathy, Vikal, Uitterlinden, Andre G, Braund, Peter S., van Gilst, WH, Smith, A.V. (Albert Vernon), Quertermous T, Völker, U. (Uwe), Fortmann, Stephen, Knouff, C.W., Zillikens, M. C., Sternberg, M. J., Rice, K.M., Zhang, W., Illig T, Levy, D. (Daniel), Taylor, K.D., Gyllensten, Ulf B, Andersen, K., Mani, K Radha, Milaneschi, Y, Raitakari, Olli T., Vitart, Veronique, Völzke, H. (Henry), Emilsson, V., Hercberg, S., Iribarren, Carlos, Nguyen, Khanh-Dung Hoang, Waterworth, Dawn M., Lucas, Gavin, Cupples, L.A., Kähönen, M., Loley, Christina, Cavalieri, M., Dominiczak, Anna F, Wright, A.F., van der Schouw, YT, Gao, X., Hadley, D., Sijbrands, Eric J.G., Burtt N, Talmud, P.J., Hakonarson, H.H., et al, Kangas, AJ, Gale, D. P., Graessler, J, Wareham, N.J., Scharnagl H, Li, Y., de Faire, Ulf, Longstreth Jr., W.T., Wild, S.H. (Sarah), Heath, S., Weder, A.B. (Alan), Erdmann, Jeanette, Gabriel SB, Zhu, H. (Haidong), Artigas, M.S., Dehghan A, Stancáková, A. (Alena), Illig, T., Soininen, P. (Pasi), Galan, P., Li, YL, Yang, Q., van Gilst, Wiek H, Zhang, WH, Swift, A.J. (Amy), Vineis, P., Hicks, Andrew A., Brand, Stefan Martin, Tai, E Shyong, Jackson, A.U., Knouff, Christopher W., Hoffmann M, Wilson, James F, Whincup, P.H., Wong, TY (Tien Yin), Longstreth Jr, W. T., Org, E, Bornstein, SR, KidneyGen Consortium, Völzke, H, Parker, AN, Wagenknecht, Lynne E., Wass, M. N., Schillert A, Witteman, Jacqueline C.M., Kroemer, H. K., Wu, Y, Hofman A, Guarrera, S, Köttgen, Anna, Chen, I.Y., Dobnig H, Erdmann, J, Adeyemo, A. (Adebowale), Nelson, C., Wright, AF, Boban, M., Larson, Martin G., Najjar, Samer S., Meschia, James F, Farrall, M. (Martin), Hercberg, Serge, Palmer, LJ, Kooner, J.S. (Jaspal), Parker, A. N., Beckmann, Jacques S, Hicks, A.A., Sijbrands, EJ, ICBP Consortium (Meitinger, T. ; Wichmann, H.-E. ; Gieger, C.), Hua Zhao, Jing, Brand, Eva, Waterworth, D., Melander, O, Qu, Liming, Polasek, Ozren, Miki, T, Grässler, J., Medack A, Shriner, D, Chang, Yen-Pei C., Snieder, H. (Harold), Uiterwaal, C.S.P.M., Salomaa, V. (Veikko), van Duijn, Cornelia M., Sehmi, J.S., Zerres, K., Mosley, Thomas H., Kao, WHL, Psaty, B. M., Groop, L. (Leif), Lakatta, Edward G., Ehret, Georg B, Heckbert, S. R., Renner W, Sõber, S. (Siim), Terzic, J. (Janos), Bakker, S.J.L. (Stephan), Jackson, Anne U, Newton-Cheh, C, Ikram, Arfan, Snieder, Harold, Grobbee, D.E. (Diederick), Marciante, Kristin, Struchalin, M., Gabriel, Stacey B., Fowkes, F. Gerald R., Palmas, W, Collins, FS, Lumley, Thomas, Fowkes, F.G.R., Kim, Hyung Lae, Janipalli, C.S., Hernandez, Dena, Zhao, JH, Kumar, M. V. Kranthi, Kuusisto, J. (Johanna), Laakso, M. (Markku), Shrine, N.R., Kivimaki, M., Chen, M.H., Longstreth, W. T., Jr., Chang, Y.-P.C. (Yen-Pei), Langefeld, Carl D., Pramstaller, PP, Hoang Nguyen, KD, Uiterwaal, CSPM, Greiser, K. H., Vollenweider, P, Smith, A., Najjar, S.S. (Samer), Rotimi, C, Halperin, Eran, Coresh, J., Ala-Korpela, M. (Mika), Barroso, I.E. (Inês), Zhu, Haidong, Elliott, P., Fuchsberger, C., Prabhakaran, Dorairaj, Palmas, W., Hilton, Gina, Demissie, Serkalem, Whincup, Peter H., Tanaka, T, Humphries, S.E. (Steve), Cupples LA, Steinle, Nanette I., Hwang, S-J, Psaty, Bruce M., Salako, Tunde, Onland-Moret, N.C. (Charlotte), Jarinova, O., Mägi, R., Vinay, D. G., Beilby, John P, Smith, N.L., Elosua, Roberto, Demirkan, A, Tuomilehto, J., Zhai, G. (Guangju), Swift, Amy J, Galan, P, Köttgen, A., Morrison, Alanna C, Hoffmann, Michael M., Arfan Ikram, M., Uiterwaal, CS, Walker, M.C., Gaunt, Tom R., Deloukas, P, Launer, L. J., Ehret, G.B., Prabhakaran, D., Lakatta, EG, Krämer, B. K., Holm H, Bis, J.C. (Joshua), Franke, A., Cooper, Jackie A., Chasman, D.I. (Daniel), Lieb, W., Mohlke, K.L., Campbell, Harry, Teumer, A. (Alexander), Garcia, Melissa E, Voight, Benjamin F, Lyytikäinen, L.-P., Pichard AD, Scott, J., Ellinghaus, D., Mattace-Raso, Francesco U.S., McKenzie, C.A., Lyytikainen, L-P, Bochud, M., Hlatky M, Bergmann, S, Plump, A., Tang, Hua, Lawrence, RW, Medack, A., Parsa, A., Khaw, KT, Hartikainen, AL, Schnabel R, Talmud, Philippa J., Hoffman Bolton, Judith A., Grosshennig A, Heckbert, Susan, Yajnik, C.S., Charchar, Fadi J., Heckbert, S.R. (Susan), Satler, Lowell, Rotter JI, Hernandez, D.G. (Dena), Erdmann, J. (Jeanette), Chasman, DI, Adeyemo, A, Zhu, H, Smith, G.D., Denniff, M. (Matthew), Absher D, Matthai, W., Doering, Angela, Young, J Hunter, Rao, Dabeeru C., Thompson, J.R., Zelenika, D, Mattace-Raso, Francesco U S, Alexander, Myriam, Zhu, X, Lathrop, G.M. (Mark), Li, M., Langefeld, C.D., Bots, ML (Michiel), Kangas, A.J. (Antti), Bis, J.C., Wilson, J.F., Doumatey, Ayo P., Samani, N.J., Meisinger C, Okamura, Tomonori, Kent, K.M., Kathiresan, S, Rader, Daniel J., Schwartz, S.M. (Stephen), Raitakari, O., Friedrich, N., International Consortium for Blood Pressure Genome-Wide Association Studies, Platou, C. (Carl), Connell, J. M., Samani NJ, Beilby, JP, Palmer, ND, Wong, Tien Y, Knowles, Joshua, Howard, P, Soranzo, N., Adair, LS, Schmidt, H., Epstein, S., Waeber, G., Pouta, A., Rotter, J. I., Perola, M. (Markus), Wichmann, HE, Day, Ian N.M., Preuss, Michael, Brand, E (Eddy), Isaacs, A., Kardia, Sharon L. R., Homan van der Heide, J. J., Chang, Y-PC, Arnett, D. K., Hwang, S.J., Brand, E, Burton, P.R. (Paul), Wilson, James F; id_orcid, Corsi, Anna Maria, O'Reilly, P.F., Bergmann, S., Voelker, U, Völker, U., Rettig, R. (Rainer), Kuh, D, Bickel, Christoph, Frayling, Timothy M, Farrall, M., Teumer, Alexander, Umemura, S., Matullo, G., Dominiczak, Anna F., Demirkan, A. (Ayşe), Wells, G.A., Ehret, Georg B., Laan, M, Emilsson, Valur, Zelenika, D. (Diana), Aulchenko, Yurii S., Cupples, L. Adrienne, Bakker, Stephan J.L., Peden, John F., O’Reilly, Paul F., Lakatta, Edward G, Vasan, RS, Beckmann, J.S. (Jacques), Lawlor, D. A., Loehr, Laura R., Prokopenko, I, Kuznetsova, T. (Tatiana), Chambers, J.C., Khaw, Kay-Tee, Viigimaa, M., Day, I.N., Raffel, Leslie J, Sijbrands, E.J.G. (Eric), Taylor, A., Schlieper, G., van der Schouw, Yvonne T., Ganesh, Santhi K, Samani, Nilesh J, Peltonen, L. (Leena Johanna), Kardia, S.L., Tomaschitz A, Rodeheffer, R. J., McArdle, W.L., Melander, O., Parsa, A. (Afshin), Cooper, J.A., Wong, T.Y., Zitting, P. (Paavo), Sidney, S., Fox, E.R. (Ervin), Gretarsdottir, Solveig, Khanh-Dung Hoang, Nguyen, Hayward, Caroline, Hofman, A. (Albert), Nahrstedt, J., Erdmann J, Ohkubo, T., Voight, B.F., Igl, Wilmar, Steinle, N.I. (Nanette), Wild, S. H., Lackner, K. J., CARDIoGRAM Consortium, Kroemer, H.K., Ala-Korpela, Mika, Caulfield, MJ, Haritunians, T., Coresh, J, Fowkes, FGR, Rasheed, A. (Asif), Balmforth AJ, Schmidt, R., Winkler K, Kooner, JS, McKenzie, Colin A., Hicks, AA, Kuusisto, Johanna, Aspelund, T, Chang, Y.-P.C., Mattace-Raso, FU, Adeyemo, A., Morris, Richard W, Lakatta, E.G., International Consortium for Blood Pressure Genome-Wide Association Studies,, Dreisbach, A.W., Oostra, B.A., Emilsson, V, Watkins, Hugh, Freyer, J., Shi, G. (Gang), Kulkarni, SR, Thelle, Dag S, Morken, Mario A, Fowkes, F.G.R. (Gerald), Jafar, T.H., Ramachandran, Vasan, O'Reilly, P.F. (Paul), Renner, Wilfried, Viigimaa, Margus, Saleheen, Danish, Spector, T.D., Sijbrands, E.J., Loos, R.J.F., Kinra, S, Howard, P., Sjögren, Marketa,, Scott, LJ, Gulde, Stephanie, Kathiresan, Sekar, Rice, Kenneth M, Larson, Martin G, Wilson, JF, Gyllensten, U.B., Han, B.-G., Kardia, S.L. (Sharon), Holm, H., Abecasis, G. R., Lohman, Kurt K., Aulchenko, Yurii, Rupprecht HJ, Arora, P., Bots, Michiel L., Münzel T, Absher, D., Alexander, M. (Myriam), Hwang, Shih Jen, Kulkarni, S.R., Aulchenko, Yuriy, Gaunt, Tom R, Wilson, J.F. (James), Wong, TY, Sõber, Siim, Meitinger, T. (Thomas), Wain, Louise V, Bickel C, Grosshennig, A., Cooper, M.N. (Matthew), Zukowska-Szczechowska, E., Hopewell, J.C., Barbalic M, McPherson, R., Ikram, M.A. (Arfan), Palmen, J., Barroso, Ine S., Lee, JY, Wagenknecht, L.E. (Lynne), Lackner, Karl, Hlatky, M., Vartiainen, E., Uda, M., Danesh, J, Weder, Alan B., Rivadeneira Ramirez, F. (Fernando), Connell, J.M., Linsel-Nitschke, P., Wong, Tien Y., Böhm BO, Harris, Tamara B, Watzinger, N., Morrison, A.C. (Alanna), Kathiresan, S., Okamura, T. (Tomonori), Ong, Rick Twee Hee, Kettunen, Johannes, Bickel, C., Campbell, H. (Harry), Caulfield, M. (Mark), Groop, L, Boehnke, M, Walker M, Wichmann, H.-E., Kathiresan S, Folsom, A., Willenborg, C., Shi, Gang, Knowles J, Chen, Ming Huei, Zhu, H., van Duijn, C. M., Peltonen, L, Humphries, S.E., Kita, Y, Sidney S, Kao, W.H.L., Blankenberg, Stefan, Levy D, Cooper, Matthew N, Zhu, HD, Melander, Olle,, Peden, J. (John), Kumari, M. (Meena), Terzic, J., Whincup, PH, Swift, A.J., Ueshima, H. (Hirotsugu), Thorgeirsson, Gudmundur, Tayo, B., Sehmi, J. S., Demirkan, A., Bochud, Murielle, Doumatey, A, Nalls, Michael A., Humphries, Steve E, Parker, A.N. (Alex), Ebrahim, S., Hveem, K., Longstreth, W T, Kong, Augustine, Taylor KD, Mooser, Vincent, Uitterlinden, AG, Heckbert, Susan R, Orru, M., Gieger, C, Kumar, MV, Pichard, A.D., Harris, Tamara, Laaksonen, R., Levy, Daniel, Wiggins, K.L. (Kerri), Khaw, K-T. (Kay-Tee), Wichmann, H-Erich, Tobin, M.D. (Martin), Burnett, Mary Susan, Cooper, RS, Goel, Anuj, Wong, A., Dockrell, M., Watkins, H., Aspelund, T. (Thor), Thelle, Dag S., Vineis, Paolo, Schlessinger, D., Roberts R, Narisu, N., Lindsay, J.M., Platou, C.G.P., Chang, YPC, Andersen K, Ueshima, Hirotsugu, van Duijn, CM, Lee, J.Y., Nauck, M., Lawrence, R.W. (Robert), Bakker, Stephan J. L.; id_orcid, Langefeld, CD, Bots, Michiel L, Campbell, Harry; id_orcid, Longstreth jr., W. T., Wiggins, K.L., Kuznetsova, Tatiana, Meschia, JF, Ferrucci, L. (Luigi), Chasman, Daniel I, Kumar, M V Kranthi, Kolcic, I., Sõber, S, Singleton, Andrew, Ridker, P. M., Johnson, T., van Duijn, C., Salomaa, V, Sjögren, M, Kinra, S. (Sanjay), Hveem, K. (Kristian), Lumley T, Shuldiner, A.R., McKenzie, CA, Han, BG, Rudock, M.E., Paré, G., Soranzo, N. (Nicole), Seshadri, S., Platou, C.G., Hilton, G., Brown, MJ, Lagou, V., Halperin, E., Vineis, P. (Paolo), Wiggins, Kerri L, Province, M., Uda, Manuela, Ricceri, F. (Fulvio), Prokopenko, Inga, Marciante, K., Parker, Alex N., Harris T, O'Donnell CJ, Ikram, M Arfan, Felix, J. F., Snieder, H, Bergmann, Sven, Lawlor, Debbie A., Launer, Lenore J., Fox, C. S., Bergmann, S.M. (Sven), Wichmann, H. E., Loos, R.J.F. (Ruth), Wareham, N.J. (Nick), Adair, L.S., Hingorani, Aroon D., Rotimi, C. (Charles), Scuteri, A., König IR, Luan, Jian’an, Kleber, Marcus, Dreisbach, Albert W, Ueshima, H., Raffel, L.J. (Leslie), Rotter, Jerome I, Marmot, MG, Badola, S., Kuh, D., Hengstenberg C, Cambien, F., Dikkeschei, L. D., Goel, A., Bornstein, S.R. (Stefan), Thompson, John R., Walker, Max C., Risch N, Kim, H-L, Stojakovic, Tatjana, Hunt, Steven C, Terzic, Janos, Erdmann, J., Arora, Pankaj, Aulchenko, Y. S., Laitinen, J, Wagenknecht, Lynne E, Janipalli, CS, Chambers, J. C., Sjögren, Marketa, Fowkes, F.G., Raffel, L.J., Absher, Devin, van der Harst, Pim, Adeyemo, Adebowale, Perucha, E., Lucas, G. (Gavin), Palmer, Nicholette D., Sun, Yan V, Corsi, A.M., Schwarz, P.E., Tobin, Martin D, Jarinova O, Sun, Yan V., Artigas, Maria Soler, Nguyen, KD, Homuth, G., Maxwell, P. H., Dobnig, H., Onland-Moret, Charlotte N, Gretarsdottir, S., Jafar, T.H. (Tazeen), Uitterlinden, A. G., Sharma, P. (Pankaj), Mooser, V. (Vincent), Shaw-Hawkins, S. (Sue), Loley C, Koettgen, A, Guarrera, Simonetta, Wain, L.V. (Louise), Beckmann, J.S., Zgaga, L., Bolton, Judith A Hoffman, Stenvinkel, P., Kinra, Sanjay, Chambers, John C., Dahgam, S, Polasek, O., Lohman, Kurt K, Würtz, P., Kullo, I., Uitterlinden, A., Kumar, MV Kranthi, Brand, S-M, Kita, Yoshikuni, Morrison, Alanna, Collins, Francis S., Schunkert H, Iwai, N, Nalls, Michael A, Harris, TB, Wu, Y., Casas, Juan P., Deloukas, Panos, Pilz S, Ohkubo, Takayoshi, Harris, T., Shrine, Nick RG, Wareham, Nicholas J., Dahgam, S. (Santosh), O'Connell, J.R., Sim, X. (Xueling), Saleheen, D., Stewart, A.F., Arking, Dan E., Laitinen, Jaana, Brand, S.-M., Bakker, S. J., Abecasis, GR, Oostra, B.A. (Ben), Wang, TJ, Maria Corsi, Anna, Go, Min Jin, Kardia, Sharon L., Burtt, Noel, Ludwig, B, Zhao, J.H., Cooper, Jackie A, Vitart, V, Larson, M.G., Shaw-Hawkins, S, Fortmann S, Hayward, C, Waterworth DM, Mattace-Raso, F.U., Chen IY, Wang, X., Seelen, M. A., Gyllensten, U. (Ulf), Strachan, DP, Vasan, R.S., Böhm, Bernhard O., Lakatta, E. (Edward), Glazer, N.L., Kettunen, J, Cooper, R.S., Bornstein, Stefan R., Spector, TD, Vineis, P, Taylor, A. (Andrew), Tang, H., Wang, W., Tukiainen, Taru, Sehmi, Joban S., Milaneschi, Y., Wichmann, H. -Erich, Ferrucci, L., Nelson, Chris, Connell, JM, Hartikainen, A.L., Oostra, B. A., Hveem, Kristian, Bis, J. C., Forrester, T. (Terrence), Dahgam, Santosh, Munzel, T. F., Raffel, Leslie J., Denniff, Matthew, Lee, N.R. (Nanette), Isaacs, A, Zhu, XF, Tabara, Y, Peden, JF, Uda, M. (Manuela), Lehtimäki, T, Sim, Xueling, Strachan, David P, Shi, G., Mitchell, G. F., Tiret L, Guarrera, S., Abecasis, G.R. (Gonçalo), Winkler, Karl, Vasan, R. S., Spector, T. D., Radha Mani, K., Altshuler D, Samani, Nilesh J., Platou, CGP, Campbell, H, Bakker, Stephan J. L., Marciante K, Hofman, Bert, Wright, A. F., Nguyen, K.D., Gulcher, Jeffrey R., Burton, Paul R., Hunt, SC, Hercberg, S. (Serge), Watkins, H, Chang, YP, Bolton, Judith A. Hoffman, Ferrucci, Luigi, Zhu, X., Kardia, Sharon L, Kumar, M.V., Pichard, Augusto D., Spector, Tim D., Olden, M, Sijbrands, Eric J G, Olden, M., Gansevoort, R. T., Snieder, H., Wang, Xiaoling, Nitsch, D., Nicaud V, Arking, D.E. (Dan), Day, IN, Wichmann, H.-Erich, Shriner, D. (Daniel), Kleber M, Gaunt, TR, Ricceri, F., Khaw, K-T, Stark, K., Charlotte Onland-Moret, N., Meneton, Pierre, Khaw, K.-T., Smith, N. L., Hakonarson, Hakon H., Würtz, Peter, Gieger, C., Umemura, S. (Satoshi), Kleber, M., Pihur, Vasyl, Verwoert, G.C. (Germaine), Ridker, Paul M, Artigas, MS, Redfield, M. M., Lyytikäinen, LP, Elliott, P. (Paul), O'Donnell, Christopher J., Jarvelin, M-R, Wild, Philipp, Rice, K.M. (Kenneth), Lawlor, DA, Altshuler, D, Clarke, Robert, Miki, Tetsuro, Seielstad, M. (Mark), Hartikainen, Anna Liisa, Chambers, JC, Coresh, J. (Josef), Waterworth, D.M., Olden, M. (Matthias), Mangino, Massimo, Hicks, A.A. (Andrew), Verwoert, Germaine, Lucas, G, Hadley, D, Wild, S.H., Miki, T. (Tetsuro), Palmas, W. (Walter), Clarke, R., Rudock, Megan E., Sim, X, Fava, Cristiano, de Andrade, M., Mosley, TH, Swaminathan, R., Werdan, K., Hamsten, A. (Anders), Zhai, Guangju, Stefansson, K., Eiriksdottir, G., Würtz, P, Tiret, L., Johnson, AD, Siscovick, D., Wilde, S. +999 morecore +2 more sourcesChinese Expert Consensus on the Clinical Application of Finerenone in Geriatric Comorbidities
AGING MEDICINE, EarlyView.Mineralocorticoid receptor (MR) overactivation drives inflammation, oxidative stress, and fibrosis in the heart, kidneys, and vasculature, leading to cardiorenal dysfunction. MR signaling promotes hypertrophy, remodeling, and injury through pathways like oxidative stress and inflammation, resulting in vascular stiffness and progressive organ damage ...Xiaoming Wang, Cuntai Zhangwiley +1 more sourcePrioritization of Kidney Cell Types Highlights Myofibroblast Cells in Regulating Human Blood Pressure [PDF]
Introduction: Blood pressure (BP) is a highly heritable trait with over 2000 underlying genomic loci identified to date. Although the kidney plays a key role, little is known about specific cell types involved in the genetic regulation of BP.Methods ...de Borst, Martin, International Consortium of Blood Pressure; Soroush Sardari, de Borst, M, Koskinen, Seppo, Sardari, S, Vaez, A, International Consortium of Blood Pressure, de Borst, Martin; id_orcid, Snieder, H, Gow, Alan J.; id_orcid, Snieder, Harold, ?, ?, Kamali, Z, Ganji-Arjenaki, M, Ganji-Arjenaki, Mahboube, Snieder, Harold; id_orcid, Kamali, Zoha; id_orcid, Sardari, Soroush, Vaez, Ahmad, Vaez, Ahmac, et al., Kamali, Zoha +21 morecore +1 more sourceSmart Flexible Tactile Sensors: Recent Progress in Device Designs, Intelligent Algorithms, and Multidisciplinary Applications
Advanced Intelligent Discovery, EarlyView.Flexible tactile sensors have considerable potential for broad application in healthcare monitoring, human–machine interfaces, and bioinspired robotics. This review explores recent progress in device design, performance optimization, and intelligent applications. It highlights how AI algorithms enhance environmental adaptability and perception accuracy Siyuan Wang, Ming Dong, Rongrong Bao, Caofeng Pan +3 morewiley +1 more source
