Results 31 to 40 of about 17,773 (163)
HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto +13 more
wiley +1 more source
DESENVOLVER PARA PRESERVAR: O DESENVOLVIMENTISMO CONSERVADOR DE JUAREZ TÁVORA DURANTE A REPÚBLICA DE 1946 [PDF]
Resumo: Este artigo pretende tratar da percepção do conservador Juarez Távora sobre o conceito e a formulação de projetos para o desenvolvimento do Brasil na República de 1946.
Helio Cannone
doaj +1 more source
Abstract Employee resource groups (ERGs), also known as diversity networks or affinity groups, are becoming an increasingly important element of equality, diversity and inclusion (EDI) management in organizations. They are recognized as a potential voice mechanism for under‐represented employees and some studies highlight cases where ERGs have ...
Isabel Távora +2 more
wiley +1 more source
The Travel Drawings of Fernando Távora: a few Brief Notes on their Exhibition and Conservation
Fernando Távora was a renowned Portuguese architect who made significant contributions to the field of architecture, both in Portugal and internationally. He was known for his unique design style and his ability to seamlessly blend traditional and modern
Ana Freitas
doaj +1 more source
En este trabajo, realizado para la presentación del Trabajo de Fin de Grado de la Universidad de Sevilla en el Grado de Finanzas y Contabilidad, se abordará el tema de los paraísos fiscales.
Gamero Távora, Javier
core
Characteristics and identification of sites of chagasic ventricular tachycardia by endocardial mapping [PDF]
OBJECTIVE: To study electrophysiological characteristics that enable the identification and ablation of sites of chagasic tachycardia. METHODS: Thirty-one patients with chronic Chagas' heart disease and sustained ventricular tachycardia (SVT) underwent ...
De Paola, Angelo Amato Vincenzo +5 more
core +3 more sources
Financialisation and the (De‐)Unionisation of Workers in Portugal
ABSTRACT Over the last five decades, the degree of unionisation of workers has been decreasing and, therefore, by inadvertently accepting the deterioration of labour relations, the loss of labour rights, and the increase in the exploitation of labour all over the world, workers have not genuinely contested the neoliberal agenda and the deregulation and
Ricardo Barradas
wiley +1 more source
Àlvaro Siza and the Fragmented City [PDF]
In Álvaro Siza’s work, between 1970 and 1980, the presence of the ruin results from his quest for a methodology that allows the inclusion of the city’s past and its remains as an important starting point to embrace reality in its broadest sense.
Carlos Machado
doaj +1 more source
Abstract Academic research on economic issues from a gender approach remains limited, and similarly, few studies and academic papers have addressed the issue of the social and solidarity economy (SSE) from this perspective. The main objective of this paper is to contribute to the academic gap by completing an academic review on the subject and by ...
Artitzar Erauskin‐Tolosa +4 more
wiley +1 more source

