Results 71 to 80 of about 29,084 (194)

Staphylococcus aureus Augments Epithelial Skin Barrier Damage Through T Cell Activation in Cutaneous T Cell Lymphoma

open access: yesAllergy, EarlyView.
Staphylococcus aureus, commonly colonising CTCL patients, augments skin barrier dysfunction. Staphylococcal enterotoxins induce T‐cell release of barrier‐repressing cytokines (IL‐4, IL‐13, IL‐22, OSM). Cytokine signalling drives JAK‐dependent downregulation of filaggrin and loricrin in keratinocytes. Antibiotic‐mediated eradication of S. aureus induces
Maria Gluud   +23 more
wiley   +1 more source

Allergic Rhinitis and Its Impact on Asthma (ARIA)‐EAACI Guidelines—2024–2025 Revision: Part II—Guidelines on Oral and Ocular Treatments

open access: yesAllergy, EarlyView.
ABSTRACT Background Oral and ocular medications are frequently used in the treatment of allergic rhinitis (AR). As part of the update of the Allergic Rhinitis and its Impact on Asthma (ARIA)‐EAACI guidelines, this manuscript presents the ARIA‐EAACI 2024–2025 recommendations for oral and ocular treatments.
Rafael José Vieira   +230 more
wiley   +1 more source

Luteinizing hormone receptor knockout mouse: What has it taught us?

open access: yesAndrology, EarlyView.
Abstract Luteinizing hormone (LH), along with its agonist choriongonadotropin (hCG) in humans, is the key hormone responsible for the tropic regulation of the gonadal function. LH and hCG act through their cognate receptor, the luteinizing hormone/choriongonadotropin receptor (LHCGR; more appropriately LHR in rodents lacking CG), located in the testis ...
Ilpo T. Huhtaniemi
wiley   +1 more source

Targeted modulation of cell differentiation in distinct regions of the gastrointestinal tract via oral administration of differently PEG-PEI functionalized mesoporous silica nanoparticles

open access: yesInternational Journal of Nanomedicine, 2016
Diti Desai,1–4 Neeraj Prabhakar,2 Veronika Mamaeva,3,5 Didem Şen Karaman,2,4 Iris AK Lähdeniemi,1,6 Cecilia Sahlgren,3,7,* Jessica M Rosenholm,2,4,* Diana M Toivola1,6,* 1Cell Biology, Faculty of Science and Engineering, Åbo Akademi ...
Desai D   +7 more
doaj  

Missed Care from the Patient’s Perspective – A Scoping Review

open access: yesPatient Preference and Adherence, 2020
Noora Gustafsson, 1 Helena Leino-Kilpi, 1, 2 Ivana Prga, 3 Riitta Suhonen, 1, 2, 4 Minna Stolt 1, 2 On behalf of the RANCARE consortium COST Action – CA15208 1Department of Nursing Science, University of Turku, Turku, Finland; 2Turku University ...
Gustafsson N   +4 more
doaj  

Randomized, single‐centre, double‐blinded repeated dose investigation of safety and tolerability of ocular administrations of a novel silica eye drop product in healthy volunteers

open access: yesActa Ophthalmologica, EarlyView.
Abstract Purpose Managing ocular diseases often requires frequent eye drop administration, which can challenge patient compliance. A long‐acting eye drop technology using an amorphous synthetic silica composite was developed to address this. Our study aimed to assess the safety and tolerability of the Silica Eye Drop platform in healthy volunteers over
Aleksandra Poluianova   +5 more
wiley   +1 more source

Intestinal Atresia in Finland: Maternal Risk Factors, Prevalence, Associated Anomalies and Survival

open access: yesActa Paediatrica, EarlyView.
ABSTRACT Aim We aimed to investigate prevalence, associated anomalies and survival of congenital intestinal atresia and to examine maternal risk factors for jejunoileal atresia (JIA). Methods All children born with, or pregnancies terminated because of, JIA or colonic atresia (CA) in Finland during 1987–2019 were identified from the Finnish Register of
Esko Tahkola   +9 more
wiley   +1 more source

Beyond performance: Emotions before and after semi‐high‐stakes mathematics testing among school‐aged students

open access: yesBritish Journal of Educational Psychology, EarlyView.
Abstract Background Previous research has shown that testing differs significantly from other classroom activities and is associated with heightened negative emotions and lower levels of positive emotions. However, relatively little is known about students' emotions surrounding testing, particularly in higher‐stakes assessment settings. Aims This study
Reetta Kyynäräinen   +5 more
wiley   +1 more source

Revised classification of glaciofluvial landforms in the Finnish sector of the Fennoscandian Ice Sheet

open access: yesBoreas, EarlyView.
Effective and sustainable land use, conservation, and the use of geological resources (incl. raw materials, aggregates and groundwater) require a clear classification system of sedimentary units, with well‐defined vocabulary and unified mapping practices.
Jussi Hovikoski   +6 more
wiley   +1 more source

Parents With Substance Use Disorder in the Holding Tight Treatment System: Intervention Effectiveness and Moderating Effects

open access: yesChild &Family Social Work, EarlyView.
ABSTRACT Parents with substance use disorder have multiple risks affecting their parenting. Mental health problems and adverse childhood experiences (ACEs) with problems in emotion regulation and adult attachment insecurity may impair the early interaction with the infant.
Saara J. Salo   +4 more
wiley   +1 more source

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