Results 31 to 40 of about 110,014 (228)
Pediatric Blood &Cancer, EarlyView.ABSTRACT Although most malignant germ cell tumors (GCTs) are highly curable with cisplatin‐based therapy, options for patients with multiply relapsed/refractory disease remain limited. For this population, we report the first pediatric use of gemcitabine, docetaxel, melphalan, and carboplatin (GemDMC) as part of sequential cycles of high‐dose ...
Maria Frost +10 more
wiley +1 more source
The problems during choice of profession and comparison of these problems with anxiety and depression in final year of high school students [PDF]
, 2014 Objective: We aimed to investigate the relationship between prevalence of anxiety, depressive disorder symptoms and some sociodemographic variables in the final year of high-school students, secondly to determine the socio-economic and cultural factors ...
Hüseyin Avni Şahin +6 more
core +1 more source
Mapping the evolution of mitochondrial complex I through structural variation
FEBS Letters, EarlyView.Respiratory complex I (CI) is crucial for bioenergetic metabolism in many prokaryotes and eukaryotes. It is composed of a conserved set of core subunits and additional accessory subunits that vary depending on the organism. Here, we categorize CI subunits from available structures to map the evolution of CI across eukaryotes. Respiratory complex I (CI)
Dong‐Woo Shin +2 more
wiley +1 more source
Clinical and demographic characteristics of 165 patients with lichen planus [PDF]
, 2014 Objective: Lichen planus (LP), is a papulosquamous inflammatory disease, which involves the skin, mucous membranes, nails and scalp. The incidence varies according to geographical regions.
Asena Çiğdem Doğramacı +4 more
core +1 more source
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
MODERN TIPTA ÖLÜMÜN NELİĞİ ÜZERİNE
Felsefe Dünyası, 2020 Modern tıbbın ölümü tasvir etme tarzı ile bunun beraberinde getirdiği tıbbî ve felsefi sorunların ortaya konulması, bu sorunların analiz edilip eleştirilmesi büyük bir önem taşımaktadır.
Şahin Efil
doaj
In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS
FEBS Letters, EarlyView.We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka +11 more
wiley +1 more source
Bonesetter choice of Turkish society in musculoskeletal injuries and the affecting factors [PDF]
, 2013 Objective: In this study, it was aimed to investigate the demographic features, administration reasons and educational status of the patients who were presented to the bonesetters for orthopedic complaints.
Ahmet Aslan +4 more
core +1 more source
Calpain small subunit homodimerization is robust and calcium‐independent
FEBS Letters, EarlyView.Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
Kültürel Antropolojik Okuma Yaklaşımıyla Râzî Tefsirinde Tıp
Kocaeli İlahiyat Dergisi, 2021 Her eserde, onun müellifinden izler bulunması doğaldır. Bu izlerin bir tefsir eserinden takip edilmesi, eserde ilahî hitap ile insanî hitabın birlikte bulunmasından ötürü dikkat çekici ve önemlidir.
Hatice Avcı
doaj