Results 71 to 80 of about 921 (215)

T-2 toxin-induced spatial learning and memory impairment in mice via the gut-brain axis and the intervening effects of resveratrol

Ecotoxicology and Environmental Safety
T-2 toxin, classified as a mycotoxin, harms immune and cognitive systems. Recently, an increasing number of studies have focused on the neurotoxic effects of T-2 toxin. However, there is still a need for a better understanding of the molecular mechanisms
Sheng-Quan Su, Gui-Yuan Xiong, Chun-Yan Yao, Xiao-Ling Liu, Yin-Yin Xia, Jin-Yun Long, Xiu-Kuan Li, Liang-Mei Wang, Long Yi, Wu-Wei Xu, Wu-Qiang Lu, Qian-Qian Li, Ting Hu, Hao Liu, Ke-Xue Wang, Peng Luo, Tong-Jian Cai   +16 more
doaj   +1 more source

Infant Embryonal CNS Tumors: Molecular Insights and Treatment Considerations for Contemporary Pediatric Neuro‐Oncology

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Embryonal tumors comprise the majority of malignant central nervous system (CNS) neoplasms diagnosed in children under 3 years of age. Compared with their counterparts in older children, these tumors exhibit distinct molecular biology and a more aggressive clinical phenotype, while their management is complicated by the heightened ...
Sudarshawn Damodharan, Mariah Wright‐Nadkarni, Mohamed S. Abdelbaki, Girish Dhall   +3 more
wiley   +1 more source

Effect of T-2 Toxin in Combination with Vitamin E, Selenium and Mycotoxin Binder on Lipid Peroxide Status and on the Glutathione Redox System in Broiler Chicken

The Journal of Poultry Science, 2006
The effect of T-2 toxin (2.35mg/kg of feed) on lipid peroxidation and on the antioxidant defence system was studied in blood plasma, red blood cells (RBC), liver and spleen of broiler chickens. The influences of antioxidant vitamin E (10.5mg/animal/day)+
Mária Weber, Krisztián Balogh, Márta Erdélyi, Miklós Mézes   +3 more
doaj   +1 more source

Tibial Damage Caused by T-2 Toxin in Goslings: Bone Dysplasia, Poor Bone Quality, Hindered Chondrocyte Differentiation, and Imbalanced Bone Metabolism

Animals
T-2 toxin, the most toxic type A trichothecene, is widely present in grain and animal feed, causing growth retardation and tissue damage in poultry. Geese are more sensitive to T-2 toxin than chickens and ducks.
Wang Gu, Lie Hou, Qiang Bao, Qi Xu, Guohong Chen   +4 more
doaj   +1 more source

A Bibliometric Analysis of Publications in Uremic Toxins From 1991 to 2024

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Uremic toxins are a growing area of research in nephrology, with significant implications in the progression and treatment of chronic kidney disease (CKD) and the management of end‐stage kidney disease (ESKD). This bibliometric analysis aims to evaluate the global research trends, key contributors, and the impact of publications in ...
Yuh‐Shan Ho, Karim M. Soliman, Wisit Cheungpasitporn, Wannasit Wathanavasin, Ahmed Daoud, Ahmed I. Kamal, Balázs Szamosfalvi, Tibor Fülöp   +7 more
wiley   +1 more source

Betulinic Acid Ameliorates T-2 Toxin-Induced Neuroinflammation by Suppressing Oxidative Stress via Regulating Nrf2/NLRP3 Axis

Veterinary Sciences
T-2 toxin is widely present in agricultural products and poses a significant neurotoxicity threat. Betulinic acid (BA), a natural triterpenoid, exhibits strong antioxidant and anti-inflammatory properties.
Jiao Wu, Hongyi Ding, Jiayu He, Zhaoping Ou, Ziming Wang, Wenyu Ba, Quanwei Li, Yunqiu Yan, Jiaming Wang, Jine Yi, You Huang   +10 more
doaj   +1 more source

Photocatalytic Degradation of T-2 Toxin by Zinc Oxide Nanoparticles [PDF]

Shipin Kexue
In this study, ZnO nanoparticles with high crystallinity and good dispersibility for efficient and green photocatalytic degradation of T-2 toxin were successfully prepared by a green and mild solvent hydrothermal method.
LOU Xiuping, HUANG Qingwen, GUO Wenbo, LIU Xiaojin, WANG Xinyi, NIE Dongxia, HAN Zheng
doaj   +1 more source

Comparative Evaluation of Hemodiafiltration, Hemoperfusion, and Standard Hemodialysis on Efficacy, Inflammatory Control, Dialysis Adequacy, and Safety in End‐Stage Renal Disease: A Prospective Observational Study

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Chronic micro‐inflammation in patients with end‐stage renal disease (ESRD) is a significant driver of cardiovascular complications and diminished quality of life. While standard hemodialysis (SHD) effectively manages small‐molecule clearance, its ability to remove medium‐to‐large uremic toxins—the primary catalysts of systemic ...
Hongwei Zuo, Weisi Dai, Jie Mao, Mei Ye, Xingshan Lu, Xiaocui Zhang   +5 more
wiley   +1 more source

Toxicokinetics of T-2 Toxin, HT-2 Toxin and T-2 Triol after Intravenously Administrated T-2 Toxin in Swine [PDF]

Journal of Animal and Veterinary Advances, 2012
Yong-Xue Sun, Hai-Yan Zhao, Yu-Jing Liu, Zhen-Qing Dai, Bing-Hu Fang   +4 more
openaire   +1 more source

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source