Results 1 to 10 of about 2,269,258 (384)

Spectrum of mutational signatures in T-cell lymphoma reveals a key role for UV radiation in cutaneous T-cell lymphoma

Scientific Reports, 2021
T-cell non-Hodgkin’s lymphomas develop following transformation of tissue resident T-cells. We performed a meta-analysis of whole exome sequencing data from 403 patients with eight subtypes of T-cell non-Hodgkin’s lymphoma to identify mutational ...
Christine L. Jones, Andrea Degasperi, Vieri Grandi, Tauanne D. Amarante, Genomics England Research Consortium, Tracey J. Mitchell, Serena Nik-Zainal, Sean J. Whittaker   +7 more
doaj   +2 more sources

B-cell lymphomas morphologically resembling T-cell lymphomas [PDF]

Cancer, 1985
Seven cases of B-cell lymphoma that morphologically resembled T-cell lymphoma are described. These cases are of four morphologic types: atypical poorly differentiated lymphocytic lymphoma (PDLL) with convoluted nuclei, "Lennert's" lymphoma, mixed lymphocytic-"histiocytic" lymphoma with large variation in size of abnormal cells, and "histiocytic ...
Ila Mirchandani, Margarita Palutke, Pamela Tabaczka, Steven Goldfarb, Leopoldo Eisenberg, M. S. Y. Pak   +5 more
openalex   +4 more sources

Detection and isolation of type C retrovirus particles from fresh and cultured lymphocytes of a patient with cutaneous T-cell lymphoma [PDF]

Proceedings of the National Academy of Sciences of the United States of America, 1980
Bernard J. Poiesz, Francis W. Ruscetti, Adi F. Gazdar, Paul A. Bunn, John D. Minna, Robert C. Gallo   +5 more
openalex   +2 more sources

Morphological characterization of canine retrobulbar lymphoma [PDF]

Open Veterinary Journal, 2018
This report characterized seven cases of canine retrobulbar lymphoma that have been diagnosed during 2008 to 2014 by immunophenotyping of CD3 and Pax5. Classification of lymphoma were performed according to the revised WHO guidelines.
Natthanet Sritrakoon, Kannika Siripattarapravat, Phudit Maneesaay, Chidozie J. Amuzie, Aree Thayananuphat   +4 more
doaj   +1 more source

Epcoritamab, a Novel, Subcutaneous CD3xCD20 Bispecific T-Cell–Engaging Antibody, in Relapsed or Refractory Large B-Cell Lymphoma: Dose Expansion in a Phase I/II Trial

Journal of Clinical Oncology, 2022
PURPOSE Epcoritamab is a subcutaneously administered CD3xCD20 T-cell–engaging, bispecific antibody that activates T cells, directing them to kill malignant CD20+ B cells.
C. Thieblemont, T. Phillips, H. Ghesquières, C. Cheah, M. Clausen, D. Cunningham, Y. Do, T. Feldman, R. Gasiorowski, W. Jurczak, Tae Min Kim, D. Lewis, M. van der Poel, M. Poon, Mariana Cota Stirner, N. Kilavuz, Christopher W Chiu, Meng‐Yu Chen, M. Sacchi, B. Elliott, T. Ahmadi, M. Hutchings, P. Lugtenburg   +22 more
semanticscholar   +1 more source

Glofitamab, a Novel, Bivalent CD20-Targeting T-Cell–Engaging Bispecific Antibody, Induces Durable Complete Remissions in Relapsed or Refractory B-Cell Lymphoma: A Phase I Trial

Journal of Clinical Oncology, 2021
PURPOSE Glofitamab is a T-cell–engaging bispecific antibody possessing a novel 2:1 structure with bivalency for CD20 on B cells and monovalency for CD3 on T cells. This phase I study evaluated glofitamab in relapsed or refractory (R/R) B-cell non-Hodgkin
M. Hutchings, F. Morschhauser, G. Iacoboni, C. Carlo-Stella, F. Offner, A. Sureda, G. Salles, J. Martínez-López, M. Crump, D. Thomas, P. N. Morcos, C. Ferlini, Ann-Marie E. Bröske, A. Belousov, M. Bacac, N. Dimier, D. Carlile, L. Lundberg, D. Pérez-Callejo, P. Umaña, T. Moore, M. Weisser, M. Dickinson   +22 more
semanticscholar   +1 more source

Peripheral T-Cell Lymphomas of the T Follicular Helper Type: Clinical, Pathological, and Genetic Attributes

Hemato, 2022
Follicular helper T-cell (TFH) lymphomas comprise a unique group of T-cell lymphomas that represent neoplastic proliferations of follicular helper T-cells and share genetic, immunophenotypic, morphologic, and clinical features.
Karthik A. Ganapathi, Kristin H. Karner, Madhu P. Menon   +2 more
doaj   +1 more source

NK-/T-cell lymphomas [PDF]

Leukemia, 2021
AbstractNatural killer/T-cell lymphoma (NKTL) is a sub-type of Epstein–Barr virus (EBV)-related non-Hodgkin lymphomas common in Asia and Latin America but rare elsewhere. Its pathogenesis is complex and incompletely understood. Lymphoma cells are transformed from NK- or T-cells, sometimes both.
Hua Wang, Bi-bo Fu, Robert Peter Gale, Yang Liang   +3 more
openaire   +3 more sources

KTE-X19 CAR T-Cell Therapy in Relapsed or Refractory Mantle-Cell Lymphoma.

New England Journal of Medicine, 2020
BACKGROUND Patients with relapsed or refractory mantle-cell lymphoma who have disease progression during or after the receipt of Bruton's tyrosine kinase (BTK) inhibitor therapy have a poor prognosis. KTE-X19, an anti-CD19 chimeric antigen receptor (CAR)
Michael L. Wang, J. Muñoz, A. Goy, F. Locke, C. Jacobson, B. Hill, J. Timmerman, H. Holmes, S. Jaglowski, I. Flinn, P. Mcsweeney, D. Miklos, J. Pagel, M. Kersten, N. Milpied, H. Fung, M. Topp, R. Houot, A. Beitinjaneh, W. Peng, Lianqing Zheng, J. Rossi, R. Jain, A. Rao, P. Reagan   +24 more
semanticscholar   +1 more source

HLA-DR Helps to Differentiate Erythrodermic Cutaneous T-cell Lymphoma from Erythrodermic Inflammatory Dermatoses in Flow Cytometry

Acta Dermato-Venereologica, 2023
Differential diagnosis of erythroderma is challenging in dermatology, especially in differentiating erythrodermic cutaneous T-cell lymphoma from erythrodermic inflammatory dermatoses.
Jingru Sun, Ran You, Beini Lyu, Xueying Li, Yumei Gao, Yujie Wen, Chenxue Qu, Yang Wang   +7 more
doaj   +1 more source