Results 91 to 100 of about 2,269,258 (384)

Targeting histone deacetylases in T-cell lymphoma

Leukemia and Lymphoma, 2017
Histone deacetylase inhibitors (HDACi) are epigenetic modifiers with single-agent activity in patients with cutaneous and peripheral T-cell lymphoma (CTCL, PTCL).
A. Moskowitz, S. Horwitz
semanticscholar   +1 more source

Subcutaneous T-cell lymphoma

Dermatology Online Journal, 2003
A 70-year-old woman presents with a 2-year history of intermittent, subcutaneous nodules. The patient was otherwise asymptomatic. A biopsy specimen was consistent with a subcutaneous T-cell lymphoma, a rare subset of peripheral T-cell lymphoma; when accompanied by the hemocphagocytic syndrome, it can be rapidly fatal.
openaire   +5 more sources

Az érett T-sejtes lymphomák funkcionális patogenezise = Functional pathogenesis of mature T-cell lymphomas [PDF]

, 2008
A világon az elsők között állapítottuk meg, hogy az angioimmunoblastos T-sejtes lymphoma daganatsejtjei az aktivált follicularis B helper T-sejtek (TFH) immunfenotípusát mutatják.
Bagdi, Enikő, Krenács, László
core  

T-Lineage Lymphoblastic Lymphoma and Leukemia—a MASSive Problem [PDF]

, 2010
T cell precursor malignancies may present as T-lymphoblastic lymphoma (T-LBL) with marked enlargement of lymph nodes or acute T-lymphoblastic leukemia (T-ALL) with little lymph node enlargement. In this issue of Cancer Cell, Feng et al.
Mullighan, Charles G.
core   +1 more source

Escape from TGF‐β‐induced senescence promotes aggressive hallmarks in epithelial hepatocellular carcinoma cells

Molecular Oncology, EarlyView.
Chronic TGF‐β exposure drives epithelial HCC cells from a senescent state to a TGF‐β resistant mesenchymal phenotype. This transition is characterized by the loss of Smad3‐mediated signaling, escape from senescence, enhanced invasiveness and metastatic potential, and upregulation of key resistance modulators such as MARK1 and GRM8, ultimately promoting
Minenur Kalyoncu, Dilara Demirci, Sude Eris, Bengisu Dayanc, Ece Cakiroglu, Merve Basol, Merve Uysal, Gulcin Cakan‐Akdogan, Fang Liu, Mehmet Ozturk, Gökhan Karakülah, Serif Senturk   +11 more
wiley   +1 more source

Distinct morphologic, phenotypic, and clinical-course characteristics of indolent peripheral T-cell lymphoma [PDF]

, 2013
Peripheral T-cell lymphoma, not otherwise specified (PTCL-NOS) consists of a heterogeneous group of lymphomas. Patients. generally show an aggressive clinical course and very poor outcome.
Asano, Carbone, Cossman, Du, Eiko Hayashi, Gallamini, Jaffe, Katsuyoshi Takata, Lamia Abd Alkader, Louissaint, Lymphoma Study Group of Japanese Pathologists, Mannami, Matsumoto, Midori Ando, Mitsune Tanimoto, Mitsuyoshi Hirokawa, Mohrmann, Perry, Qin, Rahemtullah, Rizvi, Sallusto, Sato, Sato, Sato, Seiko Sawada-Kitamura, Shun Sugiguchi, Soichiro Nose, Swerdlow, Tadashi Yoshino, The International Non-Hodgkin's Lymphoma Prognostic Factors Project, van Dongen, Vose, Weisenburger, Went, Xiao, Yao, Yasuharu Sato, Yasushi Hiramatsu, Yokose, Yoshinobu Maeda, Yoshiro Tachiyama, Yukie Tashiro   +42 more
core   +1 more source

ShcD adaptor protein drives invasion of triple negative breast cancer cells by aberrant activation of EGFR signaling

Molecular Oncology, EarlyView.
We identified adaptor protein ShcD as upregulated in triple‐negative breast cancer and found its expression to be correlated with reduced patient survival and increased invasion in cell models. Using a proteomic screen, we identified novel ShcD binding partners involved in EGFR signaling pathways.
Hayley R. Lau, Hayley S. Smith, Begüm Alural, Claire E. Martin, Laura A. New, Manali Tilak, Sara L. Banerjee, Hannah N. Robeson, Nicolas Bisson, Anne‐Claude Gingras, Jasmin Lalonde, Nina Jones   +11 more
wiley   +1 more source

T-Cell Lymphoma of the Thyroid Gland in Celiac Disease

Canadian Journal of Gastroenterology, 2000
Previous studies have reported the association between celiac disease and T cell lymphoma of the intestine as well as hepatosplenic lymphoma, a specialized peripheral type of T cell lymphoma.
Hugh J Freeman
doaj   +1 more source

T-Cell Lymphomas Presenting as Colon Ulcers and Eosinophilia

Case Reports in Gastroenterology, 2015
Primary gastrointestinal T-cell lymphoma is an uncommon entity and primary colon T-cell lymphoma is even rarer. The majority of enteropathy-associated T-cell lymphomas present predominantly as ulcers or strictures in the endoscopic examinations, while ...
Ping-Hsiu Wu, Kuang-En Chu, Yu-Min Lin, Shu-Han Huang, Chin-Chu Wu   +4 more
doaj   +1 more source

Romidepsin in the treatment of cutaneous T-cell lymphoma

Journal of Blood Medicine, 2011
The most common subtypes of primary cutaneous T-cell lymphoma (CTCL) are mycosis fungoides and Sézary syndrome. Clinical manifestations and prognosis in CTCL are highly variable. Improving the management of this incurable disease with limited toxicity is
Salvia Jain, Jasmine Zain
semanticscholar   +1 more source