Results 21 to 30 of about 2,045,259 (260)

Genome-wide DNA methylation profiles indicate CD8+ T cell hypermethylation in multiple sclerosis. [PDF]

open access: yesPLoS ONE, 2015
Determine whether MS-specific DNA methylation profiles can be identified in whole blood or purified immune cells from untreated MS patients.Whole blood, CD4+ and CD8+ T cell DNA from 16 female, treatment naïve MS patients and 14 matched controls was ...
Steffan D Bos   +11 more
doaj   +1 more source

Structural insights into DNA repair by RNase T--an exonuclease processing 3' end of structured DNA in repair pathways.

open access: yesPLoS Biology, 2014
DNA repair mechanisms are essential for preservation of genome integrity. However, it is not clear how DNA are selected and processed at broken ends by exonucleases during repair pathways.
Yu-Yuan Hsiao   +4 more
doaj   +1 more source

Determination of the T-DNA Transfer and the T-DNA Integration Frequencies upon Cocultivation of Arabidopsis thaliana Root Explants

open access: yesMolecular Plant-Microbe Interactions, 2000
Using the Cre/lox recombination system, we analyzed the extent to which T-DNA transfer to the plant cell and T-DNA integration into the plant genome determine the transformation and cotransformation frequencies of Arabidopsis root cells.
Sylvie De Buck   +3 more
doaj   +1 more source

Callogenesis in root explants of four species of the family Solanaceae after inducing by Agrobacterium rhizogenes [PDF]

open access: yesZīst/shināsī-i Giyāhī-i Īrān, 2015
Studying explants affected by Agrobacterium rhizogenes shows that in addition to possible formation of hairy roots, it is likely that callogenesis can be induced in these tissues. The T-DNA region of A.
Zahra Shakeran, Mehrnaz Keyhanfar
doaj  

Topological DNA damage, telomere attrition and T cell senescence during chronic viral infections

open access: yesImmunity & Ageing, 2019
Background T cells play a key role in controlling viral infections; however, the underlying mechanisms regulating their functions during human viral infections remain incompletely understood.
Yingjie Ji   +15 more
doaj   +1 more source

Recombination between T-DNA insertions to cause chromosomal deletions in Arabidopsis is a rare phenomenon [PDF]

open access: yesPeerJ, 2018
We previously described the identification of a chromosomal deletion in Arabidopsis thaliana that resulted in the elimination of genomic DNA between two T-DNA insertions located ca. 25 kilobases apart on chromosome IV.
John F. Seagrist   +2 more
doaj   +2 more sources

Identifikasi Thrips alliorum (Priesner), Thrips hawaiiensis (Morgan), dan Thrips parvispinus (Karny) berdasarkan variasi DNA COI mitokondria

open access: yesJurnal Entomologi Indonesia, 2017
Thrips is the second largest genus on the order of Thysanoptera, most of them are polyphagous and some species are serious pests on vegetables. The damages caused by thrips can reach 30–50% yield loss. Thrips alliorum (Priesner), T. hawaiiensis (Morgan),
Nia Kurniawaty   +2 more
doaj   +1 more source

Characterization of Genomic Integration and Transgene Organization in Six Transgenic Rapeseed Events

open access: yesJournal of Integrative Agriculture, 2014
To characterize the DNA rearrangement of both the T-DNA region and the genomic insertion site during T-DNA insertion, the Genomewalker strategy was used to isolate the junctions between the inserted DNA and the plant genomic DNA in six rapeseed events as
Yu-hua WU   +4 more
doaj   +1 more source

STING Is Required in Conventional Dendritic Cells for DNA Vaccine Induction of Type I T Helper Cell- Dependent Antibody Responses

open access: yesFrontiers in Immunology, 2022
DNA vaccines elicit antibody, T helper cell responses and CD8+ T cell responses. Currently, little is known about the mechanism that DNA vaccines employ to induce adaptive immune responses.
Justin Theophilus Ulrich-Lewis   +9 more
doaj   +1 more source

Molecular Genetics Using T-DNA in Rice [PDF]

open access: yesPlant and Cell Physiology, 2005
Now that sequencing of the rice genome is nearly completed, functional analysis of its large number of genes is the next challenge. Because rice is easy to transform, T-DNA has been used successfully to generate insertional mutant lines. Collectively, several laboratories throughout the world have established at least 200,000 T-DNA insertional lines ...
An, GH, Lee, S, Kim, SH, Kim, SR
openaire   +3 more sources

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