Results 41 to 50 of about 10,843,040 (254)

Paclitaxel induces NM2‐dependent cellular contraction through GEF‐H1 dissociation from microtubules and RhoA/ROCK activation in cancer cells

open access: yesMolecular Oncology, EarlyView.
Taxanes are widely used chemotherapeutics whose effects on cellular mechanics remain poorly understood. We show that paclitaxel induces rapid cellular contraction by promoting GEF‐H1 dissociation from microtubules and non‐muscle myosin II activation through RhoA/ROCK.
Gloria Asensio‐Juárez   +5 more
wiley   +1 more source

Fluid flow in T-junction of pipes [PDF]

open access: yes, 2007
The aim of this work is to study flow properties at T-junction of pipe, pressure loss suffered by the flow after passing through T-junction and to study reliability of the classical engineering formulas used to find head loss for T-junction of pipes.
Paritosh, Vasava
core   +1 more source

SPHINX31 acts as a SRPK1 inhibitor targeting the ATR/DNA‐PKcs/CHK1 replicative checkpoint to inhibit cell growth in non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
The kinase SRPK1 directly interacts with the protein TOPBP1 and regulates the pre‐mRNA splicing of WIZ thereby contributing to the activation of the ATR/CHK1 replicative checkpoint in response to replicative stress. This allows cancer cells' genomic stability and survival.
Amani Shreim   +17 more
wiley   +1 more source

Oviform Pipe Test

open access: yes, 2023
This record was harvested from a previous catalogue system and will be withdrawn in 2025. Information in this record may be superseded or incomplete. Visit this record in UMA's new catalogue at: https://archives.library.unimelb.edu.au/nodes/view/207760 ...
Reinforced Concrete and Monier Pipe Construction Co. Pty Ltd
core   +3 more sources

Numerical Simulation of Flow Field in T-junction Separator of Produced Liquid with High Water Content

open access: yesShiyou jixie, 2021
T-junction separator has the characteristics of simple structure, no moving parts, easy design and installation, less maintenance, low operating cost, low energy consumption and small footprint.
Tian Yangyang   +4 more
doaj  

Structural modelling and testing of failed high energy pipe runs: 2D and 3D pipe whip [PDF]

open access: yes, 2011
Copyright @ 2011 ElsevierThe sudden rupture of a high energy piping system is a safety-related issue and has been the subject of extensive study and discussed in several industrial reports (e.g. [2], [3] and [4]).
B. Wang   +5 more
core   +1 more source

Adaptive Foam 3D Printing of Ultralight and Multifunctional Materials

open access: yesAdvanced Engineering Materials, EarlyView.
Adaptive foam 3D printing, enabled by expandable microspheres, imparts cellular structures to thermoplastic and thermosetting polymers, manufactured through a variety of processes including fused filament fabrication, direct ink writing, digital light processing, and inkjet printing.
Nariman Rajabifar, Amir Ameli
wiley   +1 more source

Numerical and Experimental Study of Turbulent Mixing Characteristics in a T-Junction System

open access: yesApplied Sciences, 2020
The mixing, migration, and degradation of pollutants in sewers are the main causes for pipeline corrosion and the increased pollution scope. The clarification of the turbulent mixing characteristics in pipelines is critical for finding the source of ...
Bin Sun   +5 more
doaj   +1 more source

Fluid flow and heat transfer in a dual-wet micro heat pipe [PDF]

open access: yes, 2007
Micro heat pipes have been used to cool micro electronic devices, but their heat transfer coefficients are low compared with those of conventional heat pipes. In this work, a dual-wet pipe is proposed as a model to study heat transfer in micro heat pipes.
Watson, S.J., Wong, H., Zhang, J.
core   +1 more source

Silicone Breast Implants as a Model System for Understanding Polymer Permeation in Soft Materials In Vivo

open access: yesAdvanced Healthcare Materials, EarlyView.
Silicone breast implants are presented as a model system for understanding polymer permeation in vivo. Rather than representing material failure, “gel bleed” emerges from solution–diffusion transport‐mediated. By integrating polymer architecture, physicochemical transport, and biointerfacial processes, this review provides a unified framework that ...
D. Bouyer   +12 more
wiley   +1 more source

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