Results 61 to 70 of about 10,843,040 (254)
Harnessing Phase Separation for the Development of High‐Performance Hydrogels
Advanced Science, EarlyView.ABSTRACT Hydrogels are indispensable for the development of next‐generation bioelectronics, soft robotics, and biomedical devices, where their mechanical properties determine performance and reliability. Among strategies to enhance hydrogel mechanics, phase separation enables controlled heterogeneity resulting in gel networks that are reinforced by ...
Yue Shao +3 more
wiley +1 more source
Numerical simulation of thermal stress fluctuation at a mixing tee for thermal fatigue problems
Mechanical Engineering Journal, 2018 Thermal fatigue cracks have been found at mixing tees in nuclear power plants. The mixing flow of high and low temperature fluids causes temperature and stress fluctuations in the pipe wall and these result in fatigue crack initiation.
Koji MIYOSHI +3 more
doaj +1 more source
Advanced Science, EarlyView.The membrane‐active peptide Pep19‐2.5 reduces harmful inflammation by blocking activation of the NLRP3 inflammasome at trans‐Golgi network membranes. By targeting key membrane interactions, Pep19‐2.5 suppresses inflammatory IL‐1β production and alleviates allergic airway inflammation in mice, leading to reduced immune cell infiltration and improved ...
Jonas Engelhardt +16 more
wiley +1 more source
Manufacturing of 42SiCr-Pipes for Quenching and Partitioning by Longitudinal HFI-Welding
Metals, 2019 In the pipe manufacturing and pipe processing industry, the demand for cost-effective pipes with high strength and good ductility is increasing.
Martin Kroll +4 more
doaj +1 more source
Advanced Science, EarlyView.The iLEAP technique integrates high‐throughput two‐photon lithography with extrusion printing, bridging sub‐micrometer precision and macroscopic scaffold fabrication. By employing a low‐exothermic photoinitiator, it mitigates thermal damage to biopolymers and preserves bioactivity.
Qifeng Guan +11 more
wiley +1 more source
A Small‐Molecule DEPTAC Rescues Cognitive Deficits by Targeted Dephosphorylation of Pathological Tau
Advanced Science, EarlyView.TP2 is a fully synthetic small‐molecule dephosphorylation‐targeting chimera that recruits endogenous PP2A‐Bα to Tau, enabling targeted removal of pathological phosphate modifications. In two tauopathy mouse models, systemic TP2 reduces Tau pathology, preserves neuronal and synaptic integrity, improves neuroimmune homeostasis, and rescues cognition ...
Fei Sun +12 more
wiley +1 more source
China's Low‐Carbon Energy Transition Over the Past Two Decades: Experiences and Implications
Advanced Science, EarlyView.China's low‐carbon energy transition features a brief decline and subsequent rebound in coal consumption, alongside the rapid expansion of renewable energy. This study develops a stage‐based analytical framework to explain this evolution from the perspectives of economic development, energy security, and environmental sustainability, revealing how ...
Yu Liu +3 more
wiley +1 more source
Angewandte Chemie, EarlyView.Cationic titanium sandwich catalysts display exceptional activity in the hydrodefluorination of Csp3─F bonds, in the presence of silanes and aromatic solvents (turnover numbers up to 3000). As a result, they can be used to defluorinate challenging fluoropolymers, such as poly(vinyl fluoride) (PVF) or poly(vinylidene fluoride) (PVDF).
Louis Le Moigne +9 more
wiley +2 more sources
TECTB Variants Reveal Tectorial Membrane Vulnerability in Dominant Non‐Syndromic Hearing Loss
Advanced Science, EarlyView.TECTB is a non‐collagenous protein of the tectorial membrane – an extracellular matrix of the cochlea. This study identifies dominant missense variants in TECTB linked to human hereditary deafness in two unrelated families. Genetically engineered mice homozygous for one of the variants are profoundly deaf, whereas heterozygous mice have normal hearing ...
Evan B. Hale +23 more
wiley +1 more source
Mechanical Engineering Journal, 2015 Thermal striping caused by the mixing of fluids at different temperatures is one of the most important issues in the design of Sodium cooled Fast Reactors (SFRs), because it may cause high-cycle thermal fatigue in the structure and affect the structural ...
Masaaki TANAKA, Yasuhiro MIYAKE
doaj +1 more source