Results 211 to 220 of about 10,517,468 (269)

Third Allogeneic Stem Cell Transplantation in Children: A Multicenter Analysis From the Spanish GETH‐TC Pediatric Group

open access: yesEuropean Journal of Haematology, Volume 117, Issue 4, Page 943-952, October 2026.
ABSTRACT Third allogeneic hematopoietic stem cell transplantation (HSCT3) is rarely performed in pediatric patients and is associated with high toxicity and mortality. Data on outcomes in this setting remain scarce. We conducted a retrospective multicenter study within the Spanish GETH‐TC Pediatric group including 29 children and adolescents who ...
Luisa Sisinni   +17 more
wiley   +1 more source

Clonal Hematopoiesis and CAR T Cell Therapy: From Biological Crosstalk to Clinical Implications

open access: yesInternational Journal of Laboratory Hematology, Volume 48, Issue 5, Page 961-971, October 2026.
ABSTRACT Clonal hematopoiesis (CH) is increasingly recognized as a significant biological phenomenon in aging and cancer, marked by the expansion of hematopoietic stem and progenitor cells harboring somatic mutations in genes associated with myeloid neoplasms.
Wei Du   +4 more
wiley   +1 more source

Eosinophilia in the Tropics: Should Empirical Anthelmintic Treatment Be Considered Standard Practice? A Prospective Cohort Study

open access: yesTropical Medicine &International Health, Volume 31, Issue 10, Page 1433-1442, October 2026.
ABSTRACT Background Eosinophilia is a common clinical finding with diverse etiologies. Helminthiasis is a major aetiology in tropical regions, but data from haematology consultation services at tertiary centres in endemic settings are limited. Objectives To determine the prevalence of helminthiasis among patients with eosinophilia at a tropical ...
Smith Kungwankiattichai   +3 more
wiley   +1 more source

Generation of Allogeneic CAR‐T Circumvents Functional Deficits in Patient‐Derived Autologous Product for Glioblastoma

open access: yesInternational Journal of Cancer, Volume 159, Issue 6, Page 1521-1534, 15 September 2026.
Clinical trials of chimeric antigen receptor T‐cell (CAR‐T) therapies in glioblastoma have shown limited clinical benefits. Whether this may be explained by the basal quality of CAR‐T products, which are currently generated using patient, autologous T‐cells, has been little explored.
Sabra K. Salim   +22 more
wiley   +1 more source

T-Lymphoblastic Lymphoma Cells Express High Levels of BCL2, S1P1, and ICAM1, Leading to a Blockade of Tumor Cell Intravasation. [PDF]

open access: yesCancer Cell
Feng H   +15 more
europepmc   +1 more source

Environmental Pesticide Exposure in the Etiology of Pediatric Brain Tumors and Leukemia: A Scoping Review of Epidemiological Studies

open access: yesInternational Journal of Cancer, Volume 159, Issue 6, Page 1360-1384, 15 September 2026.
ABSTRACT Pediatric cancer is a significant cause of morbidity and mortality in children. The etiologies of pediatric cancer are largely unknown, but environmental pesticide exposures are likely to contribute. Chronic low‐dose exposure to pesticide mixtures through drinking water is a growing concern in agricultural communities.
Grace N. VanDeSteeg   +4 more
wiley   +1 more source

Superantigens in Cancer Immunotherapy: Mechanisms, Engineering Strategies, and Therapeutic Potential

open access: yesThe FASEB Journal, Volume 40, Issue 17, 15 September 2026.
Schematic overview of superantigen‐mediated antitumor immune responses and immune suppression within the tumor microenvironment. (1) Antigen‐presenting cells activate T cells through MHC‐II/TCR interactions resulting in the production of cytokines (2) The pro‐inflammatory cytokines released by activated immune cells stimulate downstream immune ...
Urooj Yousaf Virk   +5 more
wiley   +1 more source

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