Results 171 to 180 of about 10,492,376 (301)

Changes in peripheral T-lymphocyte subsets and serum cytokines in patients with systemic sclerosis. [PDF]

Front Pharmacol, 2022
Guo RH, Cheng H, Zhang XY, Yu Z, Wang GH, Hao SY, Gao XP, Wen HY.   +7 more
europepmc   +1 more source

Rhoifolin Alleviates Ulcerative Colitis by Targeting NMNAT1 and Activating SIRT1‐FOXO1 Signaling to Enhance ILC3s Effector Function

Advanced Science, EarlyView.
Rhoifolin directly targets NMNAT1, thereby activating nicotinamide salvage pathway and promoting intracellular NAD+ biosynthesis. Elevated NAD+ levels enhance SIRT1 activity, leading to FOXO1 deacetylation and nuclear translocation. Nuclear FOXO1 subsequently binds to the IL‐22 promoter, upregulating IL‐22 transcription and potentiating ILC3 effector ...
Hongqiong Yang, Yishu Zhang, Sijia Feng, Xiaoqing Ma, Jiayi Feng, Junwei Wang, Jialin Gao, An Pan, Dapeng Wu, Kang Ding, Caijuan Zheng, Qi Lv, Lihong Hu   +12 more
wiley   +1 more source

Correction: Effects of graded exercise rehabilitation on inflammatory factors and T-lymphocyte subsets in patients with acute exacerbation of chronic obstructive pulmonary disease: a randomized controlled trial. [PDF]

Front Med (Lausanne)
Chen Y, Ran HM, Wang Y, Fu DD, Yang NN, Cheng CL, Liu R, Luo LW, Luo JM, Ma LN, Zeng H.   +10 more
europepmc   +1 more source

Cumulative physiological stress is associated with age-related changes to peripheral T lymphocyte subsets in healthy humans. [PDF]

Immun Ageing, 2023
Snodgrass RG, Jiang X, Stephensen CB, Laugero KD.   +3 more
europepmc   +1 more source

AARS1‐Mediated RUNX3 K193 Lactylation Enhances the Activation and Cytotoxicity of CD8+T Cells in Smoking‐Related Emphysema

Advanced Science, EarlyView.
Exposure to CS causes an elevation of AARS1 levels, which increases the levels of RUNX3 lactylation at the K193 site and increases protein levels of RUNX3 through inhibition of autolysosomal degradation. Elevated RUNX3 levels promote CD8+T cell activation and augment their cytotoxicity, which induces alveolar epithelial cell death and facilitates the ...
Ying Zhu, Jiaheng Lin, Yifan Li, Qiaoqiao Zhou, Min Yu, Cheng Cheng, Kang Chang, Dang Lin, Tao Bian, Yan Wu, Lu Lu, Haibo Xia, Qizhan Liu   +12 more
wiley   +1 more source

Characteristics of T-lymphocyte subsets in patients with severe fever with thrombocytopenia syndrome complicated with invasive pulmonary aspergillosis: a retrospective study. [PDF]

Front Immunol
Xu Y, Liu Y, Qian Y, Liu N, Tang J, Dong D, Xia M, Wu W, Gu Q.   +8 more
europepmc   +1 more source

Effects of theophylline combined with inhaled corticosteroids on patients with moderate and severe asthma and changes of T lymphocyte subsets in peripheral blood. [PDF]

Cent Eur J Immunol, 2023
Cai X, Rong R, Huang Y, Pu X, Ge N.
europepmc   +1 more source

GM‐CSF Promotes Neutrophil PD‐L1 Expression Through the VEGFR‐2/STAT6/CSF2 Signaling Axis in Oral Squamous Cell Carcinoma

Advanced Science, EarlyView.
VEGFR‐2 signaling in OSCC activates Src–STAT6‐dependent CSF2 transcription, driving tumor‐derived GM‐CSF secretion. GM‐CSF programs neutrophils to express PD‐L1 through STAT5–mTOR/S6K signaling, suppressing cytotoxic CD8+ T cells. This pathway reveals a tumor–neutrophil immune checkpoint circuit that limits anti‐PD‐1 responsiveness in OSCC.
Fangxing Zhu, Yuanhe You, Yiyi Zhang, Yibin Dai, Xinyu Zhou, Yong Fu, Xi Lu, Yingying Huang, Zhihang Zhou, Ronghui Xia, Wutong Ju, Zhaoqi Yuan, Laiping Zhong, Tongchao Zhao   +13 more
wiley   +1 more source

T-Lymphocyte Subsets in Apparently Healthy Nigerian Children

International Journal of Pediatrics, 2010
Emmanuel Oni Idigbe, Rosemary A. Audu, Edna O. Iroha, Adebola O. Akinsulie, Edamisan Olusoji Temiye, Veronica C. Ezeaka, Ifedayo M. O. Adetifa, Adesola Z. Musa, Joseph Onyewuche, Sylvester U. Ikondu   +9 more
doaj   +1 more source

Association Between Respiratory Viral Infection and Peripheral T Lymphocyte Subsets in Elderly Patients With Acute Exacerbation of Bronchiectasis. [PDF]

Clin Respir J
Zhang G, Zhuang Y, Wang S, Wang Q, Qin J, Yuan Z, Zheng J.   +6 more
europepmc   +1 more source