Results 191 to 200 of about 172,749 (310)

Reprogramming Antitumor Immunity: NK Cell Strategies to Navigate the Immunosuppressive Tumor Microenvironment

Advanced Science, EarlyView.
ABSTRACT Tumor immune escape is a major barrier to durable cancer immunotherapy, as advanced malignancies create a tumor microenvironment (TME) that preferentially exhausts and disables T cell responses. While most approved cell therapies are T cell‐based, this limitation motivates the exploration of an alternative effector cell platform.
Tereza Kochs, Pranay Nath, Alice Chen, Rizwan Romee, Andreia Maia   +4 more
wiley   +1 more source

Changes in T-lymphocyte subsets and natural killer cells of patients after out-of-hospital cardiac arrest and resuscitation: a retrospective study. [PDF]

Resusc Plus
Shan Z, Hang C, Wang X, Shao R, An L, Tang Z.   +5 more
europepmc   +1 more source

Rare Case of Persistently Depressed T Lymphocyte Subsets After SARS-CoV-2 Infection. [PDF]

Am J Case Rep, 2022
Alebna PL, Bellamy S, Tabur TA, Mangia A.   +3 more
europepmc   +1 more source

Integrated Single‐Cell and Spatial Analysis Reveals a Metabolic‐Immune Axis Driving Aortic Dissection

Advanced Science, EarlyView.
Single‐cell and spatial profiling of 110 human thoracic aortic samples reveals a stromal–immune circuit driving aortic dissection. An elastin‐rich fibroblast subset is depleted with age and markedly reduced in disease, weakening aortic wall integrity.
Jing Tao, Huanjie Yang, Jiahui Yong, Xueting Chen, Qiang Zhao, Xueli Wu, Lei Yan, Li Pang, Fan Luo, Mengjun Yu, Shanshan Pan, Deyang Li, Rouxi Chen, Juan Wang, Zhensheng Dong, Fan Yang, Yue Wang, Yang Chen, Hongjian Zheng, Zhimin Yang, Zijie Wang, Karsten Kristiansen, Hui Peng, Xiaodong Fang, Juan Shen, Yining Yang   +25 more
wiley   +1 more source

Response to letter regarding "Peripheral and intestinal T lymphocyte subsets in dogs with chronic inflammatory enteropathy". [PDF]

J Vet Intern Med
García-Sancho M, Agulla B, Villaescusa A, Sainz Á, Díaz-Regañón D, Rodríguez-Franco F, Calleja-Bueno L, Olmeda P.   +7 more
europepmc   +1 more source

Peripheral blood T-lymphocyte subsets are potential biomarkers of disease severity and clinical outcomes in patients with ulcerative colitis: a retrospective study. [PDF]

BMC Gastroenterol, 2023
Geng B, Ding X, Li X, Liu H, Zhao W, Gong H, Tian Z, Guo J.   +7 more
europepmc   +1 more source

Decoding Undesirable Inflammatory Responses of Nucleic Acid‐Delivering Lipid Nanoparticles

Advanced Science, EarlyView.
Lipid nanoparticles (LNPs) enable efficient nucleic acid delivery, but their immunogenicity is a double‐edged sword. This review explores LNP‐driven innate and adaptive immunity, covering lipid components, endosomal escape, and nucleic acid sensing.
Ruimin Hu, Yin Dou, Chenwen Li, Yuying Mu, Huiying Ouyang, Wenhao Shen, Jianxiang Zhang   +6 more
wiley   +1 more source

T-Lymphocyte Subsets in Apparently Healthy Nigerian Children

International Journal of Pediatrics, 2010
Emmanuel Oni Idigbe, Rosemary A. Audu, Edna O. Iroha, Adebola O. Akinsulie, Edamisan Olusoji Temiye, Veronica C. Ezeaka, Ifedayo M. O. Adetifa, Adesola Z. Musa, Joseph Onyewuche, Sylvester U. Ikondu   +9 more
doaj   +1 more source

Differences and clinical significance of liver - kidney function parameters, inflammatory markers and peripheral blood T lymphocyte subsets in patients with HBV - related acute - on - chronic liver failure. [PDF]

BMC Gastroenterol
Dou Y, Zhang L, Wang H.
europepmc   +1 more source

Lighting up Macrophage Reprogramming Assists Immunosuppressive Niche Modulation in Primary Tumors and Tumor‐Draining Lymph Nodes of Breast Cancer

Advanced Science, EarlyView.
This study develops an intelligent NIR‐II‐responsive nanoplatform to combat immunosuppression in breast cancer. It enables real‐time visualization of macrophage activity via “off‐on” fluorescence while simultaneously reprogramming macrophages through the CSF‐1R and CD47‐SIRPα pathways.
Yingbo Li, Di Chang, Jie Yang, Ying Bai, Min Chen, Daoshuang Li, Zuoyu Xu, Jiaxin Yuan, Xiaoxuan Xu, Zhiqi Zhang, Yize Li, Zixin Chen, Jinbing Xie, Zebin Xiao, Shenghong Ju   +14 more
wiley   +1 more source