Results 201 to 210 of about 132,916 (265)

Establishment and characterization of mouse lymph node fibrosis models

open access: yesAnimal Models and Experimental Medicine, EarlyView.
The design of the entire paper. Schematic illustration of four strategies for establishing mouse lymph node (LN) fibrosis models. The study further compares their fibrotic remodeling patterns and immune alterations. Abstract Background Lymph node (LN) fibrosis occurs in a variety of pathological conditions, including HIV infection, obesity, cancer, and
Yaru Niu   +8 more
wiley   +1 more source

From Marginal to Central: Marginal Zone‐like B Cells as Critical Targets in Cladribine‐Treated Multiple Sclerosis

open access: yesAnnals of Neurology, EarlyView.
Objective Multiple sclerosis (MS) is a chronic autoimmune disease where B cells play a central pathogenic role. Cladribine, an oral therapy, provides durable benefits by reshaping lymphocyte populations, yet its specific long‐term impact on distinct B‐cell subsets is not fully understood.
Marta Pirronello   +20 more
wiley   +1 more source
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T Lymphocyte Subsets in Uveitis

American Journal of Ophthalmology, 1983
We evaluated the peripheral T-cell subsets in 32 adult patients with intraocular inflammatory disease and 12 age-matched normal controls by means of the OKT series of monoclonal antibodies in conjunction with the laser cytofluorograph, which quantitatively determines the fluorescence intensity of lymphocytes.
R B, Nussenblatt   +3 more
openaire   +2 more sources

T‐Lymphocyte Subsets in Leprosy

International Journal of Dermatology, 1983
ABSTRACT:Immunologic abnormalities in T cells have been reported in patients with lepromatous leprosy. Ten patients with leprosy (eight lepromatous, one dimorphous, one tuber‐culoid) were studied in order to detect the proportions of total T lymphocytes and helper as well as suppressor subsets, using monoclonal antibodies in an indirect ...
R, Gonzalez-Amaro   +3 more
openaire   +2 more sources

T-lymphocyte subsets in acute illness

Critical Care Medicine, 1995
To determine the range of T-lymphocyte subsets (CD4, CD8, and CD4/CD8 ratios) in acutely ill, hospitalized patients and to determine whether these concentrations correlate with illness severity, survival rate, or immunodepression.Cross-sectional study, comparing Acute Physiology and Chronic Health Evaluation II (APACHE II) scores and the calculated ...
C, Feeney   +5 more
openaire   +2 more sources

T‐lymphocyte subset distribution in human spleen

European Journal of Clinical Investigation, 2006
AbstractBackground  When analyzing human cellular immune responses, most focus is placed on the peripheral blood (PB) and, to a lesser extent, the lymph nodes. To date the spleen has not been analyzed with regard to its role in adaptive cellular immunity and more notably not with respect to T‐cell immune responses.Materials and methods  We analyzed the
Langeveld, M.   +2 more
openaire   +3 more sources

Modeling the lifespan of human T lymphocyte subsets

Mathematical Biosciences, 1997
T lymphocytes may be classified as naive or memory cells, depending on whether they possess immunological memory. The central tenet of this work is that memory lymphocytes revert to naive lymphocytes in vivo. This phenomenon is modeled by a mechanism qualitatively similar to Demoivre's law of human mortality.
Hurn, A. S.   +2 more
openaire   +2 more sources

PERIPHERAL T LYMPHOCYTES AND THEIR SUBSETS IN CUTANEOUS TUBERCULOSIS

International Journal of Dermatology, 1992
AbstractFifty‐four patients with cutaneous tuberculosis, consisting of 23 with lupus vulgaris,22 with scrofuloderma, and nine with verrucosa cutis, were investigated for cell‐mediated immunity, through estimation of peripheral total T lymphocytes (CD3+), CD4+ (helper/inducer), and CD8+ (cytotoxic/suppressor) lymphocytes, by immunohistochemical staining
V N, Sehgal   +3 more
openaire   +2 more sources

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