Results 221 to 230 of about 132,916 (265)
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Differential Regulation of Murine T Lymphocyte Subsets
Annual Review of Immunology, 1993Signaling pathways in T lymphocytes have been incompletely characterized. It is evident that differences exist among the T cell subsets. We have defined several distinct mechanisms that affect differentially the activities of murine T lymphocyte clones representing various CD4+ and CD8+ subsets: Interferon-gamma (IFN-gamma) inhibits proliferation of ...
F W, Fitch +3 more
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T-lymphocyte Subsets in Occupationally Exposed Persons
International Journal of Radiation Biology, 1990The percentage of CD2+, CD4+, CD8+ and HNK-1+ cells in peripheral blood was investigated in persons occupationally exposed to very low doses of ionizing radiation. Investigations were carried out by monoclonal antibodies and flow cytometry. While significant effects of age and smoking habits on the relative number of CD8 cells and CD4/CD8 ratios could ...
H, Tuschl, R, Kovac, A, Wottawa
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T lymphocyte subsets in Mediterranean spotted fever
Acta tropica, 1988Several studies have previously suggested the possible role of a T lymphocyte suppressor population in infections by species of the genus Rickettsia. In 15 patients with Mediterranean spotted fever (MSF), we quantified, during the acute and convalescent phases of the disease, the peripheral blood lymphocyte populations using monoclonal antibodies that ...
Herrero Herrero, José Ignacio +2 more
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T Lymphocytes Subsets in Experimental Iron Overload
Immunopharmacology and Immunotoxicology, 1997Several abnormalities of the immune system have been reported in association with clinical and experimental iron overload. To dissect further such abnormalities, changes in lymphocyte subsets were evaluated in iron-loaded male Sprague-Dawley rats. The iron-loading protocol consisted of a total dose of irondextran (1.5 mg/Kg body weight) divided in ...
J E, Cardier, E, Romano, A, Soyano
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Regulation of T lymphocyte subsets.
Ciba Foundation symposium, 1996Patterns of cytokine secretion and functional differences distinguish T lymphocyte subsets. T lymphocyte subsets are also regulated differentially. Most established CD8+ lymphocyte clones secrete gamma-interferon (IFN-gamma) but not interleukin 2 (IL-2) or IL-4.
F W, Fitch +4 more
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T-lymphocyte subsets in idiopathic dilated cardiomyopathy
The American Journal of Cardiology, 1985Idiopathic dilated cardiomyopathy (IDC) is a common clinical problem in Africa. To determine if there is a defect of immune regulation in patients with IDC, the percentage of total T-cells (OKT3 positive), helper/inducer cells (OKT4 positive) and suppressor/cytotoxic cells (OKT8 positive) were measured using monoclonal antibodies in 20 patients with ...
Sanderson, JE +3 more
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Renewal rates of murine T-lymphocyte subsets
Cellular Immunology, 1990The proliferative dynamics of T-cell subsets in lymphoid organs of BALB/c mice have been evaluated by means of [3H]thymidine injections for up to 3 days, followed by FACS and autoradiography. In the thymus, cells positive for both CD4 and CD8 antigens were more rapidly renewed than single-positive cells.
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Abnormal T-Lymphocyte Subsets in Type I Diabetes
Diabetes, 1989Type I (insulin-dependent) diabetes mellitus is a slow autoimmune disease associated with the selective destruction of β-cells in the islets of Langerhans. Recent studies in humans indicate that autoantibodies to insulin and islets of Langerhans appear years before overt diabetes and identify a normoglycemic prediabetic state. To determine whether type
D, Faustman +3 more
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T-lymphocyte subsets in primary and secondary glomerulonephritis.
Proceedings of the European Dialysis and Transplant Association. European Dialysis and Transplant Association, 1983T-lymphocyte subsets, using the monoclonal antibodies OKT3 (peripheral T-cells), OKT4 (helper/inducer T-cells) and OKT8 (suppressor/cytotoxic T-cells) were measured in peripheral blood from 110 patients with various forms of primary and secondary glomerulonephritis (GN) (Berger's disease, membranous GN, focal glomerulosclerosis, membranoproliferative ...
Fornasieri, A +7 more
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Variations in T Lymphocyte Subsets in IgA Nephropathy
1989Berger’s disease is an IgA nephropathy characterized by irregular hematuria and variable proteinuria (1). Generally considered as benign, it may neverthless progress towards chronic renal failure (2). Though its pathogenesis is unknown, IgA serum levels are important. This immunoglobulin acts on the mucosal surface protecting towards the antigens.
SANNA M +7 more
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