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T Lymphocyte Subsets in Uveitis
American Journal of Ophthalmology, 1983We evaluated the peripheral T-cell subsets in 32 adult patients with intraocular inflammatory disease and 12 age-matched normal controls by means of the OKT series of monoclonal antibodies in conjunction with the laser cytofluorograph, which quantitatively determines the fluorescence intensity of lymphocytes.
R B, Nussenblatt +3 more
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T‐Lymphocyte Subsets in Leprosy
International Journal of Dermatology, 1983ABSTRACT:Immunologic abnormalities in T cells have been reported in patients with lepromatous leprosy. Ten patients with leprosy (eight lepromatous, one dimorphous, one tuber‐culoid) were studied in order to detect the proportions of total T lymphocytes and helper as well as suppressor subsets, using monoclonal antibodies in an indirect ...
R, Gonzalez-Amaro +3 more
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T-lymphocyte subsets in acute illness
Critical Care Medicine, 1995To determine the range of T-lymphocyte subsets (CD4, CD8, and CD4/CD8 ratios) in acutely ill, hospitalized patients and to determine whether these concentrations correlate with illness severity, survival rate, or immunodepression.Cross-sectional study, comparing Acute Physiology and Chronic Health Evaluation II (APACHE II) scores and the calculated ...
C, Feeney +5 more
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T‐lymphocyte subset distribution in human spleen
European Journal of Clinical Investigation, 2006AbstractBackground When analyzing human cellular immune responses, most focus is placed on the peripheral blood (PB) and, to a lesser extent, the lymph nodes. To date the spleen has not been analyzed with regard to its role in adaptive cellular immunity and more notably not with respect to T‐cell immune responses.Materials and methods We analyzed the
Langeveld, M. +2 more
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Modeling the lifespan of human T lymphocyte subsets
Mathematical Biosciences, 1997T lymphocytes may be classified as naive or memory cells, depending on whether they possess immunological memory. The central tenet of this work is that memory lymphocytes revert to naive lymphocytes in vivo. This phenomenon is modeled by a mechanism qualitatively similar to Demoivre's law of human mortality.
Hurn, A. S. +2 more
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PERIPHERAL T LYMPHOCYTES AND THEIR SUBSETS IN CUTANEOUS TUBERCULOSIS
International Journal of Dermatology, 1992AbstractFifty‐four patients with cutaneous tuberculosis, consisting of 23 with lupus vulgaris,22 with scrofuloderma, and nine with verrucosa cutis, were investigated for cell‐mediated immunity, through estimation of peripheral total T lymphocytes (CD3+), CD4+ (helper/inducer), and CD8+ (cytotoxic/suppressor) lymphocytes, by immunohistochemical staining
V N, Sehgal +3 more
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T-Lymphocyte Subsets in Adult Coeliac Disease
Clinical Science, 19831. As a defect of suppressor function has been hypothesized in the pathogenesis of coeliac disease, we measured, by monoclonal antibodies, the inducer/suppressor T-cell ratio in adult coeliac disease. 2. No statistical difference was observed between coeliac patients and healthy controls, irrespective of treatment and HLA status.
G R, Corazza +5 more
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Demonstration in situ of subsets of T-lymphocytes in sarcoidosis
The American Journal of Dermatopathology, 1984Five biopsy specimens of skin, four of lung, and one of a lymph node were taken from nine patients with sarcoidosis. Monoclonal antibodies were applied to frozen sections of the specimens by an immunoperoxidase technique to test for the presence and distribution of subsets of T-lymphocytes.
R L, Modlin +5 more
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T‐lymphocyte subsets in the human lacrimal gland
Acta Ophthalmologica, 1988Abstract. This study examines the microscopical appearance, location, distribution, subdivision and density of T‐lymphocytes in the human lacrimal gland. Fourteen glands, 7 from either sex, were removed and frozen shortly after the donors' death, and processed for immunoperoxidase staining, utilizing a biotinavidin system and one of the following ...
O G, Gudmundsson +2 more
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