Results 71 to 80 of about 172,749 (310)

Two-Color Immunofluorescene and Flow Cytometric Analysis of Peripheral Blood Lymphocyte Subsets in Aging Humans [PDF]

, 1992
Using two-color immunofluorescence, multiparameter flow cytometry has been used to examine the antigenic characteristics of the nature of changes due to aging in lymphocyte subests.
Itsuno, Minoru, Senju, Masahiro, Oda, Hidetosi, Omagari, Katsuhisa, Makiyama, Kazuya, Nakamuta, Koji, Hara, Kohei   +6 more
core  

Measuring lymphocyte kinetics in tropical field settings.

, 2005
Studies involving in-vivo labelling of lymphocyte DNA with 6,6-2H2-glucose to track T-cell turnover have contributed to understanding lymphocyte homeostasis in health and disease.
Griffin, George E, Wallace, Diana L, Ghattas, Hala, Macallan, Derek C, Darboe, Bakary M, Prentice, Andrew M   +5 more
core   +1 more source

Relationship between T-lymphocyte Subsets and Suppressor Cell Activity in Patients with Chronic Active Hepatitis B [PDF]

, 1989
Thirty-nine patients with chronic HBV infection and 38 normal persons were investigated by simultaneous assay of T suppressor cell function and enumeration of T-lymphocyte subsets by monoclonal antibodies. In patients with chronic active hepatitis B (CAH-
Jang, Tae Won, Park, Byung Chae, Koo, Ja Young   +2 more
core   +1 more source

Infusible Extracellular Matrix Biomaterial Enhances Cell‐Specific Pro‐Repair Responses Following Acute Myocardial Infarction

Advanced Healthcare Materials, EarlyView.
We measure the cell‐specific responses of administering infusible ECM (iECM) in acute myocardial infarction (MI) across multiple timepoints. Using single‐nucleus RNA sequencing and spatial transcriptomics, we measure macrophage activation, fibroblast remodeling, increased vascular development, lymphangiogenesis, cardioprotection, and neurogenesis ...
Joshua M. Mesfin, Alexander Chen, Quincy P. Lyons, Michael B. Nguyen, Maria L. Karkanitsa, Justin Yu, Van K. Ninh, Emily Gardner, Elyse G. Wong, Sriya N. Paleti, Julian Cheng, Benjamin D. Bridgelal, Kate E. Reimold, Selena Cao, Connor Uhre, Colin G. Luo, Zhenxing Fu, Kevin R. King, Karen L. Christman   +18 more
wiley   +1 more source

Persistent attenuation of lymphocyte subsets after mass SARS-CoV-2 infection

International Journal of Infectious Diseases
Objectives: Growing evidence suggests that lymphocyte subsets are declined in COVID-19 patients, but it is unclear if these alterations persist after widespread exposure to SARS-CoV-2 or how long they last.
Zhengqi Jiang, Tichao Shan, Yucan Li, Fengjiao Han, Baobao Feng, Xiaohui Zhen, Ji Ma, Heyu Ni, Jun Peng, Miao Xu   +9 more
doaj   +1 more source

Enhanced Human Antigen‐Specific B Cell Responses Using In Vitro 3D Tonsil Cultures Containing Stromal Cells

Advanced Healthcare Materials, EarlyView.
We developed a fully human 3D tonsil cell culture system incorporating supportive stromal cells that better sustains and activates immune cells than conventional methods. The model generates stronger, more targeted antibody responses to viral antigens and vaccines, providing a physiologically relevant and entirely human platform for studying immune ...
Maaike V. J. Braham, Marlon de Gast, Liubov Babii, Sabine Kruijer, Theo M. Bestebroer, Mathilde Richard, Mathieu Claireaux, S. Marieke van Ham, Jelle de Wit, Cécile A. C. M. van Els, Anja ten Brinke, Marit J. van Gils   +11 more
wiley   +1 more source

Peripheral Blood Lymphocyte Subsets and Clinical Parameters in Patients Undergoing Renal Biopsy

Kidney Diseases
Introduction Chronic kidney disease (CKD) is a major global health burden characterized by immune dysregulation. Peripheral blood lymphocyte subsets can reflect immune status across CKD pathologies. We evaluated associations between lymphocyte
Xingyang Zhao, Meng Wang, Sujia Hu, Dan Yang, Yichun Cheng, Shuwang Ge, Gang Xu   +6 more
doaj   +1 more source

Human memory CD8+ T-cells exhibit an intrinsic metabolic advantage as reflected by increased mitochondrial functionality and high glycolytic potential [PDF]

, 2013
Intrinsic differences between na•ve and memory CD8+ T-cells affect both quality and quantity of cognate antigen response. Cellular immune function and metabolic pathways are closely linked.
Gubser, Patrick Marc
core   +1 more source

One‐Step Microfluidic Manufactured Fucose‐Decorated Sweetosomes Choose the Time and the Road for Their Intracellular Journey to Cancer Treatment

Advanced Healthcare Materials, EarlyView.
Sweetosomes, a new class of fucose‐decorated liposomes, are developed via a one‐step microfluidic process without surface chemistry. This study elucidates their main caveolae‐mediated entry and distinct endosomal trafficking. These nanostructures demonstrate superior endosomal escape, organelle acidity modulation, and prolonged plasma persistence ...
Mattia Tiboni, Mariele Montanari, Shiva Khorshid, Michele Verboni, Andrea Duranti, Simone Lucarini, Daniele Lopez, Annalisa Aluigi, Gianluca Morganti, Michele Menotta, Giovanna Panza, Daniel J. Klionsky, Barbara Canonico, Luca Casettari   +13 more
wiley   +1 more source

Age-related impairment of human T lymphocytes' activation: specific differences between CD4+ and CD8+ subsets

, 2006
The relevance of physiological immune aging is of great interest with respect to determining disorders with pathologic immune function in aging individuals.
Maurer, Konrad, Schindowski, Katharina, Frölich, Lutz, Eckert, Anne, Müller, Walter E.   +4 more
core