Results 241 to 250 of about 162,976 (285)

Selective Tropism of Lymphadenopathy Associated Virus (LAV) for Helper-Inducer T Lymphocytes

Science, 1984
Lymphadenopathy associated virus (LAV) has been isolated from patients with the acquired immunodeficiency syndrome (AIDS) or lymphadenopathy syndrome. Since the immune deficiency in AIDS seems to be primarily related to the defect of the helper-inducer T lymphocyte subset, the possibility that LAV is selectively tropic for this subset was investigated.
David Klatzmann, Francoise Barré-Sinoussi, Marie Thèrése Nugeyre, Claude Danguet, Etienne Vilmer, Claude Griscelli, Francoise Brun-Veziret, Christine Rouzioux, Jean Claude Gluckman, Jean-Claude Chermann, Luc Montagnier   +10 more
openaire   +4 more sources

The preferential accumulation of helper‐inducer T lymphocytes in inflammatory lesions: evidence for regulation by selective endothelial and homotypic adhesion

European Journal of Immunology, 1988
AbstractThe mechanisms which lead to the accumulation of T lymphocytes into inflammatory lesions are not clearly understood. We have previously shown that synovial CD4 T lymphocytes are mostly CDw29UCHL1 (helper‐inducer cells) and very few carry the CD45R antigen which identifies the suppressor‐inducer subset.
Costantino Pitzalis, Gabrielle H. Kingsley, Gabriel S. Panayi, Dorian O. Haskard   +3 more
openaire   +4 more sources

Helper-Inducer and Suppressor-Inducer Lymphocyte Subsets in Alcoholic Cirrhosis

Scandinavian Journal of Gastroenterology, 1991
Peripheral blood lymphocytes from patients with alcoholic cirrhosis, alcohol-induced fatty liver, and healthy controls were analyzed for helper-inducer (CD4+CD29w+) and suppressor-inducer (CD4+CD45R+) T lymphocytes. In confirmation of earlier reports, patients with alcoholic cirrhosis were found to have a significantly reduced absolute number of ...
J. Göttlicher, M. M. Eibl, H. M. Wolf, Ch. Müller   +3 more
openaire   +4 more sources

Antigenic polymorphism of the T4 differentiation antigen expressed on human T helper/inducer lymphocytes

Human Immunology, 1984
The human TH lymphocyte population has been established to express a differentiation antigen (T4) which appears to function in cellular collaboration and T cell recognition of Class II MHC alloantigens. Because we observed altered immunofluorescence staining of the TH cells of some individuals using the OKT4 mAb, a systematic investigation on both the ...
Robert B. Colvin, Anne A. Fuller, Patrick C. Kung, Jane E. Trevithick, A. Benedict Cosimi, Thomas C. Fuller   +5 more
openaire   +4 more sources

Displacement of T Lymphocytes with the ‘Helper/Inducer’ Phenotype from Peripheral Blood to Lymphoid Organs in Untreated Patients with Hodgkin's Disease

Scandinavian Journal of Haematology, 1983
A panel of previously characterized monoclonal antibodies: B67.6, OKT3, OKT4, B53.4, Leu3a, OKT8, Leu2a, OKM1, M12 and B52.1 were used as a probe to assess mononuclear cells in peripheral blood (PB), lymph nodes (LN) and spleens of untreated patients with Hodgkin's disease (HD).
ROMAGNANI, SERGIO, DEL PRETE, GIANFRANCO, MAGGI, ENRICO, BOSI, ALBERTO, F. Bernardi, P. Ponticelli, S. Di Lollo, M. Ricci   +7 more
openaire   +5 more sources

T-cell inducer populations in cutaneous inflammation: a predominance of T helper-inducer lymphocytes (THi) in the infiltrate of inflammatory dermatoses

British Journal of Dermatology, 1990
The mononuclear infiltrate found in a variety of inflammatory dermatoses was characterized by a predominance of T helper-inducer lymphocytes (THi), CD4+/CD45RA-/CD45RO+, a population of cells responsible for maintaining and promoting immune reactions. Only small numbers of T-suppressor-inducer lymphocytes (TSi), CD4+/CD45RA+/CD45RO-, cells responsible ...
Donald M. MacDonald, Michael H. Allen, A.C. Markey, Costantino Pitzalis   +3 more
openaire   +4 more sources

Abnormal Function of CD4+ Helper/Inducer T Lymphocytes in a Patient With Widespread Human Papillomavirus Type 3-Related Infection

Archives of Dermatology, 1990
Human papillomavirus-induced infections may be associated with cellular immunodeficiency. However, very little is known about the dysfunctional interactions among T lymphocytes, B lymphocytes, and antigen-presenting cells. A 30-year-old heterosexual man with a 10-year history of persistent multiple refractory flat wart lesions containing human ...
Gunhild L. Vejlsgaard, Erik R. Hansen, Ole Baadsgaard, Vincent C. Ho, E.-M. de Villiers, Steen Lisby   +5 more
openaire   +4 more sources

Monoclonal Antibodies to T-helper/Inducer and T-suppressor/Cytotoxic Lymphocyte Subsets Recognize Antigens on Splenic Sinusoidal Lining Cells

American Journal of Clinical Pathology, 1984
Most of the monoclonal antibodies (MoAbs) to T-lymphocyte subsets are, with few exceptions thought to recognize antigens (Ags) unique to T-cells. The authors examined the distribution of cells reacting with MoAbs to the helper/inducer (OKT4, anti-Leu-3a,b) and suppressor/cytotoxic (OKT8, anti-Leu-2a) T-lymphocyte subsets and to "pan T" Ags (anti-Leu-1,
Susan A. Dickson, Patrick J. Buckley
openaire   +4 more sources

Phenotypic analysis of lamina propria lymphocytes. Predominance of helper-inducer and cytolytic T-cell phenotypes and deficiency of suppressor-inducer phenotypes in Crohn's disease and control patients.

Gastroenterology, 1986
To better define the nature of intestinal T cells, the phenotypes of isolated lamina propria lymphocytes (LPL) were determined in both Crohn's disease patients and control patients using combinations of monoclonal antibodies that have been found to correlate with particular immunoregulatory functions.
S P, James, C, Fiocchi, A S, Graeff, W, Strober   +3 more
openaire   +3 more sources

Chemoattractant lymphokines specific for the helper/inducer T-lymphocyte subset

Cellular Immunology, 1985
The cellular content of T-lymphocyte-rich inflammatory sites is dependent in part on the in situ elaboration of chemoattractant factors. We have previously described three T-lymphocyte-specific chemoattractant lymphokines; a chemokinetic factor, lymphocyte chemoattractant factor (LCF, MW 56,000), and two distinct lymphocyte migration inhibitory factors
J S, Berman, W W, Cruikshank, D M, Center, A C, Theodore, D J, Beer   +4 more
openaire   +3 more sources