Results 251 to 260 of about 162,976 (285)

Unusual Lack of the Epitope Recognized by OKT4 on the Helper/Inducer T Lymphocytes

Pediatrics International, 1985
AbstractLack of the epitope recognized by OKT4 monoclonal antibody on the helper/inducer T lymphocytes in a 14‐year‐old boy with IgA nephritis is described.The lymphocytes reacted normally with OKT3 /Leu4 and OKT8/αLeu2a monoclonal antibodies but not with OKT4 monoclonal antibody.
Yuichi Ogura, Osamu Jinbo, Mutsumi Murakami, Yoshitaka Fukunaga, Robert A. Good, Masao Yamamoto, Yutaka Ueda   +6 more
openaire   +2 more sources

Abnormal distribution of the helper-inducer and suppressor-inducer T-lymphocyte subsets in the rheumatoid joint

Clinical Immunology and Immunopathology, 1987
T lymphocytes can be divided into two main phenotypic populations, CD4 and CD8. These can be further subdivided into 2H4, 4B4, or UCHL1 subsets by appropriate monoclonal antibodies. We have investigated these subsets in the synovial fluid of patients with rheumatoid arthritis and have found (i) a virtual absence of CD4+ 2H4+ and the marked reduction of
Gabriel S. Panayi, Gabrielle H. Kingsley, John R. Murphy, Costantino Pitzalis   +3 more
openaire   +3 more sources

Predominance of T cells that express CD45R in the CD4+ helper/inducer lymphocyte subset of neonates

Clinical Immunology and Immunopathology, 1989
Neonates have an increased risk of severe infections. For several in vitro and in vivo immune responses, neonates have been shown to have significant differences when compared to normal adults. To indirectly study immune cellular defects, we compared cell surface markers on cord blood lymphocytes (CBL) from 58 term infants to peripheral blood ...
Stanley M. Shiigi, Donna L. Ching, John S. Bradley, Linda M. Bradley   +3 more
openaire   +3 more sources

Cyclosporin a inhibits helper/inducer surface antigen expression on activated human lymphocytes

International Journal of Immunopharmacology, 1985
Helper/inducer (H/I) and cytotoxic/suppressor (C/S) subpopulations of human peripheral blood mononuclear lymphocytes (PBL) were cultured with Concanavalin A (Con A) and Cyclosporin A (CsA) to determine effects on proliferation and surface marker expression.
Jon R. Schmidtke, Philip Marder
openaire   +3 more sources

[Effects of surgical operation on helper-inducer T-lymphocytes in sino-nasal neoplasms patients].

Zhonghua yi xue za zhi, 2013
To explore the effects of surgical operation on helper-inducer T-lymphocytes (Th1/Th2) in sino-nasal neoplasms.From January 2004 to December 2011, 80 patients with malignant tumor in nasal cavities or sinuses were enrolled as experimental group and another 80 subjects with deflection of nasal septum as control group. The phorbol-12-myristate-13-acetate
Yong Yuan, Qin-song Liu, Jing-hua Li, Wei-guo Xue, Jie Sun   +4 more
openaire   +3 more sources

1,25-Dihydroxyvitamin D3 suppresses human T helper/inducer lymphocyte activity in vitro.

The Journal of Immunology, 1985
Abstract The active form of vitamin D3, 1 alpha,25-dihydroxyvitamin D3 (1,25-(OH)2-D3), suppresses in vitro immunoglobulin (Ig) production by activated peripheral blood mononuclear cells (PBM) from normal human subjects by inhibiting T helper/inducer TH cell activity. Normal PBM were fractionated into B, TH and T suppressor/cytotoxic (Ts)
J M, Lemire, J S, Adams, V, Kermani-Arab, A C, Bakke, R, Sakai, S C, Jordan   +5 more
openaire   +2 more sources

Effects of job strain on helper-inducer (CD4+CD29+) and suppressor-inducer (CD4+CD45RA+) T cells in Japanese blue-collar workers.

Psychotherapy and Psychosomatics, 1997
BACKGROUND The effects of job strain on helper-inducer (CD4+CD29+) T cells and suppressor-inducer (CD4+CD45RA+) T cells are not clear. METHODS The subjects were 65 male blue-collar workers in a chemical plant in Japan.
N. Kawakami, T. Tanigawa, S. Araki, A. Nakata, S. Sakurai, K. Yokoyama, Y. Morita   +6 more
semanticscholar   +1 more source

T‐cell chronic lymphocytic leukemia with a helper/inducer membrane phenotype: A distinct clinicopathologic subtype with a poor prognosis

American Journal of Hematology, 1986
AbstractT‐cell chronic lymphocytic leukemia (T‐CLL) accounts for about 2% of the various types of CLL and can be subtyped into helper/inducer (h/i) and cytotoxic/suppressor (c/s) cell membrane phenotypes. Seven patients with CLL were shown to have T‐CLL with a h/i cell membrane phenotype; four with monoclonal antibody reagents and three by ...
Gordon W. Dewald, Robert L. Phyliky, Chin-Yang Li, Henry A. Homburger, Thomas E. Witzig, Barry S. Handwerger   +5 more
openaire   +3 more sources

Expression of c-myc in Stimulated T Lymphocytes of the Helper/Inducer Phenotype Producing Lymphokine(s) Supporting Multilineage Colony Formation

Acta Haematologica, 1986
Phytohemagglutinin (PHA) renders human peripheral T lymphocytes competent to replicate their DNA and divide. The stimulation of peripheral T cells of the T4 phenotype by PHA, which appears to be a transcription-dependent event, leads to the production and release of lymphokines supporting proliferation and differentiation of human pluripotent stem ...
L. Kanz, G. W. Löhr, H. Löhr, A. A. Fauser   +3 more
openaire   +3 more sources

Immunoregulatory T lymphocytes in man. Soluble antigen-specific suppressor-inducer T lymphocytes are derived from the CD4+CD45R-p80+ subpopulation.

Journal of Immunology, 1987
Regulation of the immune response in man is largely dependent on interactions between cells of the cluster designation 4+ (CD4+) helper/inducer sublineage and the CD8+ suppressor/cytotoxic sublineage.
N. Damle, A. Childs, L. Doyle
semanticscholar   +1 more source