Results 111 to 120 of about 14,943,986 (252)

Septin 9 PB domains coordinate centrosome positioning and microtubule acetylation to control epithelial polarity

open access: yesFEBS Letters, EarlyView.
Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai   +4 more
wiley   +1 more source

Design Pattern Detection by Using Meta Patterns [PDF]

open access: yes, 2008
One of the approaches to improve program understanding is to extract what kinds of design pattern are used in existing object-oriented software. This paper proposes a technique for efficiently and accurately detecting occurrences of design patterns ...
KOBAYASHI, Takashi   +4 more
core  

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

open access: yesFEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto   +3 more
wiley   +1 more source

Domain-sensitive weather phraseology from a constructionist perspective

open access: yesDutch Journal of Applied Linguistics
This paper looks at weather phraseology in Dutch dialects in Flanders from a CxG perspective. In this regard, our paper is situated at the interface between CxG research into phraseology, on the one hand, and CxG research into specialised discourse, on ...
Vince Liégeois, Laurent Gautier
doaj   +1 more source

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

open access: yesFEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace   +6 more
wiley   +1 more source

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

open access: yesFEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

Feed radiation patterns modified by a dichroic plate

open access: yes, 1978
The 20 GHz copolar radiation patterns of a feed 4.25 cm from a flat dichroic plate 15 cm in diameter have been computed using a mode-matching technique.
Parker, Edward A., Langsford, P.A.
core   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

open access: yesFEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa   +2 more
wiley   +1 more source

Statin prescription patterns, adherence, and attainment of cholesterol treatment goals in routine clinical care: a Danish population-based study

open access: yesClinical Epidemiology, 2015
Elisabeth Svensson,1 Rikke Beck Nielsen,1 Pål Hasvold,2 Pernilla Aarskog,2 Reimar W Thomsen1 1Department of Clinical Epidemiology, Institute of Clinical Medicine, Aarhus University Hospital, Aarhus, Denmark; 2AstraZeneca Nordic Baltic, Södert ...
Svensson E   +4 more
doaj  

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