Results 61 to 70 of about 1,857,843 (269)

Filarial Lymphedema Patients Are Characterized by Exhausted CD4+ T Cells

Frontiers in Cellular and Infection Microbiology, 2022
Worldwide, more than 200 million people are infected with filariae which can cause severe symptoms leading to reduced quality of life and contribute to disability-adjusted life years (DALYs).
Sacha Horn, Manuel Ritter, Kathrin Arndts, Dennis Borrero-Wolff, Anna Wiszniewsky, Linda Batsa Debrah, Linda Batsa Debrah, Linda Batsa Debrah, Alexander Y. Debrah, Alexander Y. Debrah, Alexander Y. Debrah, Jubin Osei-Mensah, Jubin Osei-Mensah, Mkunde Chachage, Mkunde Chachage, Mkunde Chachage, Achim Hoerauf, Achim Hoerauf, Achim Hoerauf, Inge Kroidl, Inge Kroidl, Laura E. Layland, Laura E. Layland   +22 more
doaj   +1 more source

The MedSupport Multilevel Intervention to Enhance Support for Pediatric Medication Adherence: Development and Feasibility Testing

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Introduction We developed MedSupport, a multilevel medication adherence intervention designed to address root barriers to medication adherence. This study sought to explore the feasibility and acceptability of the MedSupport intervention strategies to support a future full‐scale randomized controlled trial.
Elizabeth G. Bouchard, Hital Patel, Paula C. Vincent, Justine Kahn, Kira Bona, Thai Hoa Tran, Elisa M. Rodriguez, Kristopher Attwood, Kara M. Kelly   +8 more
wiley   +1 more source

A time-resolved meta-analysis of consensus gene expression profiles during human T-cell activation

Genome Biology, 2023
Background The coordinated transcriptional regulation of activated T-cells is based on a complex dynamic behavior of signaling networks. Given an external stimulus, T-cell gene expression is characterized by impulse and sustained patterns over the course.
Michael Rade, Sebastian Böhlen, Vanessa Neuhaus, Dennis Löffler, Conny Blumert, Maximilian Merz, Ulrike Köhl, Susann Dehmel, Katherina Sewald, Kristin Reiche   +9 more
doaj   +1 more source

Stereotactic Body Radiation Therapy for Pediatric, Adolescent, and Young Adult Patients With Osteosarcoma: Local Control Outcomes With Dosimetric Analysis

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background/Objectives Osteosarcoma is a radioresistant tumor that may benefit from stereotactic body radiation therapy (SBRT) for locoregional control in metastatic/recurrent disease. We report institutional practice patterns, outcomes, toxicity, and failures in osteosarcoma patients treated with SBRT.
Jenna Kocsis, Shauna R. Campbell, Jonathan Jang, Eashwar Somasundaram, Chandana A. Reddy, Jacob G. Scott, Lilyana Angelov, Peter M. Anderson, Matteo Trucco, Zachary Burke, Lukas Nystrom, Nathan Mesko, Anthony Magnelli, Erin S. Murphy   +13 more
wiley   +1 more source

Trypanosoma cruzi infection in neotropical wild carnivores (Mammalia: Carnivora): at the top of the T. cruzi transmission chain. [PDF]

PLoS ONE, 2013
Little is known on the role played by Neotropical wild carnivores in the Trypanosoma cruzi transmission cycles. We investigated T. cruzi infection in wild carnivores from three sites in Brazil through parasitological and serological tests.
Fabiana Lopes Rocha, André Luiz Rodrigues Roque, Juliane Saab de Lima, Carolina Carvalho Cheida, Frederico Gemesio Lemos, Fernanda Cavalcanti de Azevedo, Ricardo Corassa Arrais, Daniele Bilac, Heitor Miraglia Herrera, Guilherme Mourão, Ana Maria Jansen   +10 more
doaj   +1 more source

Patrones temporales iniciados con bloqueo directo o uno contra uno en baloncesto [PDF]

, 2017
El objetivo de la investigación fue detectar patrones temporales en secuencias ofensivas generadas a partir del bloqueo directo o el 1X1 en una competición de baloncesto de alto nivel nacional.
Hileno González, Raúl, Muñoz Arroyave, Verónica, Serna Bardavío, Jorge, Solsona Leri, Edgard, Sáez de Ocáriz Granja, Unai   +4 more
core   +1 more source

Lifestyle Behaviors and Cardiotoxic Treatment Risks in Adult Childhood Cancer Survivors

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Higher doses of anthracyclines and heart‐relevant radiotherapy increase cardiovascular disease (CVD) risk. This study assessed CVD and CVD risk factors among adult childhood cancer survivors (CCSs) across cardiotoxic treatment risk groups and examined associations between lifestyle behaviors and treatment risks.
Ruijie Li, Raquel Revuelta Iniesta, Alan R. Barker, Dimitris Vlachopoulos, Tomáš Sláma, Christina Schindera, Fabiën N. Belle   +6 more
wiley   +1 more source

Cerebrospinal Fluid Liquid Biopsy Enables Targeted Therapy Without Tissue Diagnosis in Pediatric Low‐Grade Gliomas With BRAF V600E Mutation

Pediatric Blood &Cancer, EarlyView.
ABSTRACT We present two pediatric cases of pediatric low‐grade gliomas (PLGG) with BRAF V600E mutations diagnosed and monitored using cerebrospinal fluid (CSF) liquid biopsy analyzed via digital droplet PCR (ddPCR), without tissue biopsy. Both patients were treated with dabrafenib and trametinib and monitored through clinical assessments, magnetic ...
Hannah Sultan, Damien Faury, Alexander G. Weil, Harrison J. Westwick, Nada Jabado, Sébastien Perreault   +5 more
wiley   +1 more source

The error analysis of Koshi guruma judo throw using T-Patterns [PDF]

, 2014
El objetivo de esta investigación es determinar los errores técnicos más frecuentes y sus secuencias conductuales en la proyección de judo Koshi-guruma. Los participantes (n=45; 18 hombres y 27 mujeres; M=24.22 años; DT=2.43), estudiantes universitarios ...
Ayán, C., Cancela, J., Gutiérrez-Santiago, A., Prieto, I.   +3 more
core   +1 more source

Changes in Body Composition in Children and Young People Undergoing Treatment for Acute Lymphoblastic Leukemia: A Systematic Review and Meta‐Analysis

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Ongoing evidence indicates increased risk of sarcopenic obesity among children and young people (CYP) with acute lymphoblastic leukemia (ALL), often beginning early in treatment, persisting into survivorship. This review evaluates current literature on body composition in CYP with ALL during and after treatment.
Lina A. Zahed, Raquel Revuelta Iniesta, Mary Fewtrell, Julie Lanigan, Breeana Gardiner, Graeme O'Connor   +5 more
wiley   +1 more source