Results 41 to 50 of about 1,692,892 (304)

Clinical Insights Into Hypercalcemia of Malignancy in Childhood

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Hypercalcemia of malignancy (HCM) is a rare but life‐threatening metabolic emergency in children that occurs in less than 1% of pediatric cancer cases, with a reported incidence ranging from 0.4% to 1.0% across different studies. While it is observed in 10%–20% of adult malignancies, pediatric HCM remains relatively uncommon.
Hüseyin Anıl Korkmaz
wiley   +1 more source

In-plane mixed-mode brittle fracture assessment of Harsin marble using HCSP specimen

Fracture and Structural Integrity
The primary objective of this manuscript is studying the effect of T-stress term (T) on the crack propagation angle (CPA) and fracture toughness of in-plane mixed mode loading by utilizing a generalized form of minimum strain energy density (SED ...
Z. Moqadaszadeh, H. Salavati, M. Rashidi Moghaddam   +2 more
doaj   +1 more source

Personalized Selumetinib Dosing in Pediatric Neurofibromatosis Type 1: Insights From a Pilot Therapeutic Drug Monitoring Study

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Objective To evaluate selumetinib exposure using therapeutic drug monitoring (TDM) in pediatric patients with neurofibromatosis type 1 (NF1) and plexiform neurofibromas (PN), assess interpatient pharmacokinetic variability, and explore the relationship between drug exposure, clinical response, and adverse effects.
Janka Kovács, Zoltán Köllő, Balázs Gellért Karvaly, Mahmoud Obeidat, Rita Nagy, Péter Hegyi, Brigitta Teutsch, Eszter Tuboly, Miklós Garami   +8 more
wiley   +1 more source

Adherence to Protocol Recommendations for Children With Wilms Tumour in Two Consecutive Studies in the United Kingdom and Ireland—Does Variation Matter?

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background and Aims Wilms tumour (WT) has excellent event‐free and overall survival (OS). However, small differences exist between countries participating in the same international study. This led us to examine variation in adherence to protocol recommendations as a potential contributing factor.
Suzanne Tugnait, R. Al‐Saadi, A. Lopez‐Cortes, K. Dzhuma, M. Oostveen, J. Brok, S. Irtan, M. Weeks, J. Bate, S. Baker, R. Williams, M. Powis, D. Saunders, O. Olsen, T. Watson, S. Shelmerdine, S. Vaidya, L. Howell, C. Duncan, G. M. Vujanic, C. Stiller, G. P. Balchin, T. Chowdhury, K. Pritchard‐Jones   +23 more
wiley   +1 more source

Evaluating the Utility of Paired Tumor and Germline Targeted DNA Sequencing for Pediatric Oncology Patients: A Single Institution Report

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Objective To evaluate the diagnostic yield and utility of universal paired tumor–normal multigene panel sequencing in newly diagnosed pediatric solid and central nervous system (CNS) tumor patients and to compare the detection of germline pathogenic/likely pathogenic variants (PV/LPVs) against established clinical referral criteria for cancer ...
Natalie Waligorski, Rebecca Ronsley, Shannon M. Stasi, Jeffrey Stevens, Erin R. Rudzinski, Christina M. Lockwood, Sarah E. S. Leary, Bonnie L. Cole, Michelle A. Ting, Vera Paulson   +9 more
wiley   +1 more source

Development and validation of a high constraint modified boundary layer finite element model [PDF]

, 2011
When a notched structure is loaded, its behaviour is not only affected by the material properties but also by the geometry (of both the structure and the defect) and loading condition, alternatively termed as constraint condition. Therefore, the relation
De Waele, Wim, Hertelé, Stijn, Verstraete, Matthias   +2 more
core  

Geometry functions for edge cracks in steel bridge under three- and four- point bending with various span [PDF]

, 2018
Fatigue cracks are found during the regular structural inspections. To precisely describe/suggest propagation of fatigue cracks throughout structure and it’s designed service life, the knowledge of geometry functions describing the stress situation ...
Kala, Zdeněk, Miarka, Petr, Seitl, Stanislav   +2 more
core   +1 more source

Preferences of Pediatric Patients and Their Caregivers for Chemotherapy‐Induced Nausea and Vomiting Control Endpoints: A Mixed Methods Study

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Purpose Although not always achieved, complete chemotherapy‐induced nausea and vomiting (CINV) control is the conventional goal of CINV prophylaxis. In this two‐center, mixed‐methods study, we sought to understand the preferences of adolescent patients and family caregivers for CINV control endpoints.
Haley Newman, Tadi Hondonga, Alison Berry, Caitlin Elgarten, Jason Freedman, Katelyn Oranges, Sara McDonough, Caroline Diorio, L. Lee Dupuis   +8 more
wiley   +1 more source

Exploring the Impact of Salicylic Acid and Farmyard Manure on Soil Rhizospheric Properties and Cadmium Stress Alleviation in Maize (Zea mays L.)

Plants, 2023
Cadmium (Cd) pollution is a growing environmental problem that negatively impacts plant growth and development, particularly in maize. In this research, the impact of farmyard manure (FYM) and salicylic acid (SA) on rhizospheric characteristics and the ...
Hafiz Haider Ali, Nimra Shehzadi, Muhammad Saqlain Zaheer, Mahmoud F. Seleiman, Khalid J. Aldhuwaib, Waqas ud Din Khan, Ali Raza   +6 more
doaj   +1 more source

T-stress of Concrete under Four-point Bending

Proceedings of the 9th International Conference on Fracture Mechanics of Concrete and Concrete Structures, 2016
Mixed mode stress-intensity factors (SIFs) and the T-stress for different geometries of four-point bending specimens were calculated by means of finite element analysis through a software suite Abaqus, where the influence of the loading point and crack location were considered.
Zhao Yanhua, Liu Jin
openaire   +1 more source