Results 101 to 110 of about 20,681,672 (284)

The Bayesian One-Sample t-Test Supersedes Correlation Analysis as a Test of Validity

European Journal of Psychology Open
: Introduction: The validity of measurement, which refers to how accurately tools measure what they are intended to measure, is essential in science. Researchers rely on statistical approaches to test the validity of their measures.
Phivos Phylactou, Marietta Papadatou-Pastou, Nikos Konstantinou   +2 more
doaj   +1 more source

Identification of upstream transcription factor binding sites in orthologous genes using mixed Student's t-test statistics. [PDF]

PLoS Comput Biol, 2022
Huang T, Xiao H, Tian Q, He Z, Yuan C, Lin Z, Gao X, Yao M.   +7 more
europepmc   +1 more source

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

FEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes, Jan Brysch, Carmen Gelze, Lilli Meier, Daniel Kümmel   +4 more
wiley   +1 more source

Employee assistance programmes: A study on stress reduction in trainee accountants

SA Journal of Human Resource Management
Orientation: Workplace stress has reached endemic proportions, affecting mental, physical and organisational health. Research indicates that trainee accountants experience higher levels of stress compared to other accounting professionals.
Salisha Naidu, Benjamin H. Olivier
doaj   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

FEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy, Trina Dykstra‐MacPherson, Mathias A. Bell, Peter L. Davies, Ruby May A. Sullan   +4 more
wiley   +1 more source

An Optimised Computational Framework for Cross-Cohort Metagenomic Classification Using P-Value Statistical Filtering

Applied Computer Systems
Metagenomic data analysis faces significant challenges due to high dimensionality, sparsity, and geographical heterogeneity, which limit the generalizability of diagnostic models.
Nguyen Hien Thanh Thi, Nguyen Hai Thanh
doaj   +1 more source

Beyond t test and ANOVA: applications of mixed-effects models for more rigorous statistical analysis in neuroscience research. [PDF]

Neuron, 2022
Yu Z, Guindani M, Grieco SF, Chen L, Holmes TC, Xu X.   +5 more
europepmc   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source

Development and clinical application of extendable prostheses in limb salvage surgery for primary malignant bone tumours in children: a systematic review of functional outcomes and complications

Bone & Joint Research
Aims: Extendable prostheses have developed rapidly over the decades to solve limb length discrepancy (LLD) following limb salvage surgery in children and adolescents who have suffered primary malignant bone tumours.
Ningkai Tang, Jiake Yang, Siyi Huang, Xiaodong Tang, Tao Ji   +4 more
doaj   +1 more source

Rank normalization empowers a t-test for microbiome differential abundance analysis while controlling for false discoveries. [PDF]

Brief Bioinform, 2021
Davis ML, Huang Y, Wang K.
europepmc   +1 more source