Results 111 to 120 of about 20,681,672 (284)
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Sample-size determination for the Bayesian t test and Welch's test using the approximate adjusted fractional Bayes factor. [PDF]
Behav Res Methods, 2021 Fu Q, Hoijtink H, Moerbeek M.
europepmc +1 more source
FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
Diversity and complexity in neural organoids
FEBS Letters, EarlyView.Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
Family Sculpture with Playmobil Pieces
Mit dem FSPlay werden innere "Arbeitsmodelle" (Schemata) von Bindungs-/Familien-/Partnerschafts-/Freundschaftsbeziehungen erhoben. Anhand mehrerer Spielfiguren sollen eine oder mehrere Skulpturen gestaltet werden, z. B.
Sydow, K. v.
core +1 more source
Attach importance of the bootstrap t test against Student's t test in clinical epidemiology: a demonstrative comparison using COVID-19 as an example. [PDF]
Epidemiol Infect, 2021 Zhao S +7 more
europepmc +1 more source
Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
FEBS Letters, EarlyView.Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source
An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane
FEBS Letters, EarlyView.Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa +3 more
wiley +1 more source
ECR-G-10. Experiences in Close Relationships Scale - German 10-Item Short Form
Der ECR-G-10, die Kurzform des Bochumer Bindungsfragebogens (BoBi), erfasst mit 10 Items das Erleben und Verhalten in der partnerschaftlichen Bindung im Erwachsenenalter und wurde auf der Grundlage des zweidimensionalen Modells von Bindung, das zwischen ...
Rohmann, E., Sattel, H., Neumann, E.
core +1 more source