Results 41 to 50 of about 1,516,601 (261)

Right Ventricular Electrogram Characteristics in a T1 Mapping-Validated Normal Population: Implications for Unipolar Voltage Mapping

, 2020
Objectives: The aim of this study was to define normal ventricular electrographic characteristics in T1 mapping–validated normal patients using a contemporary contact force catheter.
Lee, Adam C., Strugnell, W, Haqqani, HM, Haqqani, Haris M., Vittinghoff, Eric, Lee, AC, Vittinghoff, E, Hamilton-Craig, C, Hamilton-Craig, Christian, Strugnell, Wendy   +9 more
core   +1 more source

Gut microbiota alterations in patients with non‐small‐cell lung cancer undergoing chemoradiotherapy

Molecular Oncology, EarlyView.
We investigated the impact of concurrent chemoradiotherapy (CRT) on the gut microbiota in patients with locally advanced non‐small‐cell lung cancer. Overall gut microbiota composition remained largely stable throughout CRT while antibiotic exposure may influence microbial diversity.
Hanne Marte Nymoen, Zhi Zhao, Henrik Horndalsveen, Maria Moksnes Bjaanæs, Bjørn Henning Grønberg, Tarje Halvorsen, Tesfaye Madebo, Marianne Aanerud, Jussi Koivunen, Kersti Oselin, Saulius Cicenas, Nina Helbekkmo, Jarkko Ahvonen, Maria Silvoniemi, Tine Norman Alver, Tonje Dalen, Åsa Kristina Öjlert, Saima Jamil Farooqi, Åslaug Helland, Vilde Drageset Haakensen   +19 more
wiley   +1 more source

Optimizing photoactivation of PA‐mCherry for optical pooled CRISPR screens

FEBS Open Bio, EarlyView.
Photoactivatable PA‐mCherry finds widespread use to optically tag individual cells. However, confocal 405 nm UV laser‐scanning (normal scan) is much less efficient than widefield UV illumination, limiting the use of PA‐mCherry on confocal instruments. We remedy this limitation by reporting that rapid and repeated confocal scanning with a low‐intensity,
Sravasti Mukherjee, Giulia Zanetti, Bram van den Broek, Kees Jalink   +3 more
wiley   +1 more source

Noninvasive Mapping of the Electrophysiological Substrate in Cardiac Amyloidosis and Its Relationship to Structural Abnormalities

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2019
Background The relationship between structural pathology and electrophysiological substrate in cardiac amyloidosis is unclear. Differences between light‐chain (AL) and transthyretin (ATTR) cardiac amyloidosis may have prognostic implications. Methods and
Michele Orini, Adam J. Graham, Ana Martinez‐Naharro, Christopher M. Andrews, Antonio de Marvao, Ben Statton, Stuart A. Cook, Declan P. O'Regan, Philip N. Hawkins, Yoram Rudy, Marianna Fontana, Pier D. Lambiase   +11 more
doaj   +1 more source

T1 Mapping - Aplicações Cardíacas [PDF]

, 2022
Introdução: A ressonância magnética cardíaca é um método não invasivo de diagnóstico e seguimento das doenças do sistema cardiovascular. Avanços mais recentes permitiram o desenvolvimento da técnica de T1 mapping, que permite identificar pequenas ...
Diogo Plasencia e Quelhas
core   +1 more source

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

FEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová, Grigorii Rakhalskii, Miroslav Almáši   +2 more
wiley   +1 more source

SPG4 and Dementia: Expanding the Clinical Spectrum

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Hereditary spastic paraplegia (HSP) is a group of disorders characterized by progressive spasticity and lower limb weakness, with mutations in SPG4/SPAST being the most common cause. Detailed studies and clinical and molecular comparisons across different populations are missing.
Emanuele Panza, Arun Meyyazhagan, Eliseo Picchi, Gustavo Ribas, Ingrid Faber, Ryosuke Miyamoto, Preethi Basavaraju, Paolo Eusebi, Haripriya Kuchi Bhotla, Mario Stasi, Fabrizio Gaudiello, Francesco Patti, Filippo Maria Santorelli, Marcondes Cavalcante França Jr, José Luiz Pedroso, Orlando Graziani Povoas Barsottini, Hélio Afonso Ghizoni Teive, Peter Henry St George‐Hyslop, Toshitaka Kawarai, Antonio Orlacchio   +19 more
wiley   +1 more source

T1 mapping-based radiomics in the identification of histological types of lung cancer: a reproducibility and feasibility study

BMC Medical Imaging
Background T1 mapping can quantify the longitudinal relaxation time of tissues. This study aimed to investigate the repeatability and reproducibility of T1 mapping radiomics features of lung cancer and the feasibility of T1 mapping-based radiomics model ...
Jianqin Jiang, Yong Xiao, Jia Liu, Lei Cui, Weiwei Shao, Shaowei Hao, Gaofeng Xu, Yigang Fu, Chunhong Hu   +8 more
doaj   +1 more source

Choroid Plexus Enlargement and USPIO‐Based Inflammatory Feature in Cerebral Small Vessel Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective The choroid plexus (CP) is a key component of the blood–cerebrospinal fluid barrier (BCSFB), but its mechanism of action in cerebral small vessel disease (CSVD) remains unclear. This study investigated CP volume (CPV) alterations and their association with conventional imaging markers in CSVD and explored the underlying role of ...
Yongqiang Qu, Xiaoning Ren, Cuihua Fan, Chun Li, Lijie Zhang, Zaiqiang Zhang, Shaowu Li, Zhongmeng Lai, Bin Cai, Ying Fu, Yi Lin, Zhibao Zhu   +11 more
wiley   +1 more source

Dynamic Quantitative T1 Mapping in Orthotopic Brain Tumor Xenografts

Translational Oncology, 2016
Human brain tumors such as glioblastomas are typically detected using conventional, nonquantitative magnetic resonance imaging (MRI) techniques, such as T2-weighted and contrast enhanced T1-weighted MRI.
Kelsey Herrmann, Bernadette O. Erokwu, Mette L. Johansen, James P. Basilion, Vikas Gulani, Mark A. Griswold, Chris A. Flask, Susann M. Brady-Kalnay   +7 more
doaj   +1 more source