Results 61 to 70 of about 1,516,601 (261)

Sex‐Stratified Association of Regional Dopamine Transporter Binding With Disease Progression in Amyotrophic Lateral Sclerosis

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To clarify the clinical relevance of dopamine transporter single‐photon emission computed tomography (DAT‐SPECT) abnormalities in amyotrophic lateral sclerosis (ALS), with a prespecified focus on sex‐stratified associations with disease progression and short‐term prognosis.
Tomoya Kawazoe   +7 more
wiley   +1 more source

Comparison of T2* and Native T1 and T2 Mapping in Patients with Hemolytic Anemia

open access: yesJournal of the Indian Academy of Echocardiography & Cardiovascular Imaging
Background: Accurate myocardial iron quantification is essential for preventing iron overload cardiomyopathy, optimizing chelation therapy, and monitoring treatment response in patients with hemolytic anemias.
Rosh Varghese Georgy   +5 more
doaj   +1 more source

Levothyroxine Replacement Alleviates Thyroid Destruction in Hypothyroid Patients With Autoimmune Thyroiditis: Evidence From a Thyroid MRI Study

open access: yesFrontiers in Endocrinology, 2019
Background: Autoimmune thyroiditis (AIT) is the most frequent cause of hypothyroidism. Our previous studies have shown that magnetic resonance T1-mapping is a new technique for quantitatively evaluating the degree of thyroid destruction in AIT patients ...
Jia Liu   +5 more
doaj   +1 more source

Serbia city graphic 1:15,000 : Kragujevac / prepared ... by Defense Mapping Agency

open access: yes, 1995
Ed. 3-DMA.Relief shown by contours and spot heights. "Map information as of 1993." "WGS 84." "Grid--1,000 meter UTM zone 34." "Printed by DMA 7-95." "This sheet falls within NK 34-02 and NL 34-11, 1501A 1:250,000 and 3183 II and 3182 I, M709, 1:50,000 ...
United States. Defense Mapping Agency
core  

Neurochemical Endpoints to Inform Early‐Stage Trials of Spinocerebellar Ataxia 2 and 3 in a Multisite Setting

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Neurochemical levels measured by brain MR spectroscopy (MRS) have been proposed as endpoints for clinical trials in early‐stage spinocerebellar ataxia (SCA) trials. We tested their trial‐readiness by quantifying neurochemicals in three affected brain regions in early‐stage cohorts of SCA2 and SCA3, examining their reproducibility in ...
James M. Joers   +19 more
wiley   +1 more source

T1 Over Squared Proton Density Ratio to Characterize Multiple Sclerosis Lesions

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Differentiating remyelinated from demyelinated lesions in MS remains challenging without histological confirmation. This study introduces the T1‐to‐PD2 ratio (TPR) imaging approach and evaluates its ability to characterize MS lesions alongside other quantitative MRI (qMRI) metrics. Methods Thirty individuals with MS (mean age: 47.5 ± 
Sarah J. Wright   +10 more
wiley   +1 more source

T1 and T2-mapping in pancreatic MRI: Current evidence and future perspectives

open access: yesEuropean Journal of Radiology Open
Conventional T1- and T2-weighted magnetic resonance imaging (MRI) of the pancreas can vary significantly due to factors such as scanner differences and pulse sequence variations.
Alessandro Beleù   +2 more
doaj   +1 more source

Cognitive and Neuroimaging Divergence Between Juvenile and Adult FUS Amyotrophic Lateral Sclerosis

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disorder characterized by progressive motor neuron degeneration. Fused in sarcoma (FUS)‐associated juvenile ALS (jALS) represents a distinct and aggressive subgroup with rapid deterioration and poor prognosis.
Alexandra V. Jürs   +7 more
wiley   +1 more source

Native T1-mapping using cardiovascular magnetic resonance detects myocardium at risk during the first week following myocardial infarction in a swine model and in patients - comparison to contrast-enhanced cine steady-state free precession

open access: yesBMC Cardiovascular Disorders
Background Myocardium at risk (MaR) can be evaluated by cardiovascular magnetic resonance (CMR) imaging using contrast-enhanced steady state free precession (CE-SSFP) in patients after ST-elevation myocardial infarction (STEMI). However, CE-SSFP utilizes
Theodor Lav   +6 more
doaj   +1 more source

Faster 3D saturation-recovery based myocardial T1 mapping using a reduced number of saturation points and denoising.

open access: yesPLoS ONE, 2020
PurposeTo accelerate the acquisition of free-breathing 3D saturation-recovery-based (SASHA) myocardial T1 mapping by acquiring fewer saturation points in combination with a post-processing 3D denoising technique to maintain high accuracy and precision ...
Giovanna Nordio   +6 more
doaj   +1 more source

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