Results 41 to 50 of about 1,668,286 (262)
Myocardial infarction (MI) is a leading cause of morbidity and mortality worldwide. Although rapid diagnosis and reperfusion in the acute setting rely primarily on clinical assessment, electrocardiography, echocardiography, and invasive coronary ...
Yu Zhang, Sung Min Ko
doaj +1 more source
Introduction A long T2 relaxation time can reflect oedema, and myocardial inflammation when combined with increased plasma troponin levels. Cardiovascular magnetic resonance (CMR) T2 mapping therefore has potential to provide a key diagnostic and ...
Constantin-Cristian Topriceanu +16 more
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Gut microbiota alterations in patients with non‐small‐cell lung cancer undergoing chemoradiotherapy
We investigated the impact of concurrent chemoradiotherapy (CRT) on the gut microbiota in patients with locally advanced non‐small‐cell lung cancer. Overall gut microbiota composition remained largely stable throughout CRT while antibiotic exposure may influence microbial diversity.
Hanne Marte Nymoen +19 more
wiley +1 more source
Background The temporal progression states of the molecular and structural substrate in atrial fibrillation (AF) are not well understood. We hypothesized that these can be detected by AF electrograms and magnetic resonance imaging parametric mapping ...
Markus Rottmann +12 more
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THE PERFORMANCE ANALYSIS OF AN INDOOR MOBILE MAPPING SYSTEM WITH RGB-D SENSOR [PDF]
Over the years, Mobile Mapping Systems (MMSs) have been widely applied to urban mapping, path management and monitoring and cyber city, etc. The key concept of mobile mapping is based on positioning technology and photogrammetry.
G. J. Tsai +5 more
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In head and neck squamous cell carcinoma (HNSCC) p53 and p63 exert opposite roles on the transcription regulation of the lncRNA NEAT1. Under basal conditions, p53 levels are low and p63 represses NEAT1 expression. Upon genotoxic stress, p53 is rapidly induced, displacing p63 from the NEAT1 promoter leading to NEAT1 transcriptional activation and ...
Sara De Domenico +5 more
wiley +1 more source
The kinase SRPK1 directly interacts with the protein TOPBP1 and regulates the pre‐mRNA splicing of WIZ thereby contributing to the activation of the ATR/CHK1 replicative checkpoint in response to replicative stress. This allows cancer cells' genomic stability and survival.
Amani Shreim +17 more
wiley +1 more source
Purpose: We assessed the feasibility of qualitative, semiquantitative, and multiparametric quantitative magnetic resonance imaging (MRI) using a three-dimensional (3D) ultrashort echo time (3D-UTE) sequence together with 2D-T2 and 3D-T1 mapping sequences
Benjamin Dallaudière +6 more
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Mutant p53R273H disrupts PDPK1 homodimerization and contributes to PDPK1 activation
How mutant p53R273H drives AKT signaling is unclear. We show that p53R273H, but not wild‐type, directly binds PDPK1 via a mutation‐dependent conformational change. This interaction disrupts inhibitory PDPK1 homodimerization and enhances AKT phosphorylation.
Mei Chee Lim +11 more
wiley +1 more source
Robust Kalman Filter Aided GEO/IGSO/GPS Raw-PPP/INS Tight Integration
Reliable and continuous navigation solutions are essential for high-accuracy location-based services. Currently, the real-time kinematic (RTK) based Global Positioning System (GPS) is widely utilized to satisfy such requirements.
Zhouzheng Gao +5 more
doaj +1 more source

