Results 191 to 200 of about 1,437,788 (262)

DeepEMC-T2 Mapping: Deep Learning-Enabled T2 Mapping Based on Echo Modulation Curve Modeling

Purpose: Echo modulation curve (EMC) modeling can provide accurate and reproducible quantification of T2 relaxation times. The standard EMC-T2 mapping framework, however, requires sufficient echoes and cumbersome pixel-wise dictionary-matching steps ...
Wang, Yao, Shepherd, Timothy M., Feng, Li, Pei, Haoyang, Liu, Fang, Sodickson, Daniel K, Ben-Eliezer, Noam   +6 more
core  

Auto‐Downregulation of the Florigen FT Production Prevents Precocious Flowering in Plants

Advanced Science, EarlyView.
This study shows that the leaf vein‐expressed FD complexes with the florigen FT to bind DNA motifs in FT promoter, which antagonizes CONSTANS‐mediated FT activation to feedback down‐regulate FT expression. This prevents an excessive induction of FT expression by inductive photoperiods, thereby precluding precocious transition to flowering in ...
Shu Tian, Xiao Luo, Bowen Cui, Yuehui He
wiley   +1 more source

Artifacts in cardiac T1 and T2 mapping techniques-Influence on reliable quantification. [PDF]

J Cardiovasc Magn Reson
Fenski M, Gröschel J, Gatehouse P, Kolbitsch C, Schulz-Menger J.   +4 more
europepmc   +1 more source

UDP‐Glucose‐6‐Dehydrogenase Mediated O‐GlcNAcylation of Tight Junction Protein 1 Suppresses Metastasis in Renal Cell Carcinoma

Advanced Science, EarlyView.
Our research unveiled a regulatory paradigm wherein TRIM25 orchestrates the ubiquitin‐mediated degradation of UGDH. UGDH modulates the protein stability of TJP1 by regulating O‐GlcNAcylation levels, effectively impeding the metastasis of ccRCC. Our insights elevate UGDH to a pivotal biomarker and tumor suppressor, marking the first demonstration that ...
Xiaolin Chen, Yuhang Bao, Tao Liu, Jianhui Qiu, Yuanyuan Ma, Zedan Zhang, Chuandong Wang, Ruiyi Deng, Zheng Song, Tianyi He, Haode Liu, Jingcheng Zhou, Yizhou Wang, Kan Gong   +13 more
wiley   +1 more source

Astrocytic LMP2 Coordinates NF‐κB and TGF‐β1/Smad3 Signaling to Drive Neuroinflammation after Cerebral Ischemia/Reperfusion

Advanced Science, EarlyView.
ABSTRACT Astrocyte reactivity critically shapes neuroinflammatory outcomes after ischemic stroke, yet the upstream regulators governing astrocyte state transitions remain incompletely defined. Here, we identify the immunoproteasome subunit low molecular weight protein 2 (LMP2) as an important modulator of astrocyte functional remodeling following ...
Yanguang Mao, Rulan Ma, Zejing Lin, Huiying Zhao, Yuexian Liu, Yonghe Su, Xu Zhang, Xingyong Chen   +7 more
wiley   +1 more source

Relationship between MRI T2 mapping parameters and patellar ligament degeneration in patients with knee osteoarthritis. [PDF]

Medicine (Baltimore)
Wang K, Men J, Mao C, Lao X, Zhang Z, Li X, Huang Z, Xu X.   +7 more
europepmc   +1 more source

A Molecular Engineering Strategy to Fine‐Tune Phototoxicity of AIE Probes for Super‐Resolution Imaging of Mitochondrial Cristae Dynamics

Advanced Science, EarlyView.
Regulation of molecular packing, phototoxicity, and ROS output of AIE photosensitizers is achieved through carboxylation and alkyl‐chain‐length tuning. The probe designed via this strategy enables super‐resolution visualization of inner‐mitochondrial‐membrane cristae dynamics under controlled oxidative stress, and fluorescence‐lifetime imaging of ...
Kongqi Chen, Mengjie Wang, Chuen Kam, Zhiming Wang, Qinrong Zhang, Sijie Chen   +5 more
wiley   +1 more source

Longitudinal quantitative T2 mapping and SPECT-CT assessment of unloading therapy within a randomized controlled trial for medial knee osteoarthritis. [PDF]

Quant Imaging Med Surg
Verschueren J, Poot DHJ, van Outeren MV, Segbers M, van Es EM, Bierma-Zeinstra SMA, Reijman M, Oei EHG.   +7 more
europepmc   +1 more source

Magnetoelectric Nanoparticle‐Based Wireless Brain–Computer Interface: Underlying Physics and Projected Technology Pathway

Advanced Science, EarlyView.
Magnetoelectric nanoparticles (MENPs) enable fully wireless, minutely invasive neuromodulation, and potentially neural recording, by converting magnetic into electric and, conversely, electric into magnetic fields, respectively, at high spatiotemporal resolution.
Elric Zhang, Max Shotbolt, Mostafa Abdel‐Mottaleb, Shawnus Chen, Victoria Andre, Jieyuan Tian, Jonathan Shulgach, Max Murphy, Brian Noga, Ping Liang, Darcy Griffin, Douglas Weber, Marta Pardo, Salvador Pane, Sakhrat Khizroev   +14 more
wiley   +1 more source

Correlation between lumbar disc herniation nerve root compression and clinical symptoms: a study using lumbosacral plexus magnetic resonance neurography combined with T2 mapping. [PDF]

BMC Musculoskelet Disord
Yang R, Sun Y, Shi R, Liu Y, Zhao N, Zhang X, Li X, Peng Z.   +7 more
europepmc   +1 more source