Results 71 to 80 of about 1,437,788 (262)

Age- and Sex-Related Variations of Myocardial T2: Insights from Quantitative Mapping in a Healthy Ukrainian Population

Український журнал серцево-судинної хірургії
Background. Cardiac magnetic resonance imaging (CMR) is recognized as the gold standard for non-invasive myocardial tissue characterization. Quantitative T2 mapping provides a direct measurement of myocardial transverse relaxation time (T2), which ...
Tammo Raad, Alyona V. Sydorova, Hanna Ye. Morkovkina, Yevhen Ye. Tsasiuk   +3 more
doaj   +1 more source

Quantitative MRI Uncovers Subtle Cortical Damage in Myelin Oligodendrocyte Glycoprotein Antibody‐Associated Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To determine whether myelin‐sensitive quantitative MRI reveals microstructural abnormalities in normal‐appearing cortex (NACtx) in myelin oligodendrocyte glycoprotein antibody–associated disease (MOGAD), indicating that conventional MRI underestimates remission residual cortical injury.
Valentina Camera, Agnese Tamanti, Silvia Messina, Nicola Dall'Osto, Teresa Maltempo, Stefano Ziccardi, Matteo Foschi, Maria Grazia Piscaglia, Diana Ferraro, Francesco Crescenzo, Francesca Rossi, Albulena Bajrami, Sabrina Marangoni, Damiano Marastoni, Francesca Benedetta Pizzini, Maria Isabel Leite, Roberta Magliozzi, Patrick Waters, Massimiliano Calabrese, Jacqueline Palace, Ruth Geraldes   +20 more
wiley   +1 more source

Digital twins in traumatology and orthopedics: review of joint imaging and cost-effectiveness

Клиническая практика
Digital twins are promising tool for personalized medicine in traumatology and orthopedics. Their use enables virtual modeling of joint pathology and treatment based on patient-specific biomechanical characteristics.
Aleksandr V. Pepelyaev, Aleksey P. Prizov, Alexey V. Petryaikin, Alexandr A. Muraev, Nikolay V. Zagorodniy, Andrew A. Almazov, Farit N. Kadyrov, Valerii D. Gorpinich   +7 more
doaj   +1 more source

Baseline Neuroinflammation Stratifies TSPO‐PET Response to Disease‐Modifying Therapy in Multiple Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To investigate which baseline clinical and imaging characteristics best predict TSPO‐PET‐measurable reduction in glial activation following treatment of multiple sclerosis (MS), to utilize this information for designing more efficient biomarker‐based clinical trials targeting glial activation.
Marlene T. Morch, Markus Matilainen, Giulia N. Baldrighi, Marjo Nylund, Maija Saraste, Laura Airas   +5 more
wiley   +1 more source

In vivo biochemical 7.0 Tesla magnetic resonance : preliminary results of dGEMRIC, zonal T2, and T2* mapping of articular cartilage

, 2008
INTRODUCTION: Ultra-high-field whole-body systems (7.0 T) have a high potential for future human in vivo magnetic resonance imaging (MRI). In musculoskeletal MRI, biochemical imaging of articular cartilage may benefit, in particular.
Quirbach, S., Welsch, G. H., Scheffler, K., Kraff, O., Trattnig, S., Hughes, T, Schweitzer, M., Mamisch, T. C., Scheffler, K, Trattnig, Si, Kraff , O., Zilkens, C, Welsch, G., Schweitzer, ME, Zilkens, C., Mamisch, TC, Welsch, GG, Kraff, O, Mamisch, T., Schweitzer, M. E., Szomolanyi, P, Hughes, T., Szomolanyi, P., Quirbach, S   +23 more
core   +1 more source

Disease Course After Anti‐CD20 Discontinuation in Secondary Progressive Multiple Sclerosis—A Multicenter Long‐Term Longitudinal Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To describe long‐term outcomes after anti‐CD20 discontinuation in selected patients with secondary progressive multiple sclerosis (SPMS) who remained without subsequent disease‐modifying therapy (DMT). Methods We retrospectively analyzed data from four centers in Austria and Switzerland.
Ferdinand Otto, Dariia Kliushnikova, Richard Friedrich Radlberger, Sinan Yasaroglu, Tobias Moser, Andrea Harrer, Kitty Kratzer, Wolfgang Hitzl, Christiane Gradl, Martin Schmidauer, Patrick Roth, Harald Hegen, Peter Wipfler   +12 more
wiley   +1 more source

Progressive Parkinsonism in PPP2R5D‐Related Neurodevelopmental Disorder

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT PPP2R5D‐related neurodevelopmental disorder (Houge–Janssens syndrome type 1) is a rare autosomal dominant condition characterized by macrocephaly, intellectual disability, and epilepsy. Progressive parkinsonism is an emerging adult phenotype that neurologists should be aware of since timely genetic diagnosis opens the door to disease‐modifying
Katerina Bernardi, Enrique Gonzalez Saez‐Diez, Joshua Rong, Beril Ay, Shabbir Merchant, Kathryn Yang, Darius Ebrahimi‐Fakhari   +6 more
wiley   +1 more source

[New Guinea, scale 1:63,360] [cartographic material] /

, 1955
Provisional ed. Uncontoured (planimetric) map series of Papua New Guinea, compiled from aerial photography, showing minor roads, tracks, water features, buildings and populated places. Relief shown by spot heights.; Produced by National Mapping Office to
Australia. National Mapping Office.
core  

T2 and T2* mapping in patients after matrix-associated autologous chondrocyte transplantation: initial results on clinical use with 3.0-Tesla MRI [PDF]

, 2010
To use T2 and T2* mapping in patients after matrix-associated autologous chondrocyte transplantation (MACT) of the knee, and to compare and correlate both ...
Welsch, GH, Trattnig, S, Hughes, T, Marlovits, S, Olk, A, Mamisch, TC, Quirbach, S, Blanke, M   +7 more
core   +2 more sources

Re‐Purposing Sapropterin (Kuvan) for ACTA2‐Related Multisystemic Smooth Muscle Dysfunction Syndrome: A Translational Mechanistic and First‐In‐Human Therapeutic Report

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Multisystemic smooth muscle dysfunction syndrome (MSMDS) is an ultra‐rare, ACTA2‐related disorder characterized by severe cerebrovascular disease, aortic aneurysms, and smooth muscle dysfunction. Using molecular dynamics simulations and in silico drug screening, we identified that sapropterin dihydrochloride (Kuvan) is a candidate capable of ...
Moran Hausman‐Kedem, Noa Bielopolski, Vijai Krishnan, Shane Wald‐Altman, Shelly I Shrian, Omer Bar‐Yosef, Livia Kapusta, Claire Shamber, Patricia L. Musolino, Miguel Weil   +9 more
wiley   +1 more source