Results 121 to 130 of about 137,868 (314)

Safety Assessment and Hypoglycemic Effect of Moringa oleifera Lam. Seed Lectin (WSMoL) in Alloxan‐Induced Diabetic Mice

Journal of Applied Toxicology, EarlyView.
ABSTRACT Moringa oleifera Lam. seeds contain WSMoL, a lectin previously studied for toxicity and pharmacological effects. In this study, we investigated WSMoL (10, 25, or 50 mg/kg i.p.) for acute and 14‐day repeated‐dose toxicity, as well as genotoxicity, in Swiss mice.
Alícia Natalie Silva dos Santos, Matheus Cavalcanti de Barros, Cleidiane Silva Vieira de Souza, Ryan Cristian da Silva, Luana Cassandra Breitenbach Barroso Coelho, Maria Tereza dos Santos Correia, Fernanda das Chagas Ângelo Mendes Tenório, Alisson Macário de Oliveira, Thiago Henrique Napoleão, Robson Raion de Vasconcelos Alves, Patrícia Maria Guedes Paiva   +10 more
wiley   +1 more source

Glycemic Regulation and Renal Function by Heavy Metal Exposure: A Cross‐Sectional Analysis on Cement Plant Workers

Journal of Applied Toxicology, EarlyView.
ABSTRACT Heavy metal exposure is known to have various effects on renal function and blood glucose regulation. The main objective of this study was to evaluate the effects of cement dust and some metal (cadmium, manganese, nickel, and zinc) exposure on blood glucose and renal function parameters in male cement plant workers.
Duygu Seyhan Erdoğan, Fatma Bozdag, Fatıma Betül Topcu, Osman Burak Demirbas, Sultan Pinar Cetintepe, Mustafa Necmi Ilhan   +5 more
wiley   +1 more source

Correlation analysis of coagulation factor level and chronic low-grade inflammation in patients with type 2 diabetes mellitus complicated with ischemic stroke

Open Medicine
To analyze differences in coagulation function and plasma inflammatory factors between type 2 diabetes mellitus (T2DM) patients with and without ischemic stroke (IS), and explore related mechanisms.
Weng Li, Wang Yan, Li Dejuan
doaj   +1 more source

The effect of the keto diet on lipid profile with type two diabetic patients

Разработка и регистрация лекарственных средств
Introduction. In the developed world, among the main causes of disease and death is type 2 diabetes. It is a significant public health issue with rising prevalence, with more than 380 million patients estimated to be affected by 2025.Aim. To evaluate the
Fadwa Ghassan, Ateka Mohammed, Zainab Kazim   +2 more
doaj   +1 more source

Large‐Scale Evaluation of Traditional Chinese Medicines Reveals Potential PPARγ Modulators for Type 2 Diabetes Management

Journal of Clinical Laboratory Analysis, EarlyView.
Identifying novel treatments for diabetic management is always a competitive research topic all over the world. PPAR‐γ is one of the key regulators involved in glucose and lipid metabolism and improves insulin sensitivity and glucose homeostasis. This study investigated the impacts of 639 traditional Chinese medicine (TCM) on PPAR‐γ gene promoter ...
Mingyuan Dou, Shandra Jones, Juan Montes, Jonathan Ritter, Li‐Yu Shih, Chia‐Jung Chan, Ying‐Chou Lin, Min Chen, Shih‐Yin Chen, Ning Wu   +9 more
wiley   +1 more source

Correlation Between Serum Vitamin E and HOMA-IR in Patients with T2DM

Jing Zhang,1,2 Yilin Hou,1 Zhaozi Zhang,1 Yihe Shi,1 Zhimin Wang,1 Guangyao Song1,2 1Department of Internal Medicine, Graduate School of Hebei Medical University, Shijiazhuang, Hebei, People’s Republic of China; 2Department of Endocrinology, Hebei ...
Zhang J, Zhang Z, Hou Y, Wang Z, Song G, Shi Y   +5 more
core  

Odd ratio for T2DM and T2DM-NP per 10 ng/mL increase in serum levels of CTRP3.

, 2019
Odd ratio for T2DM and T2DM-NP per 10 ng/mL increase in serum levels of CTRP3.
Nariman Moradi (3391952), Jalil Hosseini (6619691), Ali Nobakht (6619682), Fereshteh Aliakbary (6619688), Reza Fadaei (3391958), Mohammad Jafar Rezaei (6619685), Mohammad Ebrahim Khamseh (6619679), Akram Vatannejad (6078212)   +7 more
core   +1 more source

Magnitude of, and Factors Associated with Cardiovascular Disease Among Type Two Diabetes Mellitus Patients

Diabetes, Metabolic Syndrome and Obesity, 2020
Adane Tesfaye,1 Haileyesus Josef,1 Temesgen Bizuayehu Wube,2 Zeleke Girma,1 Belay Negasa,1 Temesgen Muche,1 Bewnetu Zewude3 1Department of Public Health, School of Public Health, College of Medicine and Health Science, Dilla University, Dilla, Ethiopia ...
Tesfaye A, Josef H, Wube TB, Girma Z, Negasa B, Muche T, Zewude B   +6 more
doaj  

Circulating miR-4454 as a potential biomarker for the diagnosis of T2DM and the prediction value of comorbidity and complications in T2DM

BMC Endocrine Disorders
T2DM (type 2 diabetes mellitus) is a chronic metabolic disease that seriously affects human health. Abnormal expression of microRNAs has been reported to play an important role in disease diagnosis. This study aimed to investigate the predictive value of miR-4454 for T2DM and possible risk factors for comorbidity and complications (CC) of T2DM.Baseline
Song Yang, Mei Wang, Qin Deng
openaire   +3 more sources

Intelligent design of artificial biocatalyst for biomedical diseases

Journal of Intelligent Medicine, EarlyView.
This review summarizes recent advances in the intelligent design of artificial biocatalysts for biomedical diseases. By leveraging tailored design strategies, including environment‐responsive engineering and rational/artificial intelligence‐aided optimization, these biocatalysts enable precise modulation of pathological microenvironments and targeted ...
Lijie Zhang, Nan Song, Huanhuan Qiao, Si Sun   +3 more
wiley   +1 more source