Results 121 to 130 of about 177,759 (314)
iMetaOmics, EarlyView.This schematic illustrates how probiotics‐derived postbiotics (PLBK®1–5) combat high‐fat diet‐induced obesity. Postbiotics remodel gut microbiota, boosting beneficial metabolites. These metabolites activate adipocyte thermogenesis (Ucp1/AMPK pathway), resulting in reduced body weight, improved insulin sensitivity, and alleviated hepatic steatosis in ...
Ye Tian +7 more
wiley +1 more source
Diabetes, Metabolic Syndrome and Obesity, 2023 Yasamin Abdu,1 Sarah Naja,1 Mohamed Izham Mohamed Ibrahim,2 Mariam Abdou,1 Romaisa Ahmed,3 Salma Elhag,4 Ahmed O Saleh,5 Mohamed Yassin,6 Iheb Bougmiza7,8 1Community Medicine Department, Hamad Medical Corporation, Doha, Qatar; 2College of Pharmacy, QU ...
Abdu Y +8 more
doaj
iNew Medicine, EarlyView.ABSTRACT Aspartame and acesulfame‐K are commonly used non‐nutritive artificial sweeteners, but their impacts on cardiovascular disease and metabolic dysfunction‐associated fatty liver disease (MASLD) are unclear. In this study, we evaluated the impacts of aspartame and acesulfame‐K on MASLD and atherosclerosis in male Ldlr−/− mice fed an AMLN diet ...
Jingjing Xu +3 more
wiley +1 more source
Genetics of T2DM in 2016: Biological and translational insights from T2DM genetics.
Nature reviews. Endocrinology, 2017 Type 2 diabetes mellitus (T2DM) is a major global health challenge. Development of more effective strategies for prevention and therapy depends on an improved understanding of its pathogenetic mechanisms. 2016 ends a period during which large-scale discovery of risk alleles for T2DM became routine and heralds a shift in research focus towards their ...
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iNew Medicine, EarlyView.Metabolomic & lipidomic analysis reveals metabolic overlap between CAD & T2DM, highlighting 7 key metabolites as potential biomarkers. A predictive model based on these achieves high accuracy, potentially advancing precision medicine & metabolic insights.
Zhihua Wang +9 more
wiley +1 more source
Diabetic nephropathy, autophagy and proximal tubule protein endocytic transport: A potentially harmful relationship [PDF]
, 2018 Diabetic nephropathy (DN) is the most frequent cause of chronic renal failure. Until now, the pathophysiological mechanisms that determine its development and progression have not yet been elucidated.
Agüero, Rocio +4 more
core
Functional Context Network of T2DM
, 2011 Type-2 diabetes mellitus (T2DM) is a complex disease with multiple causes covering several functional entities of the metabolism. Environmental factors contribute to the pathogenesis of the disease – most notably nutrition and weight of the organism. The identification of disease genes is the driving power of many research projects. In a previous paper
Thormann, Anja, Rasche, Axel
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iNew Medicine, EarlyView.ABSTRACT Over the past three decades, the global burden of common metabolic diseases such as obesity, diabetes, and atherosclerosis has steadily increased, becoming a serious public health issue that poses a major threat to human health worldwide. Potassium channels, particularly the voltage‐gated Kv1.3 subtype, serve as critical regulators of cellular
Wenjun Zhen +6 more
wiley +1 more source
A Curious Case of a Murmur Unmasking a Broken Heart
Assam Journal of Internal MedicineThe development of a pseudoaneurysm as a complication of transmural myocardial infarction is an exceptionally rare occurrence. Its diagnosis primarily relies on imaging, with echocardiography serving as the most commonly used modality.
Nilanjan Majumdar +2 more
doaj +1 more source
The effect of the keto diet on lipid profile with type two diabetic patients
Разработка и регистрация лекарственных средствIntroduction. In the developed world, among the main causes of disease and death is type 2 diabetes. It is a significant public health issue with rising prevalence, with more than 380 million patients estimated to be affected by 2025.Aim. To evaluate the
Fadwa Ghassan +2 more
doaj +1 more source