Results 161 to 170 of about 137,868 (314)

QSP Modeling Shows Pathological Synergism Between Insulin Resistance and Amyloid‐Beta Exposure in Upregulating VCAM1 Expression at the BBB Endothelium

CPT: Pharmacometrics &Systems Pharmacology, Volume 14, Issue 3, Page 561-571, March 2025.
ABSTRACT Type 2 diabetes mellitus (T2DM), characterized by insulin resistance, is closely associated with Alzheimer's disease (AD). Cerebrovascular dysfunction is manifested in both T2DM and AD, and is often considered as a pathological link between the two diseases.
Zengtao Wang, Vaishnavi Veerareddy, Xiaojiao Tang, Kevin J. Thompson, Sunil Krishnan, Krishna R. Kalari, Karunya K. Kandimalla   +6 more
wiley   +1 more source

Human islet amyloid polypeptide (IAPP): a culprit of Type 2 Diabetes Mellitus (T2DM) and T2DM neuropathy

Diabetes Mellitus (DM) is one of the most prevalent global health challenges in the 21st century, impacting over 500 million individuals by 2021. Among its types, Type 2 diabetes mellitus (T2DM) accounts for more than 90% of all diabetes cases.
Albariqi, Mohammed
core  

Safety of 12‐Months Administration of Ashwagandha (Withania somnifera) Standardized Root Extract in Healthy Adults: A Prospective, Observational Study

Phytotherapy Research, EarlyView.
ABSTRACT Ashwagandha, an adaptogen, is an important herb of Ayurveda used as a Rasayana for its various health benefits. This prospective, multi‐center, observational clinical study evaluates the safety (clinical and laboratory) of a standardized Ashwagandha Root Extract (ARE) on long‐term administration over 12 months. Male and female adults (N = 191)
Jaising Salve, Sanjeev Kale, Banwari Lal Prajapati, Adele Sparavigna, Mark Savant, John Ademola, Deepak Langade   +6 more
wiley   +1 more source

Effects of GLP-1RA Treatment on Long-Term Post-PCI Prognosis in T2DM Patients: A Propensity Score Matching Study

Binbin Fang,1,* Fen Liu,1,* Junyi Luo,2 Ning Song,2 Chang Liu,2 Wei Ji,2 Xin An,2 Qian Xie,2 Yining Yang,3 Xiaomei Li2 1State Key Laboratory of Pathogenesis, Prevention and Treatment of High Incidence Diseases in Central Asia, Clinical ...
Li X, Song N, Yang Y, Luo J, Ji W, An X, Fang B, Liu C, Xie Q, Liu F   +9 more
core  

SGLT2 blockers in T2DM [PDF]

Nature Reviews Cardiology, 2018
openaire   +1 more source

Recurrence Patterns and Prognostic Factors in Sentinel Lymph Node‐Negative Melanoma in a Taiwanese Cohort With Predominant Acral Melanoma

The Journal of Dermatology, EarlyView.
ABSTRACT Cutaneous melanoma in Asian populations is characterized by a predominance of acral melanoma and distinct clinicopathologic features. Although sentinel lymph node biopsy (SLNB) is widely used for staging, a subset of SLN‐negative patients still develop recurrence, and evidence regarding recurrence patterns and prognostic factors in this group ...
Chih‐Yuan Chang, Cheng‐Yuan Li, Tien‐Hsiang Wang, Chi‐Han Tsai, Jai‐Sing Yang, Yu‐Jen Chiu   +5 more
wiley   +1 more source

Diabetes-related barriers to cancer screening in women with type 2 diabetes: A qualitative interview study. [PDF]

Br J Health Psychol
Spencer R, Jones G, McHugh S, Ajjan RA, Birch RJ, Ashley L.   +5 more
europepmc   +1 more source

Hormone Replacement Therapy for Menopausal Symptoms and the Risk of Cardiometabolic Disease: Current Evidence and Future Directions

BJOG: An International Journal of Obstetrics &Gynaecology, EarlyView.
ABSTRACT Background The transition through menopause is accompanied by a series of adverse metabolic changes which are associated with an increased risk of cardiometabolic disease, a major cause of mortality in women after midlife. Whilst the indication for menopausal hormone replacement therapy (HRT) is the control of menopausal symptoms ...
Jiawen Dong, Sarah Hillman, Sharon Dixon, Anupa Shah, Radha Venkatakrishnan, Jeremy W. Tomlinson   +5 more
wiley   +1 more source

Topological Property Impairments of Brain Functional Network in Newly-Onset Overweight/Obese Patients with Type 2 Diabetes Mellitus. [PDF]

Diabetes Metab Syndr Obes
Yu T, Zhou F, Chen J, Gao L.
europepmc   +1 more source

Bariatric Surgery, Gestational Diabetes and Perinatal Outcomes: A Population‐Based Study

BJOG: An International Journal of Obstetrics &Gynaecology, EarlyView.
ABSTRACT Objective To examine the independent and combined associations of metabolic and bariatric surgery (MBS) and gestational diabetes mellitus (GDM) with adverse maternal and neonatal outcomes. Design Population‐based retrospective cohort study. Setting New South Wales (NSW), Australia.
Tessa Weir, Ibinabo Ibiebele, Deborah Randall, Tanya Nippita, Siranda Torvaldsen, Felicity Gallimore, Jonathan Morris, Sarah Glastras   +7 more
wiley   +1 more source