Results 41 to 50 of about 578,127 (302)

Patient therapy outcome modeling in cancer organoids is improved by cancer‐associated fibroblasts and organoid assembly convolution

Molecular Oncology, EarlyView.
Patient‐derived organoids (PDOs) from pancreatic, colorectal, and gastric cancers were used to evaluate standard and experimental therapies. Incorporating cancer‐associated fibroblasts (CAFs) into organoid cultures improved patient therapy outcome prediction.
Marcin Grochowski, Liudmyla Dolinchuk, Michał Jerzak, Albert Gandurski, Tomasz Grochowski, Weronika Wojtyś, Maciej Zadrożny, Wojciech Kaźmierczak, Małgorzata Lenarcik, Marta Matejak‐Górska, Radosław Samsel, Tomasz Olesiński, Dawid Walerych   +12 more
wiley   +1 more source

The correlation between high sensitivity C-reactive protein and hypothyroidism - A cross-sectional study

Journal of Family Medicine and Primary Care
Background: In India, the prevalence of hypothyroidism is roughly 11%, substantially more significant than the 2%–4.6% seen in Western nations. The aim was to investigate high-sensitivity C-reactive protein as a prognostic marker in hypothyroid patients ...
Bhukya Mothilal, Bharat Umakant Patil, Pravinkumar V. Ghongade, Mohan Pethe, Samir Yelwatkar   +4 more
doaj   +1 more source

Lack of action of exogenously administered T3 on the fetal rat brain despite expression of the monocarboxylate transporter 8.

Endocrinology, 2011
Mutations of the monocarboxylate transporter 8 gene (MCT8, SLC16A2) cause the Allan-Herndon-Dudley syndrome, an X-linked syndrome of severe intellectual deficit and neurological impairment.
Carmen Grijota-Martínez, Diego Diez, G. Morreale de Escobar, J. Bernal, Beatriz Morte   +4 more
semanticscholar   +2 more sources

Astrócitos e hormônio da tireóide (T3): desenvolvimento neuronal e neuroproteção [PDF]

, 2008
Tese (doutorado) - Universidade Federal de Santa Catarina, Centro de Ciências Biológicas. Programa de Pós-graduação em Neurociências.O hormônio da tireóide (T3) exerce uma importante influência no desenvolvimento e maturação do SNC de mamíferos.
Aguiar, Cláudia Beatriz Nedel Mendes de
core  

Quantitative proteomic analysis reveals different characteristics of bladder cancer cells after exposure to bisphenol A

FEBS Open Bio, EarlyView.
Bisphenol A (BPA), a common chemical in plastics, exerts dual effects on bladder cancer cells: low doses promote growth and migration, while high doses suppress growth and migration. Multi‐omics and bioinformatics reveal BPA acts via MAPK and inflammatory pathways.
Shaomin Niu, Lanlan Li, Wenjuan Jia, Hanzhong Feng, Xiaoquan Yu, Youli Zhao, Fengzhi Yuan, Hui Ding, Junqiang Tian, Yong‐Xing He, Zhiping Wang   +10 more
wiley   +1 more source

Relationship between microstructure and stable pitting initiation in aerospace aluminium alloy 2024-T3

, 2010
Aluminium alloys are essential to a variety of industry sectors, particularly transport, where they are used in the production of cars and aeroplanes.
Adam Boag (20006904)
core   +1 more source

Identifying gene expression signatures for risk stratification of postoperative adjuvant chemotherapy in colorectal cancer

FEBS Open Bio, EarlyView.
A novel signature integrating genome‐wide analysis with clinical factors predicts recurrence in stage II colorectal cancer and enables a new risk stratification to guide postoperative adjuvant chemotherapy. Clinical risk stratification for postoperative recurrence in patients with pathological stage II (pStage II) colorectal cancer (CRC) is essential ...
Mayuko Otomo, Keisuke Okuno, Shuichi Watanabe, Sakiko Oba, Hiroyasu Kagawa, Masanori Tokunaga, Daisuke Ban, Yusuke Kinugasa   +7 more
wiley   +1 more source

Effects of IGFBP4 deficiency on human preadipocyte proliferation and differentiation through the IGF1R/AKT pathway

FEBS Open Bio, EarlyView.
IGFBP4 knockdown (KD) impairs preadipocyte proliferation and is associated with IGF1R protein downregulation and attenuated AKT phosphorylation. The mechanisms by which IGFBP4 KD influences the IGF1R/AKT signaling pathway involve newly synthesized proteins and lysosomal degradation pathways. Created in BioRender.
Yujia Guo, Sandy Richter, Christoph Bach, Wieland Kiess, Anna Kirstein, Diana Le Duc, Antje Garten   +6 more
wiley   +1 more source

Perbandingan Penggunaan Algoritma Krzyzak dengan Algoritma Rambatan Balik Piawai dalam Domain Peramalan

International Journal of Management Studies, 2004
Artikel ini bertujuan mengkaji prestasi rangkaian neural menggunakan algoritma Krzyzak  dengan algoritma rambatan balik piawai dalam domain peramalan. Kajian dilakukan terhadap data siri masa tak bermusimiaitu pengeluaran hasil kayu balak negara.
Razana Alwee, Roselina Sallehuddin, Siti Mariyam Hj. Shamsuddin   +2 more
doaj  

Associations of Lifestyle‐Related Factors and Psoriatic Arthritis Disease Activity: The Dutch South West Psoriatic Arthritis Study

Arthritis Care &Research, EarlyView.
Objective This study aims to investigate lifestyle‐related factors in patients with psoriatic arthritis (PsA) and their association with disease activity measurements. Methods This multicenter cohort included 938 patients who were newly diagnosed with PsA between 2013 and 2023.
Batoul Hojeij, Ilja Tchetverikov, Marc R. Kok, Marijn Vis, Yvonne Goekoop‐Ruiterman, Jessica Bijsterbosch, Paul Baudoin, Reinhard Bos, Jos H. van der Kaap, Petra Kok, Lindy‐Anne Korswagen, Jolanda J. Luime   +11 more
wiley   +1 more source