Results 81 to 90 of about 578,127 (302)

Targeting Post‐Irradiation Thyroid Dysfunction: Electrospun Scaffolds As A Dual‐Action Approach for Antioxidant and Immune Modulation

Advanced Healthcare Materials, EarlyView.
Radiation‐induced hypothyroidism follows head and neck radiotherapy due to oxidative stress and inflammation. Electrospun polycaprolactone scaffolds containing adenosine have potential to modulate thyroid repair. Scaffolds enhance thyrocyte proliferation, antioxidant enzymes glutathione peroxidase and catalase, reduce senescence and apoptosis markers ...
Maria Heim, Ella‐Louise Handley, Daniel Grant, Lizi M. Hegarty, Elaine Emmerson, Anthony Callanan   +5 more
wiley   +1 more source

Transmembrane signalling by the T cell antigen receptor. Perturbation of the T3-antigen receptor complex generates inositol phosphates and releases calcium ions from intracellular stores

Journal of Experimental Medicine, 1985
Antibodies against the T3-antigen receptor complex can activate the human T cell line, Jurkat, to produce interleukin 2 (2-5). This activation is initiated by a receptor-mediated increase in the concentration of free cytoplasmic calcium ions [Ca2+]i (3 ...
J. Imboden, J. Stobo
semanticscholar   +1 more source

Design and Synthesis of Peptide‐Polyester Conjugates for Cell‐Mediated Scaffold Degradation

Advanced Healthcare Materials, EarlyView.
This work describes polycaprolactone (PCL)‐based biomaterials engineered to degrade in response to cell‐secreted proteases. A fast‐degrading peptide (Fast) sequence is integrated into a PCL conjugate backbone to produce a biomaterial that is selectively degraded by multiple cell types compared to its scrambled control (ScrFast).
Korina Vida G. Sinad, Natasha K. Hunt, Srujan Singh, Kelly B. Seims, Yingjie Wu, E. Thomas Pashuck, Warren L. Grayson, Lesley W. Chow   +7 more
wiley   +1 more source

Long‐Term Hydrophilic, Anti‐Clotting, and Anti‐Fibrotic Dynamic Covalent Silicone‐Based Biomaterials

Advanced Healthcare Materials, EarlyView.
Dynamic covalent crosslinking of a Schiff‐base silicone elastomer with hydrazide‐functionalized polymers is demonstrated to improve the long‐term hydrophilicity as well as the anti‐fouling and anti‐clotting properties of PDMS implants. The hydrazone‐functionalized material prevents hydrophobic recovery, resists clotting, and significantly reduces ...
Norma A. Garza Flores, Eva Mueller, Robert Bui, James C. Fredenburgh, Ruiqi Yin, Rawaa Hussain, Rida A. Malik, Thomas Kalab, Dabeer Abdul‐Azeez, Fei Xu, Michael Brook, Jeffrey I. Weitz, Todd Hoare   +12 more
wiley   +1 more source

Probing corrosion initiation at interfacial nanostructures of AA2024-T3

, 2017
High-strength aluminium alloys such as AA2024-T3 are often developed by the introduction of plastic deformation to a precipitate containing microstructure.
AE Hughes (14500538), Ross Marceau (13091346), Mike Yongjun Tan (13084893), AM Glenn (15793538), Pavel Cizek (13088826), R Parvizi (15798446), Maria Forsyth (13084584)   +6 more
core  

An in vivo functional genetic screen reveals a role for the TRK-T3 oncogene in tumor progression

, 2004
Over the past decades, much has been learnt about the genes that contribute to oncogenic transformation of primary cells in vitro. However, much less is known about the genes that contribute to the later stages of tumor progression, in which cells of ...
Bernards, R.A., Medema, J.P., Shvarts, Avi, Edel, M.J., Shvarts, A., Medema, Jan Paul, Edel, Michael J., Bernards, René   +7 more
core   +1 more source

Plasmonic Enhancement of Fluorescence and Protein Dynamics in Living Mammalian Cells

Advanced Materials, EarlyView.
This study demonstrates plasmonic enhancement of the function of fluorescent voltage sensing proteins (genetically encoded voltage indicators, (GEVIs), QuasAr6) in live mammalian cells. Coupling to plasmonic nanoparticles does not just increase fluorescence, but influences the protein photocycle, creating a hybrid sensor with its response speed to ...
Marco Locarno, Qiangrui Dong, Marco Post, Xin Meng, Cristiano Glessi, Nynke Marije Hettema, Nidas Brandsma, Sebbe Blokhuizen, Alejandro Castañeda Garcia, Srividya Ganapathy, Thieme Schmidt, Lars van Roemburg, Bing Xu, Chun‐Ting Cho, Liedewij Laan, Miao‐Ping Chien, Daan Brinks   +16 more
wiley   +1 more source

To study effects of metformin on thyroid functions in type-2 diabetes mellitus in patients attending OPD at Government Medical College, Bidar

Journal of Family Medicine and Primary Care
Introduction: Metformin is one of the most used diabetes treating agents and has proved to be very effective, with a wide spectrum of efficacy, safety as well as being as agent that works at different spots in diabetes pathogenesis paradigm.
Prashant Patil, Sachin Gudage, Mahesh B. Tondare, Sangamesh B. Tondare, Praveen Ganganahalli   +4 more
doaj   +1 more source

T3 - Teaching to Teach with Technology -

, 2009
T3 goal is to develop and validate an innovative teaching program to promote the use of advanced learning technology by university teaching staff; secondary school teachers; trainers involved in VET. Key features of the program will include: theoretical
MIGLINO, ORAZIO
core  

Local T3 constant filter convergence spaces [PDF]

, 2020
Erciyes, Ayhan ( Aksaray, Yazar )In this paper, we characterize each of local T3(resp. T3′, ST̅3, ST3′) constant filter convergence spaces and investigate the relationships among these various forms.
Erciyes, Ayhan, Ayhan ERCİYES, Tesnim Meryem BARAN, Baran, Tesnim Meryem   +3 more
core   +1 more source