Results 111 to 120 of about 995,836 (254)

Penatalaksanaan Terapi Latihan Pada Pasien Paska Operasi Pemasangan Plate And Screw Pada Frakture Antebrachii 1/3 Proximal [PDF]

, 2015
Background: Bone fracture is a break continuitas. Antebrachii fracture is a fracture in the forearm radius and ulna. Divided into three parts, namely the proxsimal fracture, medial and distal from the corpus of the bone.
, Wahyuni, S. Fis. SKM, M.Kes, Melati, Rima   +1 more
core  

Selective Targeting of Immune Checkpoints HLA‐G and CD47 Using Novel Dual Signaling Protein DSP216 Promotes Innate Anticancer Immunity

Advanced Science, EarlyView.
The inhibitory immune checkpoints HLA‐G and CD47 are expressed on certain tumor types and inhibit immune cells in the tumor microenvironment. DSP216 binds specifically to cancer cells expressing both HLA‐G and CD47, and blocks their inhibitory signaling.
Lisa J. Jacob, Liat Tamir, Mufeed Abdeen, Ami Tamir, Alexandra Aronin, Itai Bloch, Roy Kahn, Iris Pecker, Mark Tykocinski, Gerwin Huls, Yaron Pereg, Ayelet Chajut, Edwin Bremer   +12 more
wiley   +1 more source

Cycle equivalence classes, orthogonal Weingarten calculus, and the mean field theory of memristive systems

Neuromorphic Computing and Engineering
It has been recently noted that for a class of dynamical systems with explicit conservation laws represented via projector operators, the dynamics can be understood in terms of lower dimensional equations.
F Caravelli
doaj   +1 more source

Tumor‐Derived Exosomes Deliver Membrane‐Bound Fgl2 to Activate FcγRIIB‐Mediated Immunosuppression in Myeloid‐Derived Suppressor Cells

Advanced Science, EarlyView.
This study reveals that the Fgl2‐FcγRIIB signaling axis is a key mechanism by which MDSCs mediate tumor immune evasion. Tumor‐derived exosomes systemically activate MDSCs via this pathway, positioning this axis as a promising broad‐spectrum target for cancer immunotherapy.
Fenglin Lin, Dingqin Cai, Chunli Jian, Yaxian Qi, Linpeng Zheng, Qiao Yang, Longyao Zhang, Diangang Chen, Lingchen Li, Ping Cai, Lingyou Sun, Luping Zhang, Jianguo Sun   +12 more
wiley   +1 more source

Assessment of hormonal parameters in long-term karate Practitioners [PDF]

, 2016
Introduction: Karate is a Japanese martial art which is widely practiced in the Western world as a form of self-defense, as well as a discipline to achieve physical and mental balance.However, little is known with respect to its specific psychobiological
Blanca-Mena, Maria Jose, Carranque-Chaves, Gabriel Angel, Manzaneque-Vázquez, Juan Manuel, Rodríguez-Peña, F.M., Sánchez-Montes, S., Vera-Fernandez, Francisca Maria   +5 more
core  

DNA Replication Errors Drive Genome‐Wide Small Inverted Triplication Dynamics

Advanced Science, EarlyView.
This study provides insight into the dynamic equilibrium mechanism of a novel structural variant, small inverted triplication (SIT), which is generated by misalignment of the 3’ flap generated under DNA replication stress with palindromic sequence. Alternatively, the end sequence may fold back on itself to form an inverted fragment.
Yi Lei, Yu Zhou, Haitao Sun, Hang Yuan, Xinyu Pei, Jessica D. Hess, Yao Yan, Zunsong Hu, Mian Zhou, Zhaohui Gu, Li Zheng, Xiwei Wu, Binghui Shen   +12 more
wiley   +1 more source

Network analysis of memristive device circuits: dynamics, stability and correlations

Journal of Physics: Complexity
Networks with memristive devices are a potential basis for the next generation of computing devices. They are also an important model system for basic science, from modeling nanoscale conductivity to providing insight into the information-processing of ...
F Barrows, F C Sheldon, F Caravelli
doaj   +1 more source

Genetic manipulation of bacteriophage T4 utilizing the CRISPR-Cas13b system

Frontiers in Genome Editing
CRISPR-Cas type II and type V systems are inefficient in modifying bacteriophage T4 genome, due to hypermodification of its DNA. Here, we present a genome editing technique for bacteriophage T4 using the type VI CRISPR-Cas system.
Yuvaraj Bhoobalan-Chitty, Yuvaraj Bhoobalan-Chitty, Mathieu Stouf, Marianne De Paepe   +3 more
doaj   +1 more source

GHRHR Deficiency Enhances Retinal Ganglion Cell Survival and Visual Functions in Experimental Glaucoma by Inhibiting Ferroptosis

Advanced Science, EarlyView.
Glaucoma, a major cause of blindness, involves retinal ganglion cell (RGC) degeneration. This study shows growth hormone‐releasing hormone receptor (GHRHR) deficiency preserves RGC survival and restores vision, unlike activation which only aids survival.
Yan Tong, Ming Ho Yam, Jiaxin Zhang, Lin Du, Linbin Zhou, Yolanda Wong Ying Yip, Bo Man Ho, Hemlata Bisnauthsing, Jiahui Li, Ivan Kong, Shushu Xu, Changzhen Fu, Karl K.H. So, Joaquim S.L. Vong, Ling‐Ping Cen, Ming‐Ming Yang, Khazeema Yousaf, Mai Har Sham, Sun On Chan, Poemen P. Chan, Chi Pui Pang, Clement C. Tham, Jing Na He, Jian Li, Wai Kit Chu   +24 more
wiley   +1 more source

Hypovitaminosis-D in medical students: Unrecognized or Undertreated [PDF]

Perspectives In Medical Research, 2018
Introduction: Vitamin D deficiency is a pandemic, non communicable disease in India and worldwide. Vitamin D, which is technically a hormone rather than a fat soluble secosteroid responsible for increasing intestinal absorption of Calcium, Magnesium,
Karunakar Ch1 , Ravinder Reddy K2 , Dilzith Arora K3 , Spandana T4
doaj