Results 31 to 40 of about 335,535 (207)

Somatostatin receptor 4 (SSTR4) is a tumor suppressor in cutaneous and head & neck squamous cell carcinomas

Molecular Oncology, EarlyView.
This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi, Tuan Khang Huynh, Adway Kadam, Zahra Kardan, Yue Yan, Amina Jamal Laham, Sampath Kumar Loganathan   +6 more
wiley   +1 more source

[Artículo traducido] Práctica clínica diaria en el manejo de la urticaria crónica en España: resultados del estudio UCREX

Actas Dermo-Sifiliográficas, 2022
Resumen: Antecedentes: La urticaria crónica (UC) es una enfermedad debilitante cuyo tratamiento es principalmente sintomático. El estudio UCREX tuvo como objetivo identificar el perfil de los pacientes con UC, el manejo de la enfermedad y la calidad de ...
M. Ferrer Puga, J.F. Silvestre Salvador, J. Bartra Tomas, A. Giménez-Arnau, M. Labrador-Horrillo, J. Miquel-Miquel, F.J. Ortiz de Frutos, J. Sastre Dominguez, A. Valero Santiago, P. Terradas-Montana, M. Vidal-Jorge, I. Jáuregui Presa   +11 more
doaj   +1 more source

Identifying gene expression signatures for risk stratification of postoperative adjuvant chemotherapy in colorectal cancer

FEBS Open Bio, EarlyView.
A novel signature integrating genome‐wide analysis with clinical factors predicts recurrence in stage II colorectal cancer and enables a new risk stratification to guide postoperative adjuvant chemotherapy. Clinical risk stratification for postoperative recurrence in patients with pathological stage II (pStage II) colorectal cancer (CRC) is essential ...
Mayuko Otomo, Keisuke Okuno, Shuichi Watanabe, Sakiko Oba, Hiroyasu Kagawa, Masanori Tokunaga, Daisuke Ban, Yusuke Kinugasa   +7 more
wiley   +1 more source

Étude des variations de paramètres anatomiques et endocriniens chez l'anguille européenne (Anguilla anguilla) femelle, sédentaire et d'avalaison : application à la caractérisation du stade argenté

Knowledge and Management of Aquatic Ecosystems, 1999
L'argenture est une transformation complexe qui fait passer les anguilles de la phase de croissance juvénile, sédentaire (stade jaune) à la phase de migration d'avalaison (stade argenté), étape initiale de la migration de reproduction océanique.
MARCHELIDON J., LE BELLE N., HARDY A., VIDAL B., SBAIHI M., BURZAWA-GÉRARD E., SCHMITZ M., DUFOUR S.   +7 more
doaj   +1 more source

Investigation of the Potential Roles of Thyroid Gland Hormones in the Pathogenesis of Thyroid Disorders [PDF]

Kirkuk Journal of Science
This study was designed to evaluate the roles of total Thyroxine T4, total T3, free Thyroxine FT4, free triiodothyronine FT3, and thyroid stimulating hormone TSH indicators in the pathogenesis of patients with thyroid diseases.
Enas Sobeih, Mohammed .Alwan, Arwa Hussein, Ali Abd Almuna'am   +3 more
doaj   +1 more source

Evolution‐guided yeast complementation reveals functional differences in human PSPH variants

FEBS Open Bio, EarlyView.
Ancient genomes can help guide which human genetic variants are tested experimentally. This study applies that idea to PSPH, a gene involved in serine biosynthesis, and uses high‐throughput yeast complementation to compare variant function. The findings reveal measurable differences among selected alleles and illustrate the value of evolution‐guided ...
Mauricio Campa‐Álvarez, Diana Ascencio, Miguel Vallebueno‐Estrada, Eduardo González‐Orozco, Christian Eduardo Martínez‐Guerrero, Rafael Montiel, Alexander DeLuna   +6 more
wiley   +1 more source

Assessment of the hormonal and antioxidant status of the sheep of different age groups

Аграрная наука Евро-Северо-Востока
The purpose of the research was to study some indicators of antioxidant and hormonal status in the body of ewes and young sheep of the Romanov breed, as well as to identify correlations between the studied indicators.
N. V. Bogolyubova
doaj   +1 more source

Influence of increased lipid content in diet in the form of treated rapeseed meal on the metabolism and milk yield of dairy cows in the first third of lactation

Veterinární Medicína, 2006
The purpose of this study was to evaluate the influence of high lipid concentration in the diet, served as calcium salts of fatty acids from rape, on metabolism and the milk yield of dairy cows during the first third of lactation.
A. Pechova, R. Dvorak, P. Drastich, V. Lubojacka, L. Pavlata, J. Poul   +5 more
doaj   +1 more source

Protocol for quantifying miRNA trafficking across the endosomal membrane

FEBS Open Bio, EarlyView.
An in vitro protocol measures miRNA uptake into endosomes isolated from mammalian cell extracts, which are free of subcellular contaminants. Performed at 37 °C in the presence of ATP, it ensures the import of single‐stranded miRNA into the endosomal lumen.
Syamantak Ghosh, Kamalika Mukherjee, Suvendra N. Bhattacharyya   +2 more
wiley   +1 more source

The correlation between high sensitivity C-reactive protein and hypothyroidism - A cross-sectional study

Journal of Family Medicine and Primary Care
Background: In India, the prevalence of hypothyroidism is roughly 11%, substantially more significant than the 2%–4.6% seen in Western nations. The aim was to investigate high-sensitivity C-reactive protein as a prognostic marker in hypothyroid patients ...
Bhukya Mothilal, Bharat Umakant Patil, Pravinkumar V. Ghongade, Mohan Pethe, Samir Yelwatkar   +4 more
doaj   +1 more source