Results 41 to 50 of about 455,384 (235)

The heterodimeric amino acid transporters (HAT) of the SLC7/SLC3 family: A structure−function relationships and relevance to human pathology

FEBS Letters, EarlyView.
Heterodimeric amino acid transporters consist of SLC7 and SLC3 family proteins arranged in a conserved structural organization. They regulate nutrient transport across cell membranes, supporting essential cellular functions. These transporters also contribute to xenobiotic/drug uptake and distribution.
Mariafrancesca Scalise, Tiziano Mazza, Raffaella Scanga, Lara Console, Michele Galluccio, Cesare Indiveri   +5 more
wiley   +1 more source

The correlation between high sensitivity C-reactive protein and hypothyroidism - A cross-sectional study

Journal of Family Medicine and Primary Care
Background: In India, the prevalence of hypothyroidism is roughly 11%, substantially more significant than the 2%–4.6% seen in Western nations. The aim was to investigate high-sensitivity C-reactive protein as a prognostic marker in hypothyroid patients ...
Bhukya Mothilal, Bharat Umakant Patil, Pravinkumar V. Ghongade, Mohan Pethe, Samir Yelwatkar   +4 more
doaj   +1 more source

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

Molecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner, Pierre Tennstedt, Randi C. Pose, Christian Müller, Katharina Besler, Svenja Schneegans, Malik Alawi, Marie C. Roesch, Sven Peine, Desiree Bonci, Joanna Budna‐Tukan, Evi Lianidou, Catherine Alix‐Panabières, Derya Tilki, Klaus Pantel   +14 more
wiley   +1 more source

Limbal Stem Cell Deficiency: Current Treatment Options and Emerging Therapies

Stem Cells International, 2016
Severe ocular surface disease can result in limbal stem cell deficiency (LSCD), a condition leading to decreased visual acuity, photophobia, and ocular pain.
Michel Haagdorens, Sara Ilse Van Acker, Veerle Van Gerwen, Sorcha Ní Dhubhghaill, Carina Koppen, Marie-José Tassignon, Nadia Zakaria   +6 more
doaj   +1 more source

Spatial and single‐nuclei transcriptomics reveals idiosyncratic and generic patterns in papillary and anaplastic thyroid cancers

Molecular Oncology, EarlyView.
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur, Joel Rodrigues Vitória, Manuel Saiselet, Ligia Craciun, Denis Larsimont, Anne Lefort, Frédérick Libert, Carine Maenhaut, Sabine Costagliola, Maxime Tarabichi, Mirian Romitti, Vincent Detours   +11 more
wiley   +1 more source

Somatostatin receptor 4 (SSTR4) is a tumor suppressor in cutaneous and head & neck squamous cell carcinomas

Molecular Oncology, EarlyView.
This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi, Tuan Khang Huynh, Adway Kadam, Zahra Kardan, Yue Yan, Amina Jamal Laham, Sampath Kumar Loganathan   +6 more
wiley   +1 more source

Association of stress and primary hypothyroidism

Journal of Family Medicine and Primary Care
Background: Hypothyroidism is the result of impaired production and secretion of thyroid hormones. The cardiovascular system is affected by fluctuations in thyroid hormone levels.
Monika Singh, Jagdish Narayan, Ruchika Thakur, Sandeep Bhattacharya, Satyendra K Sonkar, Wahid Ali   +5 more
doaj   +1 more source

Étude des variations de paramètres anatomiques et endocriniens chez l'anguille européenne (Anguilla anguilla) femelle, sédentaire et d'avalaison : application à la caractérisation du stade argenté

Knowledge and Management of Aquatic Ecosystems, 1999
L'argenture est une transformation complexe qui fait passer les anguilles de la phase de croissance juvénile, sédentaire (stade jaune) à la phase de migration d'avalaison (stade argenté), étape initiale de la migration de reproduction océanique.
MARCHELIDON J., LE BELLE N., HARDY A., VIDAL B., SBAIHI M., BURZAWA-GÉRARD E., SCHMITZ M., DUFOUR S.   +7 more
doaj   +1 more source

Investigation of the Potential Roles of Thyroid Gland Hormones in the Pathogenesis of Thyroid Disorders [PDF]

Kirkuk Journal of Science
This study was designed to evaluate the roles of total Thyroxine T4, total T3, free Thyroxine FT4, free triiodothyronine FT3, and thyroid stimulating hormone TSH indicators in the pathogenesis of patients with thyroid diseases.
Enas Sobeih, Mohammed .Alwan, Arwa Hussein, Ali Abd Almuna'am   +3 more
doaj   +1 more source

[Artículo traducido] Práctica clínica diaria en el manejo de la urticaria crónica en España: resultados del estudio UCREX

Actas Dermo-Sifiliográficas, 2022
Resumen: Antecedentes: La urticaria crónica (UC) es una enfermedad debilitante cuyo tratamiento es principalmente sintomático. El estudio UCREX tuvo como objetivo identificar el perfil de los pacientes con UC, el manejo de la enfermedad y la calidad de ...
M. Ferrer Puga, J.F. Silvestre Salvador, J. Bartra Tomas, A. Giménez-Arnau, M. Labrador-Horrillo, J. Miquel-Miquel, F.J. Ortiz de Frutos, J. Sastre Dominguez, A. Valero Santiago, P. Terradas-Montana, M. Vidal-Jorge, I. Jáuregui Presa   +11 more
doaj   +1 more source