Translocation through the conjugative Type 4 secretion system requires unfolding of its protein substrate [PDF]
Bacterial conjugation, a mechanism of horizontal gene transfer, is the major means by which antibiotic resistance spreads among bacteria (1, 2). Conjugative plasmids are transferred from one bacterium to another through a type IV secretion system (T4SS ...
Trokter, Martina, Waksman, Gabriel
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Structure of the enterococcal T4SS protein PrgL reveals unique dimerization interface in the VirB8 protein family [PDF]
Franziska Jäger +4 more
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Helicobacter pylori antibody and pepsinogen testing for predicting gastric microbiome abundance.
BACKGROUND:Although the high-throughput sequencing technique is useful for evaluating gastric microbiome, it is difficult to use clinically. We aimed to develop a predictive model for gastric microbiome based on serologic testing.
Saemi Choi +5 more
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Brucella abortus, the bacterial agent of the worldwide zoonosis brucellosis, primarily infects host phagocytes, where it undergoes an intracellular cycle within a dedicated membrane-bound vacuole, the Brucella-containing vacuole (BCV).
Erin P. Smith +4 more
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Comparative genomic analysis of Acinetobacter spp. plasmids originating from clinical settings and environmental habitats [PDF]
Bacteria belonging to the genus Acinetobacter have become of clinical importance over the last decade due to the development of a multi-resistant phenotype and their ability to survive under multiple environmental conditions.
Pistorio, Mariano +5 more
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Two intracellular and cell type-specific bacterial symbionts in the placozoan Trichoplax H2
Placozoa is an enigmatic phylum of simple, microscopic, marine metazoans(1,2). Although intracellular bacteria have been found in all members of this phylum, almost nothing is known about their identity, location and interactions with their host(3-6). We
Dubilier, N. +7 more
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Stenotrophomonas maltophilia expresses a type IV protein secretion system (T4SS) that promotes contact-dependent killing of other bacteria and does so partly by secreting the effector TfcB.
Brandi L. Cobe +5 more
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Electron Cryotomography of Bacterial Secretion Systems [PDF]
In biology, function arises from form. For bacterial secretion systems, which often span two membranes, avidly bind to the cell wall, and contain hundreds of individual proteins, studying form is a daunting task, made possible by electron cryotomography (
Abendroth +72 more
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Erratum: The structure of Legionella pneumophila LegK4 type four secretion system (T4SS) effector reveals a novel dimeric eukaryotic-like kinase [PDF]
Ali Flayhan +5 more
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