mBio, 2018 Strains of Helicobacter pylori that cause ulcer or gastric cancer typically express a type IV secretion system (T4SS) encoded by the cag pathogenicity island (cagPAI).
Emma C. Skoog +9 more
doaj +1 more source
The host protein calprotectin modulates the Helicobacter pylori cag type IV secretion system via zinc sequestration. [PDF]
PLoS Pathogens, 2014 Transition metals are necessary for all forms of life including microorganisms, evidenced by the fact that 30% of all proteins are predicted to interact with a metal cofactor.
Jennifer A Gaddy +11 more
doaj +1 more source
Brucella abortus Infection of Placental Trophoblasts Triggers Endoplasmic Reticulum Stress-Mediated Cell Death and Fetal Loss via Type IV Secretion System-Dependent Activation of CHOP. [PDF]
, 2019 Subversion of endoplasmic reticulum (ER) function is a feature shared by multiple intracellular bacteria and viruses, and in many cases this disruption of cellular function activates pathways of the unfolded protein response (UPR).
Atluri, Vidya L +14 more
core +1 more source
Complete Assembly of the Genome of an Acidovorax citrulli Strain Reveals a Naturally Occurring Plasmid in This Species [PDF]
, 2019 Acidovorax citrulli is the causal agent of bacterial fruit blotch (BFB), a serious threat to cucurbit crop production worldwide. Based on genetic and phenotypic properties, A.
Chen, Gong +6 more
core +1 more source
Molecular architecture, polar targeting and biogenesis of the Legionella Dot/Icm T4SS [PDF]
Nature Microbiology, 2019 Legionella pneumophila survives and replicates inside host cells by secreting ~300 effectors through the defective in organelle trafficking (Dot)/intracellular multiplication (Icm) type IVB secretion system (T4BSS). Here, we used complementary electron cryotomography and immunofluorescence microscopy to investigate the molecular architecture and ...
Debnath Ghosal +7 more
openaire +3 more sources
Legionella pneumophila strain 130b evades macrophage cell death independent of the effector SidF in the absence of flagellin [PDF]
, 2017 International audienceThe human pathogen Legionella pneumophila must evade host cell death signaling to enable replication in lung macrophages and to cause disease. After bacterial growth, however, L.
Abraham, Gilu +10 more
core +4 more sources
Type IV Secretion System Is Not Involved in Infection Process in Citrus
International Journal of Microbiology, 2014 The type IV secretion system (T4SS) is used by Gram-negative bacteria to translocate protein and DNA substrates across the cell envelope and into target cells. Xanthomonas citri subsp.
Tiago Rinaldi Jacob +6 more
doaj +1 more source
Type IV Effector Proteins Involved in the Medicago-Sinorhizobium Symbiosis
Molecular Plant-Microbe Interactions, 2017 In this study, we investigated genetic elements of the type IV secretion system (T4SS) found in Sinorhizobium spp. and the role they play in symbiosis. Sinorhizobium meliloti and S.
Matthew S. Nelson +2 more
doaj +1 more source
Functional genomics of a symbiotic community : shared traits in the olive fruit fly gut microbiota [PDF]
, 2019 The olive fruit fly Bactrocera oleae is a major pest of olives worldwide and houses a specialized gut microbiota dominated by the obligate symbiont “Candidatus Erwinia dacicola”. Ca. E. dacicola is thought to supplement dietary nitrogen to the host, with
Blow, F +6 more
core +2 more sources
Evolutionary Dynamics of Pathoadaptation Revealed by Three Independent Acquisitions of the VirB/D4 Type IV Secretion System in Bartonella. [PDF]
, 2017 The α-proteobacterial genus Bartonella comprises a group of ubiquitous mammalian pathogens that are studied as a model for the evolution of bacterial pathogenesis.
Chomel, B.B. +10 more
core +3 more sources