Results 91 to 100 of about 13,979,009 (326)

RAPTT: An Exact Two-Sample Test in High Dimensions Using Random Projections

open access: yes, 2014
In high dimensions, the classical Hotelling's $T^2$ test tends to have low power or becomes undefined due to singularity of the sample covariance matrix.
Li, Ping   +2 more
core   +2 more sources

Germline TP53 Mutations Causing Diamond–Blackfan Anemia: A French Report

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Diamond–Blackfan anemia is a rare congenital erythroblastopenia typically caused by mutations in ribosomal protein genes. Recently, gain‐of‐function mutations in TP53 have been identified as a novel cause of Diamond–Blackfan anemia. We report two French patients who both harbored a heterozygous TP53 deletion (NM_000546.5: c.1077delA; p ...
Rafael Moisan   +6 more
wiley   +1 more source

Informed Bayesian T-Tests

open access: yes, 2018
Across the empirical sciences, few statistical procedures rival the popularity of the frequentist t-test. In contrast, the Bayesian versions of the t-test have languished in obscurity. In recent years, however, the theoretical and practical advantages of
Gronau, Quentin F.   +2 more
core  

The Bayesian One-Sample t-Test Supersedes Correlation Analysis as a Test of Validity

open access: yesEuropean Journal of Psychology Open
: Introduction: The validity of measurement, which refers to how accurately tools measure what they are intended to measure, is essential in science. Researchers rely on statistical approaches to test the validity of their measures.
Phivos Phylactou   +2 more
doaj   +1 more source

Health‐Related Quality of Life and Symptom Severity Among Patients With PIK3CA‐Related Overgrowth Spectrum: A Mixed‐Methods Study to Understand Real‐World Experience With Alpelisib Treatment

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background PIK3CA‐related overgrowth spectrum (PROS) includes several rare overgrowth disorders resulting from somatic gain‐of‐function mutations in PIK3CA. Despite treatment advances, including the recent approval of alpelisib for PROS in the United States, literature detailing the patient experience with PROS is limited.
Vamsi Bollu   +8 more
wiley   +1 more source

Detecting a long odd hole [PDF]

open access: yes, 2016
For each integer $t\ge 5$, we give a polynomial-time algorithm to test whether a graph contains an induced cycle with length at least $t$ and ...
Chudnovsky, Maria   +2 more
core   +4 more sources

‘They Need to Hear You Say It’: Healthcare Professionals’ Perspectives on Barriers and Enablers to End‐of‐Life Discussions With Adolescents and Young Adults With Cancer

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT End‐of‐life conversations with adolescents and young adults (AYAs) with cancer rarely occur without the guidance of healthcare professionals. As a part of the ‘Difficult Discussions’ study, focused on palliative care and advance care planning discussions with AYAs with cancer, we investigated the factors that healthcare professionals identify ...
Justine Lee   +9 more
wiley   +1 more source

Preclinical safety testing of an affinity-optimised MAGE-A10 T cell receptor for adoptive T cell therapy [PDF]

open access: gold, 2015
Andrew B. Gerry   +13 more
openalex   +1 more source

Home - About - Disclaimer - Privacy