Results 41 to 50 of about 153 (67)

KCNJ4 variants disrupt inward‐rectifier potassium channel function and cause refractory epilepsy

open access: yesEpilepsia, Volume 67, Issue 6, Page 3199-3210, June 2026.
Abstract Objective Epilepsy is a common neurological disorder with a strong genetic basis, most frequently arising from ion channel dysfunction. Although multiple inwardly rectifying potassium (Kir) channels have been implicated in epileptogenesis, the contribution of KCNJ4, which encodes the Kir2.3 channel, has not previously been established in human
Hu Pan   +20 more
wiley   +1 more source

Extracellular Vesicles in the Biology and Liquid Biopsy Diagnostics of Pediatric High‐Grade Glioma – Emerging Findings and Opportunities

open access: yesJournal of Extracellular Biology, Volume 5, Issue 6, June 2026.
ABSTRACT Liquid biopsy has emerged as an important diagnostic paradigm impacting care across multiple cancer indications. This is also an area of great interest in pediatric solid tumours, including those affecting the central nervous system (CNS). Of special concern are pediatric high‐grade gliomas (pHGGs) due to the associated diagnostic complexities,
Samia Jahouri   +6 more
wiley   +1 more source

T‐Cell Acute Lymphoblastic Leukemia in a Young Patient With Andersen–Tawil Syndrome Successfully and Safely Treated With Intensive Chemotherapy Including Potential Precipitating Drugs: A Case Report After 3.5 Years of Follow‐up

open access: yeseJHaem, Volume 7, Issue 3, June 2026.
ABSTRACT Andersen–Tawil syndrome (ATS) is a rare, hereditary channelopathy characterized by periodic paralysis, cardiac arrhythmias, and sometimes developmental anomalies. No association with hematologic malignancies has previously been reported. We describe the case of a 27‐year‐old man with genetically confirmed Type 1 ATS who developed T‐cell acute ...
Ramy Rahmé   +6 more
wiley   +1 more source

Dermatological Manifestations of Glucagon‐Like Peptide‐1 Receptor Agonists

open access: yesJEADV Clinical Practice, Volume 5, Issue 2, Page 606-609, June 2026.
ABSTRACT Background Glucagon‐like peptide‐1 receptor agonists (GLP‑1 RAs) play a pivotal role in treating type 2 diabetes. Despite their widespread use, their dermatological manifestations remain under‐recognized, hence the interest of this systematic review. Objectives This systematic review aims to assess dermatological manifestations associated with
Nour Ghostine, Maya Halabi‐Tawil
wiley   +1 more source

SIMPLIFITAS TAFSIR JAMI’ AL-BAYAN MIN KHULASHAT SUWAR ALQURAN KARYA KH. MUHAMMAD BIN SULAIMAN

open access: yesAl-Bayan: Jurnal Studi Al-Qur'an dan Tafsir, 2018
Tradisi intelektual nusantara memiliki rantai sanad transimisi kuat dan bersambung, salah satunya dalam bidang tafsir al-Quran. Meskipun jumlahnya masih dapat dikatakan belum banyak, jika dikomparsikan dengan warisan intelektual di timur tengah dengan ...
Muhammad Dikron, Dindin Moh Saepudin
doaj   +1 more source

VIVID: A qPCR‐Based Platform for Sensitive and Quantitative In Vivo Tracking of Extracellular Vesicles

open access: yesAdvanced Functional Materials, Volume 36, Issue 39, 14 May 2026.
This study introduces VIVID (Vesicle In Vivo Identification using DNA), a qPCR‐based platform that tracks PCR‐amplifiable DNA tags loaded in the EVs for accurate and quantifiable EV biodistribution in vivo. ABSTRACT Extracellular vesicles (EVs) represent promising carriers for nucleic acid therapeutics, offering advantages over synthetic nanoparticles ...
Oscar Boyadjian   +5 more
wiley   +1 more source

Clinicopathological and Prognostic Implications of Epithelial‐to‐Mesenchymal Transition‐Related Immunohistochemical Markers in Resectable Pancreatic Cancer: A Retrospective Longitudinal Study

open access: yesCancer Reports, Volume 9, Issue 5, May 2026.
ABSTRACT Background Pancreatic ductal adenocarcinoma (PDAC) is the sixth leading cause of global cancer death. The process of epithelial‐to‐mesenchymal transition (EMT) is a key driver of early progression and metastasis in PDAC. Aim Our study aimed to explore the correlation between the expression of EMT markers and survival outcomes.
Ahmad Machmouchi   +15 more
wiley   +1 more source

Lipidome Analysis of Cancer Cells and Their Extracellular Vesicles Reveals Cancer‐Type‐Specific Lipid Signatures and Enables the Design of EV‐Mimetic Liposomes

open access: yesJournal of Extracellular Vesicles, Volume 15, Issue 5, May 2026.
ABSTRACT Lipid metabolism reprogramming is a hallmark of cancer, yet the global lipidome of cancer cells and their extracellular vesicles (EVs) remains poorly understood. Using mass spectrometry, we analyzed the lipid profiles of a panel of human cancer and non‐cancer cell lines along with their secreted EVs.
Noélie Douanne   +14 more
wiley   +1 more source

Teologi Asy’ari dalam Kitab Tafsir (Analisa Metode Ta’wil Tafṣīlī dalam Memahami Ayat Istiwā’)

open access: yesKalimah, 2017
Among the mutasyābihāt verses, there are verses which speak about Allah SWT substances, such as verses about hands, eyes, face, istawa', and so on. This article specifically tries to expose and review the ta'wīl tafṣīli method used by the mufasir in ...
Abdulloh Dardum
doaj   +1 more source

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