Results 81 to 90 of about 106,365 (113)

Determinants of cerebral aneurysm occlusion after embolization with the WEB device: a single-institution series of 215 cases with angiographic follow-up

Journal of NeuroInterventional Surgery, 2022
Background Woven EndoBridge (WEB) devices are becoming a reliable option for the treatment of wide-neck bifurcation aneurysms, but clear predictive factors are still missing to understand the one in five aneurysm remnant rate.
J. Cortese, J. Caroff, V. Chalumeau, S. Gallas, L. Ikka, J. Moret, Federico Sabuzi, S. Popescu, A. Ozanne, L. Grimaldi, C. Mihalea, L. Spelle   +11 more
semanticscholar   +1 more source

Exosomes derived from pulmonary metastatic sites enhance osteosarcoma lung metastasis by transferring the miR-194/215 cluster targeting MARCKS

Acta Pharmaceutica Sinica B
Osteosarcoma, a prevalent primary malignant bone tumor, often presents with lung metastases, severely impacting patient survival rates. Extracellular vesicles, particularly exosomes, play a pivotal role in the formation and progression of osteosarcoma ...
Lingyi Kong, Chao Han
exaly   +2 more sources

miR‐215‐5p is an anticancer gene in multiple myeloma by targeting RUNX1 and deactivating the PI3K/AKT/mTOR pathway

Journal of Cellular Biochemistry, 2020
This study examined the underlying mechanism of miR‐215‐5p in multiple myeloma (MM) at the molecular level. miR‐215‐5p was upregulated in bone marrow specimens of patients with MM and MM cell lines through real‐time polymerase chain reaction, and ...
Shengyun Lin
exaly   +2 more sources

miRNA‐192 and ‐215 activate Wnt/β‐catenin signaling pathway in gastric cancer via APC

Journal of Cellular Physiology, 2020
Although great progress has been made in surgical techniques, traditional radiotherapy, and chemotherapy, gastric cancer (GC) is still the most common malignant tumor and has a high mortality, which highlights the importance of novel diagnostic markers ...
Shiqi Deng, Xiaojing Zhang, Ying Qin, Wangchun Chen, Hu Fan, Xianling Feng, Jian Wang, Ruibin Yan, Yanqiu Zhao, Yulan Cheng, Yanjie Wei, Xinmin Fan, H. Ashktorab, D. Smoot, S. Meltzer, Song Li, Kuangwen Li, Yin Peng, Zhe Jin   +18 more
semanticscholar   +1 more source

Tumor suppressor miR-215 counteracts hypoxia-induced colon cancer stem cell activity

Cancer Letters, 2019
Cancer stem cells, also known as tumor-initiating cells (TICs), are a population of aggressive and self-renewing cells that are responsible for the initiation and progression of many cancers, including colorectal carcinoma.
Martin Nurmik, Petr V Nazarov, Serge Haan   +2 more
exaly   +2 more sources

miRNA‐215‐5p suppresses the aggressiveness of breast cancer cells by targeting Sox9

FEBS Open Bio, 2019
Several studies have shown that miR‐215‐5p acts as a tumor suppressor in certain cancers, but its role in the progression and metastasis of breast carcinoma remains incompletely understood. Herein, we prove that miR‐215‐5p is substantially down‐expressed
Xiao Liang Zhu
exaly   +2 more sources

Proposition 215: De Facto Legalization of Pot and the Shortcomings of Direct Democracy

Michigan Journal of Law Reform
In 1996, California voters passed Proposition 215, officially titled The Compassionate Use Act of 1996, and popularly known as the "medical marijuana" initiative.
Michael V Vitiello
semanticscholar   +1 more source

Inhibition of hydrogen sulfide synthesis reverses acquired resistance to 5-FU through miR-215-5p-EREG/TYMS axis in colon cancer cells

Cancer Letters, 2019
Acquired resistance to 5-fluorouracil (5-FU) is a major barrier to benefit from chemotherapy in colon cancer patients. Hydrogen sulfide (H2S), mainly produced by cystathionine-β-synthase (CBS), has been reported to promote the proliferation and migration
Shanwen Chen, Yucun Liu, Pengyuan Wang
exaly   +2 more sources

LncRNA–CDC6 promotes breast cancer progression and function as ceRNA to target CDC6 by sponging microRNA‐215

Journal of Cellular Physiology, 2018
Rapid proliferation and metastasis of breast cancers resulted in poor prognosis in clinic. Recent studies have proved that long noncoding RNAs (lncRNAs) were involved in tumor progression.
Xiaoli Kong, Yi Duan, Y. Sang, Yaming Li, Hanwen Zhang, Yiran Liang, Y. Liu, Ning Zhang, Qifeng Yang   +8 more
semanticscholar   +1 more source

Exosomes isolated from the miR-215-modified bone marrow mesenchymal stem cells protect H2O2-induced rat myoblasts via the miR-215/FABP3 pathway.

Experimental and molecular pathology (Print), 2021
This study aimed to investigate the potential effects of miR-215, with exosomes as carriers, against skeletal muscle injury. Exosomes were isolated from rat bone marrow mesenchymal stem cells (rBMSCs) or rBMSCs overexpressing miR-215.
Qiang Zhou, Hongchang Yang, Hongchi Pan, Hongyao Pan, Jing Zhou   +4 more
semanticscholar   +1 more source