Results 231 to 240 of about 7,267 (291)

Journey of a pill. [PDF]

Can Fam Physician
Kaur H, Parascandalo F, Krantzberg G, Ko E, Mathur N, Gill AS, Razack F, Sergeant M.   +7 more
europepmc   +1 more source

Transcranial Magnetic Stimulation as a Translational Biomarker in Early‐Phase Anti‐Seizure Medication Development: A Randomized, Double‐Blind, Placebo‐Controlled Study in Generalized Epilepsy

Clinical Pharmacology &Therapeutics, EarlyView.
One‐third of epilepsy patients remain treatment‐resistant, underscoring the need for novel anti‐seizure medications (ASMs) and reliable biomarkers of central target engagement. Cortical hyperexcitability is a hallmark of epilepsy, making excitability a valuable pharmacodynamic biomarker for early‐phase drug development supporting go/no‐go decision ...
Catherine M. E. de Cuba, Titia Q. Ruijs, Annika A. de Goede, Robert J. Doll, Maria Juachon, Michel J. A. M. van Putten, Geert Jan Groeneveld, Jules A. A. C. Heuberger   +7 more
wiley   +1 more source

Preparation and Application of Shen Ling Cao Composite Particles with Different Structures Based on Co-Spray Drying. [PDF]

Pharmaceuticals (Basel)
Li Z, Sun C, Sun P, Yang L, Yang Q, Zhu W, Guan Y, Liu W, Ming L.   +8 more
europepmc   +1 more source

Digital Transformation in Work Integration Social Enterprises: Leadership Strategies and the Role of Internal Stakeholders

Corporate Social Responsibility and Environmental Management, EarlyView.
ABSTRACT Digital transformation is increasingly reshaping how social enterprises organize work, engage stakeholders, and pursue social value. While prior research has examined digitalization in hybrid organizations, limited attention has been paid to how responsibility for inclusive digital transformation is enacted internally.
Riccardo Maiolini, Federica D’Alessandro, Paolo Landoni   +2 more
wiley   +1 more source

Development of Orally Disintegrating Tablets of Standardized <i>Rhodiola rosea</i> Extract. [PDF]

Pharmaceuticals (Basel)
Brante O, Bagons RT, Niedra S, Mazurs A, Mauriņa B, Bernatoniene J, Logviss K.   +6 more
europepmc   +1 more source

Identification and Characterization of the Designer Opioid N‐Pyrrolidino Fluetonitazene in Nasal Spray

Drug Testing and Analysis, EarlyView.
N‐Pyrrolidino fluetonitazene, a synthetic opioid, was identified and characterized in a nasal spray using GC‐MS, LC‐QTOF‐MS, NMR and FT‐IR. ABSTRACT Detection of drugs in non‐biological samples serves as a fundamental basis for identifying emerging trends in the field of new psychoactive substances and provides valuable information for optimizing ...
Fabian Picht, Valentin Cepus, Rona Hohlfeld, Julian Klingbeil, Marco Weber   +4 more
wiley   +1 more source

Innovative Galenic Formulation of Prussian Blue Tablets: Advancing Pharmaceutical Applications. [PDF]

Pharmaceuticals (Basel)
Martínez-Alonso B, Torrado Durán G, Torres Pabón NS, Peña Fernández MÁ.   +3 more
europepmc   +1 more source

Detection of the GH Analogue Redalsomatropin Alfa in Sports Drug Testing: Immunological Approaches and LC‐HRMS/MS

Drug Testing and Analysis, EarlyView.
After evaluating the compatibility of the GH analogue redalsomatropin alfa with approved doping control immunoassays for rhGH, it was implemented into the existing detection method for somatrogon employing affinity purification with GHR‐Fc‐conjugated magnetic beads, tryptic digestion, and LC‐HRMS/MS to allow for a specific and sensitive detection ...
Katja Walpurgis, Andreas Thomas, Jasmin Thelen, Bettina Majer, Maneera Al‐Jaber, Wadha Abushareeda, Mario Thevis   +6 more
wiley   +1 more source

Simple Quantification of Sticking Propensities of Pharmaceuticals with Mechanochemistry. [PDF]

Mol Pharm
Brocca M, Blade H, Nilsson Lill SO, Cruz-Cabeza AJ.   +3 more
europepmc   +1 more source

Spatial and Temporal Visualization of Polymorphic Transformations in Pharmaceutical Tablets. [PDF]

Angew Chem Int Ed Engl
Gasol-Cardona J, Ward MR, Gutowski O, Drnec J, Jandl C, Stam D, Maloney AGP, Markl D, Price SWT, Oswald IDH.   +9 more
europepmc   +1 more source